As mining engineering progresses into the deep excavation phase, the intensification of high pressure, high temperature, strong disturbances, and complex geological conditions becomes increasingly prominent. Researchers perform stability analysis on the excavation area to reduce potential safety hazards during the extraction process. Developing a detailed numerical calculation model that accurately reflects the true geological structure is essential for numerical simulation analysis in mining engineering. Based on the excellent 3D geological modeling capabilities of 3D Mine software, this paper introduces a new 3D geological and numerical unified modeling method (3DMine-Rhino-HyperMesh) involving multi-software coupling and details the specific steps and concepts of this modeling approach. Subsequently, using a certain open-pit mine in Panzhihua as a backdrop, a detailed geological and numerical unified model is established, reflecting the true geological structure of the mining area, and the potential failure mechanisms of the mine slope are analyzed. The results indicate that the modeling method aligns well with the actual geological conditions, enhancing the grid quality of the numerical model and offering a new modeling approach for simulating and analyzing large complex geological entities in mining operations.