Isabel Betlloch-Mas

Prof. Dr. Isabel Betlloch-Mas


Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
28 November 2021 in Cureus
Verified
Journal Article
Open access
IBIsabel Betlloch-Mas
Isabel Betlloch-Mas
TSTamara Soriano-García
Tamara Soriano-García
IEIgnacio Boira Enrique
Ignacio Boira Enrique
JPJuan Carlos Palazón
Juan Carlos Palazón
GJGloria Juan-Carpena
Gloria Juan-Carpena
ECEusebi Chiner
Eusebi Chiner
Background: Cutaneous metastasis (CM), while uncommon, is usually an indicator of poor prognosis. With cancer patients living longer, the incidence of CM has increased, which justifies its analysis. Objectives: The objective of this study was to carry out a descriptive study of CM diagnosed for 18 years in a dermatology department of a tertiary care hospital and to assess the epidemiological, clinical, and histological variables that condition them, as well as data on their survival and prognosis. Methods: We performed a descriptive study of cases of CM diagnosed over 18 years in the dermatology department of a tertiary referral hospital analyzing the following variables: patient age and sex, site of primary neoplasm, pathochronology, survival time, histological findings, immunohistochemical markers, the anatomical area affected, the clinical appearance of the metastasis, therapeutic plan, and existence of metastases in other regions. We checked normal distribution using the Kolmogorov-Smirnov test and then compared the quantitative variables using the Student's t-test (unpaired samples), Mann-Whitney test (non-normal distribution), analysis of variance (ANOVA; for more than two groups), and categorical variables using the chi-square or Fisher’s exact test. Results: We included 37 cases (20 men and 17 women), of whom 32 had died. The mean age was 62 ± 15 years. CM detection was defined early in 8% of cases, synchronous in 32%, and metachronous in 60%. The most frequent primary tumor sites were lungs (24%), breasts (21%), and bladders (11%). Most metastases were solitary. The most frequent locations for CM were the scalp, trunk, armpits, and groin. Most lesions had a nodular presentation (81%). Squamous cell carcinoma and adenocarcinoma showed the same frequency in lung cancer CM. Breast cancer leading to CM was the most common invasive ductal carcinoma. The most aggressive cases, with the worst survival, originated in lung neoplasms. Therapeutic management for most patients involved surgery in combination with other procedures. The only difference detected between the lung and breast cancer CM was the predominance of lung tumors in men (89%) and breast tumors in women compared with metastases from other sites; breast cancer CM manifested more frequently as plaques and less frequently as nodules (p < 0.05) and was less frequently associated with multisystemic metastasis. In lung cancer CM, time from tumor diagnosis to CM occurrence was shorter (p < 0.01) and multisystemic metastasis was more frequent than in CM of other tumors. Conclusions: CM tends to affect patients aged above 60 years and arises predominantly from lung cancer in men and breast cancer in women. The most typical locations are the chest and scalp, and the appearance is usually nodular. Survival after CM detection is low, particularly in lung cancer CM.

1 November 2012 in Actas Dermo-Sifiliograficas
Verified
Journal Article
Closed access
IBIsabel Betlloch-Mas
Isabel Betlloch-Mas
MMM.T. Martínez-Miravete
M.T. Martínez-Miravete
ALA. Lucas-Costa
A. Lucas-Costa
ALA.I. Martin de Lara
A.I. Martin de Lara
JSJ. Selva-Otalaurruchi
J. Selva-Otalaurruchi

1 March 2019 in Actas Dermo-Sifiliograficas
Verified
Journal Article
Closed access
IBIsabel Betlloch-Mas
Isabel Betlloch-Mas
RRR. Ramón-Sapena
R. Ramón-Sapena
CAC. Abellán-García
C. Abellán-García
JPJ.C. Pascual-Ramírez
J.C. Pascual-Ramírez

