Selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat depression. SSRIs are classified as fluoxetine, paroxetine, escitalopram, citalopram, sertraline, and fluvoxamine. Several methods have been published for the determination of SSRI drugs in pharmaceuticals, biological materials and environmental samples. This review covers the analytical methods described in the literature for the determination of SSRIs and their main metabolites or some compounds belonging to the same SSRI group. The analytical methods are generally chromatography based methods coupled to different detectors, electroanalytical methods, capillary zone electrophoretic methods, and spectrometric methods.

In this study, the removal of Reactive Blue 19 dyestuffs in aqueous systems was investigated by adsorption method using activated carbon obtained from the pumpkin seed waste. Activated carbon obtained from pumpkin seed waste functionalized with ZnCl2 was used as an absorbent. Pumpkin seed hydrochar was characterized by FT-IR, SEM, TGA-DTA, BET, and XPS. In the experimental stages, the adsorption equilibrium time was determined as 45 minutes, the adsorbent dosage was 0.8 g and the optimum pH was 6.0. After this step, the adsorption parameters of Langmuir, Freundlich, Temkin, and Dubinin-Radushkevich isotherms were investigated. It has been pointed out that the adsorption process fits better with the Freundlich isotherm model, and the adhesion occurs in a multilayered manner and on a heterogeneous surface. Freundlich and Dubinin-Radushkevich isotherms support that the bonding mechanism is realized by physical interactions. When the kinetic data were evaluated, it was found to be compatible with the pseudo-second-order kinetic model. The thermodynamic parameters of adsorption indicate that the system is endothermic, and the adsorption of Reactive Blue 19 on activated carbon is a spontaneous process.

Name probably for Plantago coronopus L.; in reference to the shape of basal leaves [1]. Plantago coronopus, commonly known as buckshorn banana (“diabelha” in Portugal), is a medical halophyte belonging to the Plantago L., the largest of the Plantaginaceae family [2]. Plantago will be those the vast majority paramount variety of the Plantaginaceae crew, What's more, will be utilized within customary prescription around the reality for separate purposes. Plantago coronopus L., Plantago major L., Plantago media L. also Plantago lanceolata L. would a large portion regularly utilized species of Plantago for a customary solution to turkey [3]. There would 28 taxa of the class Plantago did turkey and two of them are endemic [4]. In this study, extracts of Plantago coronopus L. subsp. the coronopus taxon was prepared with methanol (%80) solvent. Total phenolic contents were assessed by Folin Ciocalteau's method and were found as 32.66 mg gallic _acid /mL extract. The antioxidant activity was determined by using DPPH methods as 87.26%. And also, the chemical composition of the phenolic compounds was determined with LC-MS/MS instrument. As a result, 12 phenolic compounds were quantitatively detect, among the 27 phenolic compounds analyzed. These; Quinic acid (618±29.66 mg g ^-1 ), Malic acid (809.88±42.92 mgg ^-1 ), tr-Aconitic acid (4.49±0.22 mgg ^-1 ), Gallic acid (2.73±0.14 mgg ^-1 ), Protocatechuic acid (24.11±1.73 mgg ^-1 ), Tannic acid (33.01±1.68 mg g ^-l ), tr-Coffeic acid (11.06±0.58 mg g ^-l ), Vanilin (9.18±0.45 mgg ^-1 ), p-Coumaric acid (61.16±3.12 mgg ^-1 ), Kaempferol (43.64±2.27 mgg ^-1 ), Luteolin (5.35±0.37 mgg ^-1 ) and Apigenin (8.27±0.44 mgg ^-1 ).