Jasmonates (JAs) are crucial phytohormones governing plant growth and defense against stresses. This review synthesizes the intricate molecular mechanisms underlying JA crosstalk with key hormones: auxin (AU), gibberellin (GA), abscisic acid (ABA), ethylene (ET), brassinosteroids (BRs), strigolactones (SLs), and salicylic acid (SA). We focus on interactions during development and stress adaptation, highlighting how these range from synergistic (e.g., JA-ABA/ET in defense, JA-AU in root growth) to antagonistic (e.g., JA-SA in pathogen response, JA-GA/BRs in growth processes). Central to this crosstalk are key regulatory nodes like the MYC2 transcription factor and JAZ repressor proteins, which integrate signals through transcription factor networks, targeted protein degradation, and post-translational modifications. By elucidating these molecular pathways, our review establishes a framework for understanding the complex regulatory logic of hormone interactions. Furthermore, it offers insights for the strategic engineering of hormone signaling (e.g., modulating JAZ stability or MYC2 activity) to enhance crop resilience to environmental challenges.