The school is a favorable environment for the development of interventions to prevent obesity. The objective of this systematic review is to evaluate the effects of school-based food and nutrition education interventions on adolescent food consumption. The literature search was conducted on databases: MEDLINE/PubMed, Embase, Scopus, ERIC, Science Direct, Web of Science, Cochrane, LILACS, and ADOLEC. The following research strategies were focused on: population (adolescents), intervention (food and nutrition education), outcome (food consumption), and study design (clinical trial). The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement guidelines were followed and all stages of this review were performed by two researchers and, when necessary, a third researcher resolved discrepancies. Included studies are randomized clinical trials (RCT). A total of 24 articles were included for review and 11 articles in meta-analysis. In the evaluation of the general effects, there was a significant effect (mean difference (MD) for fruit consumption (MD = 0.09, CI 0.05, 0.14) in serving/day; and for vegetables (MD = 0.59, IC 0.15, 1.03) at times/week. In the consumption of FV (fruits and vegetables), there was no significant effect (standardized mean difference (SMD) of interventions in their consumption (SMD = 0.00, 95% C1 −0.11, 0.11). The evidence available in this review and meta-analysis concludes that food and nutrition education interventions in schools presented favorable results in the food consumption of adolescents. Registered on the PROSPERO database (CRD42019116520).

The aim of this study was to analyze the evidence available in the literature about the effects of exercise on brain-derived neurotrophic factor levels in adolescents. The literature searches were conducted in PubMed, Embase, Scopus, ScienceDirect, Web of Science, SportDiscus, the Cochrane Central Register of Controlled Trials (CENTRAL) and CINAHL. Randomized controlled trials and non-randomized controlled trials performed with adolescents (10–19 years) who underwent different exercise programs and who evaluated BDNF levels before and after the intervention were included. We included six studies, four RCTs and two non-RCTs in the systematic review with a total of 407 adolescents. In two randomized trials and one non-RCT, the intervention groups showed significant improvements in BDNF levels compared with the control group. The results presented in the meta-analysis indicate that despite the positive effect in favor of the intervention, there were no significant differences (standardized mean difference 0.28 ng/mL, 95% confidence interval −0.28 to 0.85; p = 0.32, I² = 0%). The results presented in our review indicate that aerobic exercise programs practiced in moderate- or high-intensity are promising strategies to increase BDNF levels in adolescents. However, further studies are required to support this finding.

The aim of this study was to examine the associations of unprocessed red meat and processed meat consumption with cardiovascular disease (CVD) incidence and mortality, and the dose-response relatio...

Introdução: Em dezembro de 2019, a China foi assolada pela coronavirus disease (COVID-19), doença causada pelo novo coronavírus, o SARV-CoV-2. Devido ao alto poder de contágio, a Organização Mundial de Saúde declarou Emergência de Saúde Pública de Importância Internacional em 30 de janeiro de 2020. Em março do mesmo ano, mais de 100 países haviam registrado casos da nova doença, assim, devido à disseminação geográfica rápida, a Organização Mundial de Saúde declarou pandemia da COVID-19. Objetivo: Avaliar a adesão de hospitais públicos de ensino a um Modelo de Plano de Contingência para Infecção Humana pelo Novo Coronavírus publicado pela gestão central de uma empresa pública. Método: Estudo descritivo-analítico, utilizando o modelo elaborado e publicado como documento orientador para adequações do plano de contingência de cada um dos hospitais do estudo. Resultados: Após duas avaliações dos planos, 36 (94,7%) hospitais apresentaram conformidade superior a 70,0%, sendo que quatro (10,5%) deles apresentaram 100,0% de conformidade com o modelo. A média de adesão dos hospitais ao modelo cresceu de 82,3% na 1ª avaliação, para 91,3% na segunda avaliação, um aumento percentual igual a 11,0%. Todos os hospitais do estudo mantiveram ou aumentaram seus percentuais de adesão. Conclusões: A pesquisa demonstrou a potencialidade do modelo em orientar as instituições na elaboração e aprimoramento dos seus planos. Considerando os resultados positivos dessa experiência e a escassez histórica de leitos hospitalares, especialmente aqueles com suporte ventilatório, recomenda-se que as autoridades sanitárias brasileiras possam investir tempo e recursos na elaboração de documentos orientadores que auxiliem gestores na reorganização e resposta dos hospitais em situações de crise.

Bioactive peptides derived from native proteins modulate physiological processes in the metabolic pathways. Given that multiple protocols in the literature mimic the digestion of dietary components, gathering studies that use such models directed at protein digestion processes is critical. This systematic review aimed to gather evidence that adopted adequate experimental models to simulate human protein digestion. The databases searched were PubMed, Web of Science, ScienceDirect, Embase, Virtual Health Library, and Scopus. A total of 1985 articles were found, resulting in 20 eligible in vitro studies. The Office of Health Assessment and Translation was used to evaluate methodological quality. Seven studies used plant-based protein sources, twelve used animal protein sources, and one used both. The duration of the oral phase varied, although 60% of the studies employed a protein digestion period of 120 min. Amylase, pepsin, and pancreatin enzymes were utilized in 40% of the studies, with pH levels of 7, 3, and 7, respectively, during the oral, gastric, and intestinal phases. The INFOGEST harmonized static model was adopted by 65% of the studies; INFOGEST is the most effective model for simulating gastrointestinal protein processes in humans and can be used to answer several research questions because it describes experimental conditions close to the human physiological situation.