Two new sesquiterpenoid derivatives, elgonenes M (1) and N (2), and a new shikimic acid metabolite, methyl 5-O-acetyl-5-epi-shikimate (3), were isolated from the mangrove sediment-derived fungus Roussoella sp. SCSIO 41427 together with fourteen known compounds (4–17). The planar structures were elucidated through nuclear magnetic resonance (NMR) and mass spectroscopic (MS) analyses. The relative configurations of 1–3 were ascertained by NOESY experiments, while their absolute configurations were determined by electronic circular dichroism (ECD) calculation. Elgonene M (1) exhibited inhibition of interleukin-1β (IL-1β) mRNA, a pro-inflammatory cytokine, at a concentration of 5 μM, with an inhibitory ratio of 31.14%. On the other hand, elgonene N (2) demonstrated inhibition at a concentration of 20 μM, with inhibitory ratios of 27.57%.

This report highlights the unique occurrence of secondary trauma to a tooth previously treated with regenerative endodontic therapy (RET) and the successful outcome following this secondary injury. A 10‐year‐old girl sustained initial trauma to her maxillary central incisors. Tooth 11 sustained a complicated crown fracture and was treated with pulpotomy, which promoted complete root closure. Tooth 21 initially presented with an uncomplicated crown fracture; however, subsequent radiographic examinations revealed external inflammatory root resorption (EIRR) and periapical periodontitis. RET was performed to halt EIRR, and follow‐up radiographs confirmed complete healing, indicated by a well‐defined border around the resorption surface and the absence of apical radiolucency. Seven months after the initial trauma, the patient experienced a second injury, resulting in the concussion of both Teeth 11 and 21. No intervention was needed, but the teeth were closely monitored clinically. At the 26‐month follow‐up, both teeth remained asymptomatic with no pathological findings. This case demonstrates that RET effectively arrests EIRR in a short timeframe and maintains tooth stability even after subsequent mild trauma.

Osseous choristoma is a rare, nonneoplastic lesion defined by the presence of organized lamellar bone within soft tissue. It most frequently affects the dorsal tongue. Gingival involvement is extremely rare, with only nine cases documented in the English‐language literature. This report describes a 20‐year‐old woman who presented with a well‐circumscribed, painless, firm, and sessile nodule on the buccal gingiva of the left posterior mandible. Panoramic radiography revealed no pathological alterations. The initial clinical impression was fibroma. Surgical excision was performed. Histopathology revealed well‐demarcated nodules of mature lamellar bone within a fibrous stroma, confirming the diagnosis of osseous choristoma. No recurrence was detected at the 6‐month follow‐up. This case constitutes the tenth reported instance of gingival osseous choristoma. A review of the nine previous cases is also provided to enhance diagnostic precision and clarify clinicopathologic features.