The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that mimics the physiological state of fasting. The potential therapeutic effects in many chronic conditions have led to the gaining popularity of the KD. The KD has been demonstrated to alleviate inflammation and oxidative stress, modulate the gut microbiota community, and improve metabolic health markers. The modification of these factors has been a potential therapeutic target in serious mental illness (SMI): bipolar disorder, major depressive disorder, and schizophrenia. The number of clinical trials assessing the effect of the KD on SMI is still limited. Preliminary research, predominantly case studies, suggests potential therapeutic effects, including weight gain reduction, improved carbohydrate and lipid metabolism, decrease in disease-related symptoms, increased energy and quality of life, and, in some cases, changes in pharmacotherapy (reduction in number or dosage of medication). However, these findings necessitate further investigation through larger-scale clinical trials. Initiation of the KD should occur in a hospital setting and with strict care of a physician and dietitian due to potential side effects of the diet and the possibility of exacerbating adverse effects of pharmacotherapy. An increasing number of ongoing studies examining the KD’s effect on mental disorders highlights its potential role in the adjunctive treatment of SMI.

Background and Objectives: Challenges and threats to global security and the growing demands of today’s society lead to significantly increased exposure to stress. Stress can negatively affect numerous physiological processes, including metabolic changes. An unhealthy lifestyle might intensify this disruption. The aim of the systematic review was to establish the effect of psychological stress on metabolic and anthropometric factors in healthy individuals. Materials and Methods: The study was conducted according to the PRISMA guidelines; and the risk of bias (ROB) assessment was based on the Newcastle–Ottawa Scale (NOS). A literature search of the MEDLINE/PubMed database was conducted using specific search terms. Results: We identified 32 articles meeting the inclusion criteria for the review with the different experimental designs and aims. Most of the papers were at high ROB. The included studies were conducted in groups of adults and children/teenagers. The most-often-applied tool to measure stress severity was the Perceived Stress Scale (PSS). Twenty-two studies analyzed the connection between stress and body composition, and bioimpedance analysis (BIA) was the most often used method. For biological parameters, the most frequently analyzed was cortisol (n = 9). The other examined factors included glucose, insulin, parameters related to food intake regulation, carbohydrates, lipid metabolism, inflammation, and oxidative stress. The included studies were incompliance in relation to the assessment method and type of assessed biological fluids. Conclusions: The vast majority of studies do not support the effect of chronic distress on anthropometric measurements and biological markers levels. However, many of them suggest adverse, synergistic effects of unhealthy lifestyle patterns and the stress on the examined variables. Further experiments should implement a similar and repeatable methodology.

Introduction: Since implementation, electroconvulsive therapy has remained very effective treatment in psychiatry. The aim of this study is to present the differences in its use in medical practice around the world. The range of diseases in which ECT is most commonly used and the frequency of its use in different countries were compared with special attention to the differences between highly and poorly developed countries. Material and method: Review of literature by searching PubMed and Google Scholar databases using the keywords: indications of ECT, frequency of ECT use for papers published from 1991 to 2021. Results: Among the diseases for which electroconvulsive therapy is used worldwide, major depression dominates, while in Asia and Africa this therapy is used in schizophrenia. In Latin America it is used primarily for schizophrenia and bipolar disorder. In Poland, it is used for depression, bipolar disorder, and fewer for schizophrenia. The highest rate of people treated with therapy per 100,000 population is found in countries such as the USA (51), Canada (23.2-25.6), Australia (37.85), Sweden (41), Finland (23), Slovakia (29.2), Estonia (27.8) and Belgium (47). Conclusions: There is a relationship between the range of diseases most frequently treated with ECT, the frequency of use and the level of country development. In the high developed countries, ECT is used mainly in major depression, in less developed countries more frequent treatment of schizophrenia may be determined by the high cost of medications and limited availability of hospital beds. The highest rates of use of this therapy are found in more developed countries.

Introduction and purpose Proper nutrition and appropriately chosen supplementation during pregnancy significantly ensure a healthy pregnancy and fetal development. Both nutrient deficiencies and excesses can have negative health effects on both the mother and the child. This article discusses specific active substances that are particularly important in supplementation of pregnant women. The aim of the study is to describe the current state of knowledge about the importance of adequate supply of vitamins and minerals compounds during pregnancy, in order to increase women's awareness and encourage improvement in dietary habits. Material and methods of research For this study, a review of literature available on Google Scholar and PubMed was conducted. From the analysis, studies published before 2017 were excluded. State of knowledge Based on the current state of knowledge, we know that the nutrition of pregnant women undergoes partial modifications. To ensure a healthy pregnancy, there is an increased energy demand in the body, making appropriate weight gain crucial. Routine use of multivitamin supplements is not recommended for pregnant women, as a balanced diet should be the primary source of macronutrients, micronutrients, and vitamins. Key components that are used in supplementation for pregnant women in specific cases include iron, folic acid, vitamin D, DHA acids, and iodine. Conclusions This work emphasizes the significant impact of proper nutrition and appropriately selected supplementation in pregnant women on reducing the risk of various pregnancy complications and fetal developmental disorders. It highlights the importance of deficiencies and excesses of vitamins and minerals compounds in the diet of women during the preconception period, all trimesters of pregnancy and lactation.

Human sexuality is a component of a holistic being, a biopsychosocial state, defined by the World Health Organization as health. It is manifested in aspects of relationship, desire, sexual behavior, orientation, among others. Every year, more and more reports say that the age of sexual initiation is shifting towards younger years. It is worth noting that, according to analyses, the sexuality of the young does not differ from that of the 20th century. In boys, the motivation to engage in sexual activity is usually lust, in girls it is love and emotion. This condition is influenced by many factors: biological, genetic, environmental, family, as well as psychological factors like personality and temperament. The health care system should promote appropriate sexual behavior, along with sex education and awareness of the consequences of risky behavior, including those related to venereal aspects.

Cytomegalovirus is one of the most widespread DNA viruses, with 90% of women of childbearing age in Poland infected with it. Infection poses a risk to the mother as well as the fetus, as the virus can cross the placenta and damage the fetus. The purpose of this paper is to review scientific publications from 2017-2022, which describe the course of cytomegalovirus infection in pregnant women, the risks to the mother and fetus associated with the infection, methods of diagnosing the infection in the pregnant woman and the fetus, as well as treatment of cytomegalovirus infection and directions for vaccine research. The most common complications of congenital cytomegalovirus infection include hearing loss, mental developmental delays and miscarriage. The infection can be detected in the pregnant woman by immunological testing, while polymerase chain reaction is used in the fetus and newborn. Early detection of infection in a pregnant woman allows the implementation of treatment which includes ganciclovir, valganciclovir, acyclovir and valacyclovir. A vaccine against cytomegalovirus has not been developed. Particularly important in the prevention of infection is to conduct educational activities regarding the routes of transmission of the virus and the consequences of congenital infection for the fetus. Cytomegalovirus infections among pregnant women. It is important to monitor fetal development and possibly diagnose for congenital CMV infection in case of abnormalities, and the best diagnostic method is polymerase chain reaction testing. For the treatment of congenital CMV infection, acyclovir and valacyclovir are preferred, and therapy should be implemented for specific indications. Attention should be paid to educating women about infections caused by cytomegalovirus.