Background/Objectives: Anxiety and depression result in a greater health burden; both can impact functionality and quality of life. This review aims to understand the association between anxiety, depression, functionality, and quality of life. Although three systematic reviews exist, one focuses on quality of life in depression and anxiety, while the others address functionality in depression and anxiety, with the former being more recent and the latter two being older. The association between these four variables will be explored. Methods: A literature search of MEDLINE with Full Text, CINHAL PLUS with Full Text, Psychology and Behavioral Sciences Collection, and Academic Search Complete was conducted from 1 January 2017 to 22 November 2022. Seven studies involving 2279 adults were included. Results: All studies analyzed the association between anxiety and/or depression with functionality and/or quality of life, in a population with a primary chronic condition. We found the higher functionality (return to work, no sedentary lifestyle, and no fatigue) and quality of life are, the lower the values of anxiety and depression will be. The HADS is a consensual instrument to access anxiety and depression, but the same cannot be said for assessing functionality and quality of life. Conclusions: The severity of the chronic disease and the loss of functionality and quality of life seem to increase psychological distress. This study highlights the importance of a multidisciplinary and holistic approach, focusing not only on clinical outcomes but also on overall well-being. Further longitudinal research is needed to support the association between these variables to draw more concrete conclusions with scientific evidence.

Family self-care emphasizes a family’s role in health promotion and protection, reflecting society’s views on health, illness, and human relationships. In families with children with an intellectual disability, where the child may lack self-care abilities, family self-care becomes crucial, highlighting that self-care needs exceed individual capacity and require family cooperation. Background/Objectives: This pilot study aims to explore the factors influencing family self-care and define attributes of its cognitive, psychosocial, physical, and behavioral domains in families with children with intellectual disabilities. Methods: A descriptive and correlational study with forty-four families was conducted. Exploratory analysis and linear regression analysis were estimated through the assumptions of the Gauss–Markov theorem (specifically homoscedasticity, normality, and model specification adequacy). Multicollinearity was also evaluated. Results: The significant family conditioning factors identified were family income, education level, degree of physical and functional dependence of the child, family household size, and social support. Socioeconomic, demographic, and health-related factors shaped self-care experiences. Conclusions: Family empowerment and the impact of disability are key elements in enabling self-care. Families reporting a greater impact of their child’s condition tended to feel less empowered, directly affecting their ability to perform daily self-care activities. The evidence suggests a pattern in which self-care activities might be reactive rather than proactive and focused on managing immediate challenges rather than long-term well-being. These insights can guide healthcare professionals, especially family nurses, toward a holistic, family-centered approach to supporting families with children with intellectual disabilities.

Background/Objectives: Family self-care (FSC) is increasingly recognized as a vital aspect of caregiving in pediatric chronic conditions. However, its development in families of children with intellectual disabilities (IDs) remains underexplored. This study aimed to examine how families construct and sustain FSC, and to identify factors that shape its development across four domains: physical, cognitive, psychosocial, and behavioral. Methods: A qualitative study was conducted using an abductive approach, combining inductive thematic analysis with a deductively applied theoretical framework. Semi-structured interviews were carried out with nine families of children with ID in southern Portugal. The children ranged in age from 4 to 15 years, and the parents were aged between 29 and 53 years. The data was analyzed using Bardin’s content analysis, supported by NVivo software, and organized according to the FSC framework. This study followed COREQ guidelines. Results: The families described a range of self-care strategies, including environmental adaptations, experiential learning, emotional regulation, and long-term planning. These practices were shaped by contextual factors such as access to healthcare, relationships with professionals, emotional support networks, and socioeconomic conditions. Four emergent conclusions illustrate how structural and relational dynamics influence FSC in daily caregiving. Conclusions: FSC is a dynamic, multidimensional process shaped by lived experience, family interactions, and systemic support. The findings support inclusive, family-centered care models and inform clinical practice, training, and policy in pediatric IDs.

A dissociative fugue occurs when an individual with dissociative amnesia wanders away from their familiar surroundings, maintaining self‑care and apparently normal behavior to observers, lasting from hours to months in a row. New identities can be assumed and even organized travel can occur. While dissociative amnesia by itself may have a prevalence of around 7.2%, dissociative fugue is a rare entity, with unknown prevalence, and there are few reports in the literature. In this article, we describe a case of dissociative fugue in a 34‑year old woman that lasted eight months. Dissociative amnesia with fugue remains an interesting topic for further research since it can present a diagnostic challenge, there are currently no evidence‑based pharmacological treatments and prognosis varies greatly between patients.