Aim: This systematic review and meta-analysis aimed to evaluate the success rates of pulpotomy treatment for irreversible pulpitis in primary teeth. Methods: This study was registered and conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols. Relevant studies published between January 1980 and April 2023 were identified across eight online databases and two paediatric dentistry textbooks. Study selection, data extraction, and quality assessment were conducted by multiple investigators independently. Data analysis involved single-arm and two-arm meta-analyses, leave-one-out sensitivity analysis, meta-regression, and assessment of publication bias. The risks of bias were evaluated using the Cochrane Collaboration’s assessment tools. The levels of evidence were determined using the Oxford Centre for Evidence-Based Medicine (OCEBM) tool. Results: Five primary studies were included. The weighted mean overall success rates at 6-month and 12-month follow-ups were 97.2% and 94.4%, respectively. Two-arm meta-analysis revealed no significant difference (p > 0.05) between the use of mineral trioxide aggregate (MTA) and non-MTA bioceramic-based materials as pulpotomy medicaments. The sample size of each study did not affect the degree of data heterogeneity. Egger’s test revealed no significant publication bias. Conclusions: Pulpotomy may be regarded as an alternative modality for treating primary teeth with irreversible pulpitis. Nevertheless, future well-designed trials and extended follow-up periods are warranted.

Introduction: Children and adolescents with non-syndromic cleft lip and palate (CLP) experience a higher prevalence of caries and periodontal disease compared to those without CLP. This increased prevalence is often attributed to greater plaque accumulation, which can lead to gingival inflammation and periodontal disease. This study aims to analyze the correlation between oral health knowledge and awareness and the periodontal health status of orthodontic patients with cleft lip and palate (CLP).Method: This study used a cross-sectional approach. The study population consisted of orthodontic patients with non-syndromic CLP who met the inclusion criteria. The research was conducted at the UNPAD Dental Teaching Hospital (RSGM Unpad) from March to May 2024. Twenty-seven participants with non-syndromic CLP were included in the study. A non-probability, purposive sampling technique was employed. oral health knowledge and awareness were assessed using questionnaires, while periodontal health examinations were evaluated using the Community Periodontal Index (CPI). Correlation analyses were performed using Kendall's Concordance Correlation (W). Additionally, Spearman Rank Correlation Analysis was conducted to identify the dominant variables. Results: The analysis revealed a Kendall's Concordance Correlation (W) of 0.544, which is statistically significant (p < 0.0001), indicating a 54.4% relationship between the variables. The correlation between knowledge and periodontal health status in orthodontic patients with non-syndromic CLP was 11.16%, with a p-value of 0.0443 (p < 0.05) and an r-value of 0.33. The correlation between awareness of oral health and periodontal health status in these patients was 19.85%, with a p-value of 0.0099 (p<0.05) and an r-value of 0.45. Conclusion: There is a weak correlation between knowledge and awareness of oral health and the periodontal health status in non-syndromic CLP patients undergoing fixed orthodontic treatment.