Effective generalization in a multiple-category situation involves both assessing potential membership in individual categories and resolving conflict between categories while implementing a decision bound. We separated generalization from decision bound implementation using an information integration task in which category exemplars varied over two incommensurable feature dimensions. Human subjects first learned to categorize stimuli within limited training regions, and then, during fMRI scanning, they also categorized transfer stimuli from new regions of perceptual space. Transfer stimuli differed both in distance from the training region prototype and distance from the decision bound, allowing us to independently assess neural systems sensitive to each. Across all stimulus regions, categorization was associated with activity in the extrastriate visual cortex, basal ganglia, and the bilateral intraparietal sulcus. Categorizing stimuli near the decision bound was associated with recruitment of the frontoinsular cortex and medial frontal cortex, regions often associated with conflict and which commonly coactivate within the salience network. Generalization was measured in terms of greater distance from the decision bound and greater distance from the category prototype (average training region stimulus). Distance from the decision bound was associated with activity in the superior parietal lobe, lingual gyri, and anterior hippocampus, whereas distance from the prototype was associated with left intraparietal sulcus activity. The results are interpreted as supporting the existence of different uncertainty resolution mechanisms for uncertainty about category membership (representational uncertainty) and uncertainty about decision bound (decisional uncertainty).

Categorization involves organizing perceptual information so as to maximize differences along dimensions that predict class membership while minimizing differences along dimensions that do not. In the current experiment, we investigated how neural representations reflecting learned category structure vary according to generalization demands. We asked male and female human participants to switch between two rules when determining whether stimuli should be considered members of a single known category. When categorizing according to the “strict” rule, participants were required to limit generalization to make fine-grained distinctions between stimuli and the category prototype. When categorizing according to the “lax” rule, participants were required to generalize category knowledge to highly atypical category members. As expected, frontoparietal regions were primarily sensitive to decisional demands (i.e., the distance of each stimulus from the active category boundary), whereas occipitotemporal representations were primarily sensitive to stimulus typicality (i.e., the similarity between each exemplar and the category prototype). Interestingly, occipitotemporal representations of stimulus typicality differed between rules. While decoding models were able to predict unseen data when trained and tested on the same rule, they were unable to do so when trained and tested on different rules. We additionally found that the discriminability of the multivariate signal negatively covaried with distance from the active category boundary. Thus, whereas many accounts of occipitotemporal cortex emphasize its important role in transforming visual information to accentuate learned category structure, our results highlight the flexible nature of these representations with regards to transient decisional demands. SIGNIFICANCE STATEMENT Occipitotemporal representations are known to reflect category structure and are often assumed to be largely invariant with regards to transient decisional demands. We found that representations of equivalent stimuli differed between strict and lax generalization rules, and that the discriminability of these representations increased as distance from abstract category boundaries decreased. Our results therefore indicate that occipitotemporal representations are flexibly modulated by abstract decisional factors.

How do the neural representations underlying category learning change as skill develops? We examined perceptual category learning using a prototype learning task known to recruit a corticostriatal system including the posterior striatum, motor cortex, visual cortex, and intraparietal sulcus (IPS). Male and female human participants practiced categorizing stimuli as category members or nonmembers (A vs not-A) across 3 d, with fMRI data collected at the beginning and end. Univariate analyses found that corticostriatal activity in regions associated with habitual instrumental learning was recruited across both sessions, but activity in regions associated with goal-directed instrumental learning decreased from Day 1 to Day 3. Multivoxel pattern analysis (MVPA) indicated that after training, the trained category could be more easily decoded from the IPS when compared with a novel category. Representational similarity analysis (RSA) showed development of category representations in the IPS and motor cortex. In addition, RSA revealed evidence for category-related representations including prototype representation in the ventromedial prefrontal cortex which may reflect parallel development of schematic memory for the category structure. Overall, the results converge to show how performance of category decisions and representations of the category structure emerge after extensive training across the corticostriatal system underlying perceptual category learning.