18 March 2020 in Journal of Telemedicine and Telecare
Verified
Journal Article
Closed access
PDF file
IBIsabel Betlloch-Mas
Isabel Betlloch-Mas
MMMaría-Teresa Martínez-Miravete
María-Teresa Martínez-Miravete
LBLaura Berbegal-DeGracia
Laura Berbegal-DeGracia
LSLaura Sánchez-Vázquez
Laura Sánchez-Vázquez
JSJosé Sánchez-Payá
José Sánchez-Payá
Introduction: Teledermatology can solve diagnostic and therapeutic problems in paediatrics, for example in infantile haemangiomas (IHs) requiring early treatment with propranolol. This study aims to assess the impact of teledermatology following its implementation in a health area of Spain, specifically analysing its effectiveness in reducing the age of first propranolol treatment for IH. Methods: This was a descriptive study of paediatric teledermatology from 2015 to 2018, studying age, sex, diagnosis, time and mode of resolution. All IHs referred via teledermatology were analysed, and age at propranolol initiation was compared to the period prior to implementation (2008–2014). We also analysed IHs according to referral pathways (teledermatology vs. conventional pathways). Results: We included 432 consultations (47.7% boys). The main diagnoses were IH, erythematous-desquamative diseases and infections. Concordance in diagnosis between paediatricians and dermatologists was good, and 48.12% of cases consulted via teledermatology were resolved remotely. Response time was 2.81 days on average. Children younger than two months of age showed the highest proportion of in-person visits. In 2015–2018, children with IHs began treatment with propranolol at a mean age of 4.5 months (1.9 months in those referred via teledermatology vs. 5.6 months in those using conventional referral pathways). In 2008–2014, the mean age at referral was 7.1 months. These differences were significant. Discussion: Teledermatology is a fast and effective tool to resolve paediatric cases, enabling a significant decrease in the age of treatment in infants with IH.

7 April 2024 in Children
Verified
Journal Article
Open access
PDF file
IBIsabel Betlloch-Mas
Isabel Betlloch-Mas
EVElena Boluda Verdú
Elena Boluda Verdú
NJNoelia Jara-Rico
Noelia Jara-Rico
Verónica Sánchez-GarcíaVerónica Sánchez-García
Verónica Sánchez-García
LGLaura Berbegal-De Gracia
Laura Berbegal-De Gracia
ECEusebi Chiner
Eusebi Chiner
We conducted a two-year retrospective evaluation of infants aged under two years with a confirmed, clinical, or suspected diagnosis of scabies in a healthcare center in Alicante (Spain) to determine possible factors associated with diagnostic delay and poor treatment response. We collected epidemiological, clinical, diagnostic, and treatment variables. After describing our findings as mean values and percentages, we compared categorical variables using the Student’s t-test and the Mann–Whitney U test, and we compared continuous variables with the Chi2 test and Pearson’s correlation coefficient. We included 51 infants (19 boys and 32 girls) with a mean age of 15 months. The main source of contagion was the family; half of the infants lived with four or more people. According to the International Consensus Criteria for the Diagnosis of Scabies, confirmed scabies was diagnosed in 45% of cases and clinical scabies in 47%, and 45% of cases had a diagnostic delay. Lesions mainly affected the hands, feet, and trunk, with papules in 92% of cases and burrows in 55%. The predominant symptoms were pruritus (94%) and irritability (69%). Regarding treatment, 98% of the infants received topical permethrin and 35% received oral ivermectin. Treatment failed in 76% of infants. Living in large family units was associated with a higher risk of contagion and therapeutic failure. Diagnostic delay was associated with previous misdiagnosis.

1 September 2002 in International Journal of Dermatology
Verified
Journal Article
Closed access
PDF file
GVGloria Vergara
Gloria Vergara
IBIsabel Betlloch-Mas
Isabel Betlloch-Mas
MAMaría Pilar Albares
María Pilar Albares
JPJosé Carlos Pascual
José Carlos Pascual
JGJaime Guijarro
Jaime Guijarro
RBRafael Botella
Rafael Botella