In this study, the estimation of high-tech exports for Turkey’s foreign trade target in line with sustainable development was carried out. The research was carried out for Turkey since it has been focusing on sustainable and environmentally friendly production and an export-oriented growth model, with a transformation in its economic growth strategy as of 2021, and high-tech products are a determining factor in the export target. In this research, three different machine learning techniques, namely artificial neural networks, logistic regression, and support vector regression, were used to determine a successful prediction method close to the ideal scenario. In the models, high technology exports for the period of 2007–2023 with data obtained from the World Bank were taken as the dependent variable, while the gross national product, number of patents, and research and development expenditures were taken as independent variables. By calculating the R², MAPE, and MSE metrics, the success of the model with the least error was evaluated, and it was seen that artificial neural networks (ANNs) were the most successful model, with values of 94.2%, 0.011, and 0.073, respectively. The ANN model was followed by support regression and logistic regression.