Alice Elena Diaconu

Dr. Alice Elena Diaconu

orcid

Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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26 February 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
BOBogdan Oprita
Bogdan Oprita
IOIonut Olaru
Ionut Olaru
LBLiviu Botezatu
Liviu Botezatu
ADAlice Elena Diaconu
Alice Elena Diaconu
RORuxandra Bujor Oprita
Ruxandra Bujor Oprita
Severe hypothermia is a medical emergency that can be fatal if not promptly and effectively managed. Background: This case report examines a patient with severe hypothermia and describes the advanced approaches utilized in treatment, highlighting the challenges encountered and the clinical decisions that led to a favorable outcome. Methods: We report a case of an approximately 60-year-old adult, who was found unconscious in low-temperature conditions, presenting with bradycardia and a measured core temperature of 25 °C. Results: Medical intervention included active internal rewarming and the use of a controlled intravascular active heating system to support vital functions. Conclusions: This case underscores the importance of a multidisciplinary approach and the advantages of utilizing modern technologies in the management of severe hypothermia for selected cases.

3 December 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
BOBogdan Oprita
Bogdan Oprita
ADAlice Elena Diaconu
Alice Elena Diaconu
BDBogdan Dinu
Bogdan Dinu
AGAnca Arina Ghiorghiu
Anca Arina Ghiorghiu
RORuxandra Bujor Oprita
Ruxandra Bujor Oprita
Background: Caustic ingestion represents a severe clinical emergency, leading to variable and often unpredictable outcomes. The severity depends on the nature of the corrosive agent, the amount ingested, and the timing of management. Summary: This review provides an updated overview of post-caustic esophagitis, integrating epidemiology, pathophysiology, clinical spectrum, diagnostic strategies, and management principles. Special emphasis is placed on complications such as strictures, fistulas, and long-term nutritional consequences. To illustrate practical aspects, we present two recent cases managed in our department, reflecting the contrasting patterns of acid and alkali injury. A brief reference to our previously published retrospective analysis of 188 patients referred to Clinical Emergency Hospital of Bucharest between January 2003–January 2004 complements this clinical perspective. Conclusions: Post-caustic esophagitis remains a major therapeutic challenge. Early endoscopic assessment, individualized management, and multidisciplinary follow-up are crucial to improving patient outcomes. Preventive strategies and public education are equally essential to reduce the incidence of this life-threatening condition.

21 March 2026 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
BOBogdan Oprita
Bogdan Oprita
BGBurlacu Georgeta
Burlacu Georgeta
VIVlad Ispas
Vlad Ispas
CVCristina Virag-Iorga
Cristina Virag-Iorga
ADAlice Elena Diaconu
Alice Elena Diaconu
RORuxandra Bujor Oprita
Ruxandra Bujor Oprita
Background: Burn injuries have both physical and psychological impacts on patients. Factors such as personal beliefs, prior experiences, and geographic, economic, or cultural barriers, as well as fear of hospitals, can contribute to delays in seeking specialized care. When combined with inadequate first aid or the inappropriate use of pharmaceutical or traditional remedies, these delays may worsen burn severity, prolong healing, and negatively affect quality of life. From a clinical perspective, delayed presentation following burn injury has been linked to burn wound progression, which increases the risk of local infection, hypertrophic scarring and prolonged functional impairment. Methods: This analytical cross-sectional study was conducted at the Clinical Emergency Hospital of Bucharest between January and September 2025. The primary objective was to characterize adult burn patients presenting more than 24 h after injury (Group A) and to describe self-reported psychosocial/behavioral characteristics and explore unadjusted patterns among delayed presenters. Data were collected from medical records and a structured questionnaire administered to delayed presenters. A secondary descriptive comparison was performed with patients presenting within 24 h (Group B) to provide contextual reference. Results: The majority of patients were male (62.2%) and of working age (18–65 years, 82.4%). Thermal burns from domestic accidents were most common (58.8%), with scalds predominating. Second-degree burns were the most frequent (60.5%), primarily affecting the upper and lower limbs. Mean total body surface area (TBSA) was low (2.86 ± 1.91%), although higher values were observed in radiation burns and closed-space accidents. More than half of the patients did not receive any first aid, while the remainder used various pharmaceutical or natural products, some of which were inappropriate for burn treatment. The main reasons for delaying specialized care were the expectation that injuries would heal spontaneously, negligence, and fear of the hospital. In contrast, escalating pain, edema, and family insistence were the primary motivators for seeking professional medical attention. Delayed presentation was associated with older burn lesions, higher burn severity and an increased likelihood of hospitalization or refusal of recommended admission. Conclusions: Burn injuries predominantly affect working-age males and most frequently arise from domestic thermal accidents. Delayed presentation and inadequate first aid are common and influenced by behavioral, social, and demographic factors. Targeted public education, improved first aid practices, and timely healthcare-seeking are essential to reduce burn severity and improve patient outcomes.

24 April 2024 in Reports
Verified
Journal Article
Open access
PDF file
RORuxandra Bujor Oprita
Ruxandra Bujor Oprita
BOBogdan Oprita
Bogdan Oprita
ISIoana Adriana Serban
Ioana Adriana Serban
LSLidia Aurelia Stefan
Lidia Aurelia Stefan
MNMihai Neacsu
Mihai Neacsu
VEValentin Enache
Valentin Enache
Background: Lung cancer, particularly small-cell lung carcinoma (SCLC), often presents with respiratory symptoms. However, atypical manifestations including jaundice and abdominal pain can obscure the diagnosis, leading to challenges in early detection and treatment. Case Presentation: A 49-year-old male, with a history of smoking and diagnosed with Chronic Obstructive Pulmonary Disease (COPD), presented to the emergency department with a 3-day history of jaundice and a 3-week duration of mild abdominal pain. Initial investigations, including blood tests, showed hyperbilirubinemia and elevated lipase and amylase levels. An abdominal ultrasound was performed and revealed a hypoechoic, inhomogeneous mass in the head of the pancreas and multiple liver masses, suggesting a cephalo-pancreatic formation with liver metastasis. Further diagnostic procedures, including upper endoscopy and ERCP, followed by a TAP CT scan, identified a large mediastinal-pulmonary mass with invasion into major vessels and extensive metastasis. The immunohistochemical analysis of a duodenal ulcer biopsy confirmed a diagnosis of duodenal metastasis from a small-cell neuroendocrine lung carcinoma. Conclusion: Our case highlights that while rare, the possibility of metastatic spread should be included in the differential diagnosis when obstructive jaundice occurs in the context of high-risk factors for lung cancer.