Matteo  Cesari

Prof. Dr. Matteo Cesari

1. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
+1
orcid

Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 September 2018 in Age and Ageing
Verified
Journal Article
Open access
PDF file
ACAlfonso J. Cruz-Jentoft
Alfonso J. Cruz-Jentoft
GBGülistan Bahat
Gülistan Bahat
JBJürgen Bauer
Jürgen Bauer
YBYves Boirie
Yves Boirie
OBOlivier Bruyère
Olivier Bruyère
JSJos Schols
Jos Schols
In 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.

1 June 2013 in Journal of the American Medical Directors Association
Verified
Journal Article
Closed access
JMJohn E. Morley
John E. Morley
BVBruno Vellas
Bruno Vellas
GKG. Abellan van Kan
G. Abellan van Kan
SAStefan D. Anker
Stefan D. Anker
JBJuergen M. Bauer
Juergen M. Bauer
JWJeremy Walston
Jeremy Walston

1 August 2013 in Journal of the American Medical Directors Association
Verified
Journal Article
Open access
JBJürgen Bauer
Jürgen Bauer
GBGianni Biolo
Gianni Biolo
TCTommy Cederholm
Tommy Cederholm
Matteo  CesariMatteo Cesari
Matteo Cesari
ACAlfonso J. Cruz-Jentoft
Alfonso J. Cruz-Jentoft
YBYves Boirie
Yves Boirie
New evidence shows that older adults need more dietary protein than do younger adults to support good health, promote recovery from illness, and maintain functionality. Older people need to make up for age-related changes in protein metabolism, such as high splanchnic extraction and declining anabolic responses to ingested protein. They also need more protein to offset inflammatory and catabolic conditions associated with chronic and acute diseases that occur commonly with aging. With the goal of developing updated, evidence-based recommendations for optimal protein intake by older people, the European Union Geriatric Medicine Society (EUGMS), in cooperation with other scientific organizations, appointed an international study group to review dietary protein needs with aging (PROT-AGE Study Group). To help older people (>65 years) maintain and regain lean body mass and function, the PROT-AGE study group recommends average daily intake at least in the range of 1.0 to 1.2 g protein per kilogram of body weight per day. Both endurance- and resistance-type exercises are recommended at individualized levels that are safe and tolerated, and higher protein intake (ie, ≥ 1.2 g/kg body weight/d) is advised for those who are exercising and otherwise active. Most older adults who have acute or chronic diseases need even more dietary protein (ie, 1.2-1.5 g/kg body weight/d). Older people with severe kidney disease (ie, estimated GFR <30 mL/min/1.73 m(2)), but who are not on dialysis, are an exception to this rule; these individuals may need to limit protein intake. Protein quality, timing of ingestion, and intake of other nutritional supplements may be relevant, but evidence is not yet sufficient to support specific recommendations. Older people are vulnerable to losses in physical function capacity, and such losses predict loss of independence, falls, and even mortality. Thus, future studies aimed at pinpointing optimal protein intake in specific populations of older people need to include measures of physical function.

1 December 2009 in The Journal of nutrition, health and aging
Verified
Journal Article
Open access
PDF file
GKGabor Abellan Van Kan
Gabor Abellan Van Kan
YRY. Rolland
Y. Rolland
SAS. Andrieu
S. Andrieu
JBJ. Bauer
J. Bauer
OBO. Beauchet
O. Beauchet
BVB. Vellas
B. Vellas
The use of a simple, safe, and easy to perform assessment tool, like gait speed, to evaluate vulnerability to adverse outcomes in community-dwelling older people is appealing, but its predictive capacity is still questioned. The present manuscript summarises the conclusions of an expert panel in the domain of physical performance measures and frailty in older people, who reviewed and discussed the existing literature in a 2-day meeting held in Toulouse, France on March 12–13, 2009. The aim of the IANA Task Force was to state if, in the light of actual scientific evidence, gait speed assessed at usual pace had the capacity to identify community-dwelling older people at risk of adverse outcomes, and if gait speed could be used as a single-item tool instead of more comprehensive but more time-consuming assessment instruments.

1 January 2009 in Ageing Research Reviews
Verified
Journal Article
Closed access
HCHae Young Chung
Hae Young Chung
Matteo  CesariMatteo Cesari
Matteo Cesari
SAStephen Anton
Stephen Anton
Emanuele MarzettiEmanuele Marzetti
Emanuele Marzetti
SGSilvia Giovannini
Silvia Giovannini
Christiaan LeeuwenburghChristiaan Leeuwenburgh
Christiaan Leeuwenburgh

22 November 2018 in The Journal of nutrition, health and aging
Verified
Journal Article
Open access
PDF file
EDElsa Dent
Elsa Dent
JMJ. E. Morley
J. E. Morley
ACAlfonso J. Cruz-Jentoft
Alfonso J. Cruz-Jentoft
HAH. Arai
H. Arai
SKS. B. Kritchevsky
S. B. Kritchevsky
BVB. Vellas
B. Vellas
Sarcopenia, defined as an age-associated loss of skeletal muscle function and muscle mass, occurs in approximately 6 - 22 % of older adults. This paper presents evidence-based clinical practice guidelines for screening, diagnosis and management of sarcopenia from the task force of the International Conference on Sarcopenia and Frailty Research (ICSFR).