To describe the first case of ceftriaxone-related haemolysis in a patient with congenital nephrotic syndrome (CNS). Severe haemolysis caused by an immune reaction to ceftriaxone has mostly been described in patients with underlying haematological or immune dysfunction. The authors present a 20-month-old boy with CNS of the Finnish type with several previous severe infections treated with ceftriaxone, admitted for suspected sepsis. Following ceftriaxone administration he developed shock secondary to an acute haemolytic reaction, with severe anaemia. Hypersensitivity to ceftriaxone was documented through positive agglutination tests. Onset of haemolysis following ceftriaxone administration, particularly in a patient previously exposed to the drug, must raise the suspicion of a possible immune reaction.

Background: Research on post-traumatic growth (PTG) and HIV is scarce and the relationship between PTG and stigma is controversial. Group psychotherapeutic interventions to facilitate PTG in clinical samples are effective but none exist to simultaneously decrease stigma in the HIV population. The main objective was to evaluate the effectiveness of an intervention in increasing PTG and decreasing stigma in HIV, as well as to explore relationships between the variables. Methods: Quasi-experimental design with a sample of 42 HIV-positive adults (M = 46.26, SD = 11.90). The experimental group (EG) was subjected to a 9-week group intervention. Instruments: CBI, PTGI-X, PSS-10, HIV stigma, emotional expression, HIV stress indicators, HIV literacy, and skills. Multiple linear regression analysis was performed to assess the relationship between the variables. Results: There was an increase in PTG and a significant decrease in stigma in all domains and subscales in the EG. Compared to the control group, stigma (t₍₄₂₎ = −3.040, p = 0.004) and negative self-image (W = −2.937, p = 0.003) were significant, showing the efficacy of the intervention. Discussion: The intervention demonstrated success in facilitating PTG, attesting that in order to increase PTG, personal strength, and spiritual change, it is necessary to reduce stigma and negative self-image. The research provides more information on group interventions for PTG in HIV, relationships between variables, and population-specific knowledge for professionals.

The (in)ability to accept and find meaning in the loss of a loved one can lead to the development of prolonged grief disorder (PGD), a return to normal level of functioning, or posttraumatic growth (PTG). This study aims to examine the factors that can predict PGD and PTG, in order to understand the differences between these two paths of adjustment. 269 bereaved adults participated in completing a questionnaire on PGD, PTG, presence and search for meaning, spirituality, relationship quality, depression, and anxiety. Results show that there are common factors that positively predict both intense grief and posttraumatic growth, such as the impact of the event, spirituality, and a relationship of proximity. The final model explained 68% and 32% of the variance of symptoms of PGD and PTG, respectively. This study highlights the importance of examining PGD and PTG together to understand better what distinguishes an adaptive from a maladaptive adjustment to grief.