Constantina A. Jacovides

Mrs. Constantina A. Jacovides


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 June 2024 in Medicina
Verified
Journal Article
Open access
PDF file
Antonios DakanalisAntonios Dakanalis
Antonios Dakanalis
GVGavriela Voulgaridou
Gavriela Voulgaridou
OAOlga Alexatou
Olga Alexatou
Sousana PapadopoulouSousana Papadopoulou
Sousana Papadopoulou
CJConstantina A. Jacovides
Constantina A. Jacovides
CONSTANTINOS GIAGINISCONSTANTINOS GIAGINIS
CONSTANTINOS GIAGINIS
Background and Objectives: Overweight and obesity are growing public health challenges, particularly concerning young adults. University life presents a unique set of stressors that may influence weight management alongside sleep quality. In this cross-sectional study, we aimed to investigate the association between overweight or obesity, stress, and sleep quality in a large sample of Greek university students. Materials and Methods: The study recruited 2116 active students from across various Greek universities. Participants completed questionnaires on sociodemographics, academic performance, and physical activity levels using the International Physical Activity Questionnaire (IPAQ). Stress and sleep quality were assessed using the Perceived Stress Scale (PSS) and the Pittsburgh Sleep Quality Index (PSQI), respectively. Body weight and height were directly measured to calculate Body Mass Index (BMI). Results: Our analysis of 2116 Greek university students revealed significant associations between various factors and overweight/obesity. Compared to their rural counterparts, young adults in urban areas had an 88% higher prevalence of overweight/obesity (p = 0.0056). Regular smokers were twice as likely to be overweight or obese (p = 0.0012). Notably, those with low physical activity levels displayed a more than two-fold increased risk (p = 0.0008) compared to those with moderate or high activity levels. Similarly, students with moderate or high perceived stress levels had a more than two-fold prevalence of overweight/obesity compared to those with low stress (p = 0.0005). Inadequate sleep quality was also associated with an 86% higher risk of overweight/obesity (p = 0.0007). Interestingly, good academic performance showed a 57% greater prevalence of overweight/obesity compared to very good/excellent performance (p = 0.0103). Conclusions: Our findings reveal that perceived stress and poor sleep quality are significant risk factors for overweight and obesity in this young adult population.

21 May 2024 in Nutrients
Verified
Journal Article
Open access
PDF file
MCMaria Chrysafi
Maria Chrysafi
CJConstantina A. Jacovides
Constantina A. Jacovides
Sousana PapadopoulouSousana Papadopoulou
Sousana Papadopoulou
EPEvmorfia Psara
Evmorfia Psara
TVTheofanis Vorvolakos
Theofanis Vorvolakos
CONSTANTINOS GIAGINISCONSTANTINOS GIAGINIS
CONSTANTINOS GIAGINIS
Background: The ketogenic diet (KD) has been highly developed in the past for the treatment of epileptic pathological states in children and adults. Recently, the current re-emergence in its popularity mainly focuses on the therapy of cardiometabolic diseases. The KD can also have anti-inflammatory and neuroprotective activities which may be applied to the prevention and/or co-treatment of a diverse range of psychiatric disorders. Purpose: This is a comprehensive literature review that intends to critically collect and scrutinize the pre-existing research basis and clinical data of the potential advantageous impacts of a KD on stress, anxiety, depression, schizophrenia and bipolar disorder. Methods: This literature review was performed to thoroughly represent the existing research in this topic, as well as to find gaps in the international scientific community. In this aspect, we carefully investigated the ultimate scientific web databases, e.g., PubMed, Scopus, and Web of Science, to derive the currently available animal and clinical human surveys by using efficient and representative keywords. Results: Just in recent years, an increasing amount of animal and clinical human surveys have focused on investigating the possible impacts of the KD in the prevention and co-treatment of depression, anxiety, stress, schizophrenia, and bipolar disorder. Pre-existing basic research with animal studies has consistently demonstrated promising results of the KD, showing a propensity to ameliorate symptoms of depression, anxiety, stress, schizophrenia, and bipolar disorder. However, the translation of these findings to clinical settings presents a more complex issue. The majority of the currently available clinical surveys seem to be moderate, usually not controlled, and have mainly assessed the short-term effects of a KD. In addition, some clinical surveys appear to be characterized by enormous dropout rates and significant absence of compliance measurement, as well as an elevated amount of heterogeneity in their methodological design. Conclusions: Although the currently available evidence seems promising, it is highly recommended to accomplish larger, long-term, randomized, double-blind, controlled clinical trials with a prospective design, in order to derive conclusive results as to whether KD could act as a potential preventative factor or even a co-treatment agent against stress, anxiety, depression, schizophrenia, and bipolar disorder. Basic research with animal studies is also recommended to examine the molecular mechanisms of KD against the above psychiatric diseases.

