The use of synthetic additives as setting retarders and plasticisers has over the past years become a standard practice in mortar mixtures, despite their potential adverse environmental effects. Since antiquity, man has used organic additives ranging from plant and animal-derived extracts, to improve the setting properties of mortars. These practices are slowly being revived and investigated scientifically to promote the use of materials with lower impacts on the environment. Amongst the many different types of plant-derived extracts that have been used as mortar and concrete additives, the prickly pear (Opuntia ficus-indica) mucilage extract, is popular in Meso-and South-America. The scientific basis of these additives lies in the hydrating properties of the mucilage polysaccharide complex. The purpose of this research was to prepare Opuntia ficus-indica (OFI) extracts in different forms and incorporate them in cement pastes and mortar mixtures by either replacing the water in the mixture with OFI mucilage or by replacing the cement in the mixture with OFI lyophilised powder. The inclusion of Opuntia ficus-indica additives in cement-based mortars increased their performance in terms of strength for both water and powder replacements. Conversely results in cement pastes showed that Opuntia ficus-indica additives weakened the cement paste samples in terms of strength in both water and power replacements. Results for both cementbased mortars and cement pastes showed an increase in setting time for both water and powder replacements, indicating that Opuntia ficus-indica additives could be potentially used as retarding agents.

Herein we present eight ferrocenyl 4-amino-1,8-naphthalimides. Designed as fluorescent logic gates for acidity and oxidisability, the molecules have been repurposed as anti-proliferation and cellular imaging agents. The compounds were studied in vitro against MCF-7 and K562 cancer cell lines by the MTT method. Compounds with protonable secondary amines tended to exhibit greater cytotoxicity than those with tertiary amines. Compounds with no measurable GI₅₀ values within a 24 hour time window, as well as at shorter exposure times, may be suitable as fluorescent cellular imaging probes.

Goals number 2, 11 and 12 of the 17 sustainable development goals, enacted by the United Nations as part of the 2030 Agenda for sustainable development, aim to end hunger as a priority, create sustainable cities and above all encourage responsible consumption and production. With increasing world population and higher demand for food, we need to find ways of producing cheap sources of protein and lipid that may in turn be used as animal or aquaculture feed. A multitrophic system involving mealworm larvae (MWL, Tenebrio molitor) and black soldier fly larvae (BSFL, Hermetia illucens) was developed to transform fruit and vegetable kitchen waste into usable biomass. MWL, fed mainly on kitchen waste, reached an average prepupal length of 2.4 cm, fresh weight of 0.12 g and dry matter protein and lipid contents of 44.2% and 16.5% respectively, with an average specific growth rate (SGR) of 2.2%/day and a feed conversion ratio (FCR) of 7.9. Conversely, BSFL fed on a variety of feeds, including MWL frass, kitchen waste and oats, had an average prepupal length of 1.3 cm, fresh weight of 0.16 g and dry matter protein and lipid contents of 41.4% and 26.3% respectively, with an average SGR and FCR of 4.3%/day and 8.9 respectively. The BSFL fed MWL frass obtained some of highest SGR and lowest FCR values, with one group achieving 7.5%/day and 2.9 respectively. This investigation has demonstrated the feasibility of a multi-trophic production system using kitchen waste to feed MWL whose frass was in turn used to feed BSFL thereby producing protein- and lipid-rich biomass that can serve as animal or aquaculture feed.

(1) Background: Diabetes mellitus is a chronic metabolic disease with a rising global prevalence. Mulberry leaf (ML), a traditional medicinal and edible plant, possesses notable hypoglycemic effects and has a long history of usage. This review aims to systematically consolidate the research progress on the hypoglycemic constituents derived from ML, including their chemical structure, extraction methods, quality analysis techniques, and hypoglycemic mechanisms. (2) Methods: Adhering to the Preferred Reporting Items for Systematic Reviews (PRISMA 2020) guidelines, a comprehensive literature search was conducted using Web of Science and PubMed databases to find relevant studies published between 2015 and 2025. (3) Results: This review evaluates both conventional and modern techniques such as water extraction, ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), and enzyme-assisted extraction (EAE), highlighting their advantages and limitations when applied on ML. Additionally, this review examines the analytical techniques applied in the quality control of ML and its constituents. This is complemented by a summary of hypoglycemic mechanisms, focusing on the inhibition of oxidative stress, amelioration of insulin resistance, regulation of related enzyme activity, and modulation of gut microbiota. (4) Conclusions: ML demonstrates considerable potential for treating diabetes. However, further studies are needed for new drug discovery based on new ML-derived bioactive constituents, highly efficient extraction methods, quality analysis techniques, and underlying mechanisms.