The hydrodynamics of the flow around piers affects the motion of ships navigating near these structures, while the motion of the ships, in turn, affects the distribution of the flow field near the piers. This study investigates the forces exerted on a ship in various ship–pier transverse distances using commercial computational fluid dynamics (CFD) software, Fluent 13.0, based on the RNG k-ε model, complemented by experiments with a physical model. The interaction between the ship’s motion and the flow field near the piers was considered. The results indicate that during the encounter between the ship and the pier, the boundary of the approaching ship affects the flow field near the pier, thereby affecting the generation and detachment of vortices behind the pier. The yaw moment of the ship demonstrates a marked “positive peak–negative peak–positive peak” pattern. Moreover, as the ship–pier transverse distance increases, the impact of the pier on the ship’s motion decreases, and it becomes negligible when the distance reaches 0.9 times the diameter of the pier (D), suggesting that the pier has a minimal impact on ship navigation if the ship–pier transverse distance exceeds this threshold.