Mireille B Toledano

Dr. Mireille B Toledano


Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2022 in Environment International
Verified
Journal Article
Open access
RTRhiannon Thompson
Rhiannon Thompson
RSRachel B. Smith
Rachel B. Smith
YKYasmin Bou Karim
Yasmin Bou Karim
CSChen Shen
Chen Shen
KDKayleigh Drummond
Kayleigh Drummond
MTMireille B Toledano
Mireille B Toledano
This systematic review provides a comprehensive synthesis of recent epidemiological evidence that environmental noise negatively impacts human cognition. We update a prior review with recent publications (PROSPERO CRD42019151923). The strength of evidence for associations was assessed using the GRADE (Grading of Recommendations, Assessment, Development and Evaluations) framework. We also conducted random-effects meta-analyses where suitable. 16 studies were identified and reviewed in tandem with 32 studies previously reviewed by Clark & Paunovic (2018). A meta-analysis from 3 studies found that reading comprehension scores in quiet classrooms were 0.80 (95% confidence interval: 0.40; 1.20) points higher than children in noisier classrooms. Meta-analysis of the impact of 1 dB (dB) increase in environmental noise on reading and language abilities gave a pooled beta coefficient of -0.11(95% confidence interval: -0.32; 0.10). A meta-analysis of Odds Ratios (OR) from 3 studies found higher odds of cognitive impairment in people aged 45 + with higher residential noise exposure (OR 1.40, 95% CI: 1.18;1.61). After qualitative synthesis of remaining studies, there was high quality evidence for an association between environmental noise and cognitive impairment in middle-to-older adults, moderate quality evidence for an association between aircraft noise and reading and language in children, and moderate quality evidence against an association between aircraft noise and executive functioning in children. Generally the literature was supportive for other cognitive outcomes, but with low or very low-quality evidence. The evidence so far suggests that noise exposure is associated with cognition, but more good quality research using standardised methodology is required to corroborate these results and to allow for precise risk estimation by larger meta-analyses. There is also a need for more research with older teenagers and young-to-middle aged adults, on the synergistic effects of noise and air pollution, and in Africa, Central and South America, South Asia and Australasia.

1 March 2019 in Environment International
Verified
Journal Article
Open access
Michael MirekuMichael Mireku
Michael Mireku
MBMary M. Barker
Mary M. Barker
JMJulian Mutz
Julian Mutz
IDIroise Dumontheil
Iroise Dumontheil
MTMichael Thomas
Michael Thomas
MTMireille B Toledano
Mireille B Toledano
The present study investigates the relationship between night-time screen-based media devices (SBMD) use, which refers to use within 1 h before sleep, in both lit and dark rooms, and sleep outcomes and health-related quality of life (HRQoL) among 11 to 12-year-olds. We analysed baseline data from a large cohort of 6616 adolescents from 39 schools in and around London, United Kingdom, participating in the Study of Cognition Adolescents and Mobile Phone (SCAMP). Adolescents self-reported their use of any SBMD (mobile phone, tablet, laptop, television etc.). Sleep variables were derived from self-reported weekday and/or weekend bedtime, sleep onset latency (SOL) and wake time. Sleep quality was assessed using four standardised dimensions from the Swiss Health Survey. HRQoL was estimated using the KIDSCREEN-10 questionnaire. Over two-thirds (71.5%) of adolescents reported using at least one SBMD at night-time, and about a third (32.2%) reported using mobile phones at night-time in darkness. Night-time mobile phone and television use was associated with higher odds of insufficient sleep duration on weekdays (Odds Ratio, OR = 1.82, 95% Confidence Interval, CI [1.59, 2.07] and OR = 1.40, 95% CI [1.23, 1.60], respectively). Adolescents who used mobile phones in a room with light were more likely to have insufficient sleep (OR = 1.32, 95% CI [1.10, 1.60]) and later sleep midpoint (OR = 1.64, 95% CI [1.37, 1.95]) on weekends compared to non-users. The magnitude of these associations was even stronger for those who used mobile phones in darkness for insufficient sleep duration on weekdays (OR = 2.13, 95% CI [1.79, 2.54]) and for later sleep midpoint on weekdays (OR = 3.88, 95% CI [3.25, 4.62]) compared to non-users. Night-time use of mobile phones was associated with lower HRQoL and use in a dark room was associated with even lower KIDSCREEN-10 score (β = -1.18, 95% CI [-1.85, -0.52]) compared to no use. We found consistent associations between night-time SBMD use and poor sleep outcomes and worse HRQoL in adolescents. The magnitude of these associations was stronger when SBMD use occurred in a dark room versus a lit room.

5 December 2017 in BMJ
Verified
Journal Article
Open access
PDF file
RSRachel B Smith
Rachel B Smith
DFDaniela Fecht
Daniela Fecht
JGJohn Gulliver
John Gulliver
SBSean D Beevers
Sean D Beevers
DDDavid Dajnak
David Dajnak
MTMireille B Toledano
Mireille B Toledano
Objective To investigate the relation between exposure to both air and noise pollution from road traffic and birth weight outcomes. Design Retrospective population based cohort study. Setting Greater London and surrounding counties up to the M25 motorway (2317 km2), UK, from 2006 to 2010. Participants 540 365 singleton term live births. Main outcome measures Term low birth weight (LBW), small for gestational age (SGA) at term, and term birth weight. Results Average air pollutant exposures across pregnancy were 41 μg/m3 nitrogen dioxide (NO2), 73 μg/m3 nitrogen oxides (NOx), 14 μg/m3 particulate matter with aerodynamic diameter <2.5 μm (PM2.5), 23 μg/m3 particulate matter with aerodynamic diameter 13.8 μg/m3during pregnancy. Conclusions The findings suggest that air pollution from road traffic in London is adversely affecting fetal growth. The results suggest little evidence for an independent exposure-response effect of traffic related noise on birth weight outcomes.

1 August 2014 in Environment International
Verified
Journal Article
Closed access
DADanielle C. Ashworth
Danielle C. Ashworth
PEPaul Elliott
Paul Elliott
MTMireille B Toledano
Mireille B Toledano

23 November 2022 in Science of The Total Environment
Verified
Journal Article
Closed access
RTRhiannon Thompson
Rhiannon Thompson
RSRachel B. Smith
Rachel B. Smith
YKYasmin Bou Karim
Yasmin Bou Karim
CSChen Shen
Chen Shen
KDKayleigh Drummond
Kayleigh Drummond
MTMireille B Toledano
Mireille B Toledano

19 July 2021 in Nature Sustainability
Verified
Journal Article
Closed access
PDF file
MMMikaël J. A. Maes
Mikaël J. A. Maes
MPMonica Pirani
Monica Pirani
EBElizabeth R. Booth
Elizabeth R. Booth
CSChen Shen
Chen Shen
BMBen Milligan
Ben Milligan
MTMireille B Toledano
Mireille B Toledano