Verified
Journal Article
Open access
PDF file
CJConstantina A. Jacovides
Constantina A. Jacovides
Sousana PapadopoulouSousana Papadopoulou
Sousana Papadopoulou
Eleni PavlidouEleni Pavlidou
Eleni Pavlidou
Antonios DakanalisAntonios Dakanalis
Antonios Dakanalis
OAOlga Alexatou
Olga Alexatou
CONSTANTINOS GIAGINISCONSTANTINOS GIAGINIS
CONSTANTINOS GIAGINIS
Background: In recent decades, the incidence of depression has gradually increased in the general population globally. Depression is also common during gestation and could result in detrimental gestational complications for both the mother and the fetus. The survey presented aimed to evaluate whether pregnant women’s perinatal depression could be associated with socio-demographic, anthropometry and lifestyle factors, and perinatal and postnatal outcomes. Methods: This is a cross-sectional survey conducted on 5314 pregnant women. Socio-demographic and lifestyle factors were recorded by relevant questionnaires via face-to-face interviews. Anthropometric parameters were measured by qualified personnel. Perinatal depressive symptomatology status was evaluated by Beck’s Depression Inventory (BDI-II) questionnaire. Results: Depressive symptoms throughout gestation were found in 35.1% of the enrolled women. Perinatal depression was significantly associated with lower educational and economic level, pre-pregnancy regular smoking and reduced levels of Mediterranean diet adherence levels, a higher prevalence of gestational diabetes and preterm birth, as well as a higher incidence of delivering by caesarean section and abnormal childbirth weight. Perinatal depression was also significantly associated with a higher prevalence of maternal postpartum depression and lower prevalence of exclusive breastfeeding practices, as well as with a higher incidence of childhood asthma. Conclusions: Pregnant women’s perinatal depression appears to be associated with various socio-demographic, anthropometry, and lifestyle characteristics and with a higher frequency of several adverse pregnancy complications. The present findings emphasize the importance of pregnant women’s perinatal mental health, highlighting the need to develop and apply public strategies and policies for psychological counseling and support of future mothers to minimize probable risk factors that may trigger perinatal depression. Novel well-organized, follow-up surveys of enhanced validity are highly recommended to establish more definitive conclusions.

28 October 2024 in COVID
Verified
Journal Article
Open access
PDF file
MMMaria Mentzelou
Maria Mentzelou
Sousana PapadopoulouSousana Papadopoulou
Sousana Papadopoulou
CJConstantina A. Jacovides
Constantina A. Jacovides
Antonios DakanalisAntonios Dakanalis
Antonios Dakanalis
OAOlga Alexatou
Olga Alexatou
CONSTANTINOS GIAGINISCONSTANTINOS GIAGINIS
CONSTANTINOS GIAGINIS
Background: There has been recent evidence to suggest that people who suffer from eating disorders (EDs) or other eating behavior disturbances, such as emotional eating (EE), are particularly vulnerable post-COVID-19. This narrative literature review aims to comprehensively analyze and scrutinize the existing clinical studies regarding the effects of the COVID-19 pandemic on people with EDs or EE. Moreover, due to the COVID-19 pandemic, it is very important to find out whether a person’s emotional state may lead them to wrongly confront their emotional behavior with food consumption. Methods: A thorough search of several databases (PubMed, Scopus, Web of Science, Public Library of Science, Google Scholar, CINAHL Complete, PsycINFO, and Academic Search Complete) was performed to identify available clinical studies on the COVID-19 pandemic published between 2020 and 2024 using relevant keywords. Results: There is substantial evidence that the COVID-19 pandemic exerted negative effects on persons suffering from EDs, including those who are symptomatic, those who are in remission, and those with an EE behavior. Characteristically, people diagnosed with anorexia nervosa (AN), bulimia nervosa (BN), or binge eating disorder (BED) showed considerable symptomatic worsening after the first wave of the COVID-19 pandemic. Clinical studies investigating the effects of the COVID-19 pandemic on persons suffering from EE have also clearly demonstrated that their mood disturbances negatively affected their eating behaviors. These studies have also shown that vulnerable people were at greater risk of EE development and progression during the COVID-19 pandemic. Conclusion: The COVID-19 pandemic seems to have exerted a significant deleterious effect on people who have a history of suffering from EDs or EE. The COVID-19 pandemic has been related to the frequency of dysfunctional eating behaviors, thus decreasing therapeutic intervention efficiency in people with EDs as well as in those with disturbed eating behaviors such as EE. In this aspect, further clinical studies are strongly recommended to investigate the exact effects of the COVID-19 pandemic as well as to explore their potential long-term deleterious complications in the post-pandemic period. Public strategies and policies should be applied to provide special healthcare for this group of patients.

