Background: The analysis of health and medical data is crucial for improving the diagnosis precision, treatments and prevention. In this field, machine learning techniques play a key role. However, the amount of health data acquired from digital machines has high dimensionality and not all data acquired from digital machines are relevant for a particular disease. Primary Progressive Aphasia (PPA) is a neurodegenerative syndrome including several specific diseases, and it is a good model to implement machine learning analyses. In this work, we applied five feature selection algorithms to identify the set of relevant features from 18F-fluorodeoxyglucose positron emission tomography images of the main areas affected by PPA from patient records. On the other hand, we carried out classification and clustering algorithms before and after the feature selection process to contrast both results with those obtained in a previous work. We aimed to find the best classifier and the more relevant features from the WEKA tool to propose further a framework for automatic help on diagnosis. Dataset contains data from 150 FDG-PET imaging studies of 91 patients with a clinic prognosis of PPA, which were examined twice, and 28 controls. Our method comprises six different stages: (i) feature extraction, (ii) expertise knowledge supervision (iii) classification process, (iv) comparing classification results for feature selection, (v) clustering process after feature selection, and (vi) comparing clustering results with those obtained in a previous work. Results: Experimental tests confirmed clustering results from a previous work. Although classification results for some algorithms are not decisive for reducing features precisely, Principal Components Analisys (PCA) results exhibited similar or even better performances when compared to those obtained with all features. Conclusions: Although reducing the dimensionality does not means a general improvement, the set of features is almost halved and results are better or quite similar. Finally, it is interesting how these results expose a finer grain classification of patients according to the neuroanatomy of their disease.

Discrete Event Specification (DEVS) environments are implemented over middleware systems such as HLA, RMI, CORBA and others. DEVS exhibits concepts of systems theory and modeling and supports capturing the system behavior from the physical and behavioral perspectives. Further, they are implemented using object-oriented languages like Java and C++. This research work uses the Java platform to implement DEVS over a Service Oriented Architecture (SOA) framework. Called the DEVS/SOA, the framework supports a development and testing environment known as DEVS Unified Process that is built on a model continuity-based lifecycle methodology. DEVS Unified Process allows DEVS-based Modeling and Simulation (M&S) over net-centric platforms using DEVS/SOA. This framework also provides the crucial feature of run-time composability of coupled systems using SOA. We describe the architecture and designs of the server and the client. The client application communicates with multiple servers hosting DEVS simulation services. These simulation services are developed using the proposed symmetrical services architecture wherein the server can act as both a service provider and a service consumer contrary to the unidirectional client—server paradigm. We also discuss how this services-based architecture provides solutions for cross-platform distributed M&S. We demonstrate the DEVS/SOA framework with a scenario of Joint Close Air Support specified in Business Process Modeling Notation (BPMN). We also provide a real-world application of network health monitoring using DEVS/SOA-layered architectural framework.

The advent of edge computing holds immense promise for advancing the digitization of society, ushering in critical applications that elevate the overall quality of life. Yet, the practical implementation of the edge paradigm proves more challenging than anticipated, encountering disruptions primarily due to the constraints of applying conventional cloud‐based strategies at the network's periphery. Increasingly influenced by sustainability commitments, industry regulations currently view edge computing as a potential threat, primarily due to the energy inefficiency of solutions situated in close proximity to data generation sources and the rising density of computing. This paper presents a proactive strategy to transform the perceived threat into an opportunity, steering the sustainable evolution of future edge infrastructures to make them both environmentally and economically competitive for accelerated adoption. The vision outlined addresses key challenges associated with edge deployment and operation, emphasizing energy efficiency, fault‐tolerant automation, and collaborative orchestration. The proposed approach integrates two‐phase immersion cooling, formal modeling, machine learning, and federated management to effectively harness heterogeneity, propelling the sustainability of edge computing. To substantiate the efficacy of this approach, the paper details initial efforts towards establishing the sustainability of an edge infrastructure designed for an Advanced Driver Assistance Systems application.