Associate Prof. Domenico Iuso is the Principal Investigator of a research team at the Department of Veterinary Medicine, University of Teramo, Italy. He obtained his master’s degree at the University of Teramo in 2009 and his PhD at the same university in 2012. He served as a Post-doctoral Researcher at Pasqualino Loi’s laboratory, University of Teramo, from 2013 to 2016; at Atsuo Ogura’s laboratory, RIKEN Institute (Japan), from 2016 to 2017; and at Saadi Khochbin’s laboratory, Institute for Advanced Biosciences (France), from 2017 to 2022. In 2023, he was appointed Associate Professor at the University of Teramo. Prof. Iuso has worked on several research projects focused on the epigenetic regulation during early mammalian embryonic development in sheep and mouse models. In 2017, he began exploring new aspects of epigenetics, particularly evaluating the impact of cell metabolism on nuclear remodeling, especially in liver physio-pathological conditions. This work was conducted in Dr. Saadi Khochbin’s team at the Institute for Advanced Biosciences in Grenoble, France, in collaboration with Dr. Carlo Petosa at the Institute of Structural Biology (IBS), Grenoble. Currently, his research focuses on the epigenetic and metabolic dynamics during early embryo development and cancer progression.