17 December 2024 in Pediatric Reports
Verified
Journal Article
Open access
PDF file
CJConstantina A. Jacovides
Constantina A. Jacovides
APAgathi A Pritsa
Agathi A Pritsa
MCMaria Chrysafi
Maria Chrysafi
Sousana PapadopoulouSousana Papadopoulou
Sousana Papadopoulou
MKMaria Kapetanou
Maria Kapetanou
CONSTANTINOS GIAGINISCONSTANTINOS GIAGINIS
CONSTANTINOS GIAGINIS
Background: Mediterranean diet (MD) constitutes a commonly examined dietary model. It includes a plethora of bioactive ingredients with strong antioxidant, anti-inflammatory, antithrombotic and anticancer properties. Several substantial studies support strong evidence that MD can exert preventing actions against human morbidity and mortality, promoting human well-being and quality of life. The present study aims to evaluate whether childhood MD compliance may be associated with socio-demographic, anthropometric, and lifestyle factors in children at the age of 6–9 years. Methods: This is a cross-sectional survey on 3875 children aged 6–9 years old with their matched mothers. Qualified questionnaires were used to evaluate and collect by one-to-one interviews with trained professionals the above data. Results: Elevated MD adherence was observed only in 22.2% of the enrolled children, while 37.5% of children maintained intermediate MD adherence and 40.3% of children adopted lower MD levels. Children MD compliance was related at an independent manner with maternal education level, childhood anthropometric factors such as Body Mass Index (BMI), Waist circumference to Height ratio (WtHR), quality of life, and exclusively breastfeeding behaviors after adjusting for several possible confounders (p ˂ 0.05). Conclusions: Elevated MD adherence of children aged 6–9 years old showed a lower obesity of overweight/obesity, including abdominal obesity. A higher maternal educational status and adopting exclusively breastfeeding practices were associated with greater levels of children’s MD adherence, promoting their quality of life and well-being. Based on the present results, future prospective surveys need to be performed to evaluate if there is a causality relation concerning this topic.

14 February 2025 in Diseases
Verified
Journal Article
Open access
PDF file
MMMaria Mentzelou
Maria Mentzelou
Sousana PapadopoulouSousana Papadopoulou
Sousana Papadopoulou
EPEvmorfia Psara
Evmorfia Psara
TVTheofanis Vorvolakos
Theofanis Vorvolakos
CJConstantina A. Jacovides
Constantina A. Jacovides
CONSTANTINOS GIAGINISCONSTANTINOS GIAGINIS
CONSTANTINOS GIAGINIS
Background/Objectives: Emotional eating is an eating behavior that is influenced by behaviors, stress, emotions, and individual feelings in relation to eating. For many decades, studies have shown that mental health is the complex outcome of numerous biological, psychological, and social factors, involving contextual factors beyond the individual. Aim: The objective of this study is to evaluate the interconnections between emotional eating and sociodemographic and anthropometric characteristics and lifestyle factors. Methods: This is a cross-sectional study conducted on 328 adults aged between 18 and 75 years. Relevant questionnaires were utilized to evaluate sociodemographic and anthropometric parameters and types of feeding and the expression of emotional food consumption (The Three-Factor Eating Questionnaire). Results: According to the analyses above, negative correlations between the emotional eating score and waist circumference and Body Mass Index (BMI) were noted. Furthermore, men were more likely to eat emotionally than women. According to a univariable regression analysis, it was also shown that there was an inverse relationship with age up to 35.92 years and a positive relationship for age > 35.92 years. In addition, an inverse relationship with a decrease in the emotional eating score was found with a BMI up to <49.32 kg/m2. Conclusion: Our findings have emphasized the importance of performing large, prospective, well-designed, randomized, interventional, clinical trials to generate data indicating improvements in eating behavior. Moreover, in future studies the researchers must indicate which assessment tool for emotional eating they will use.