Daniel Aparicio-López

Dr. Daniel Aparicio-López

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 December 2022 in Cirugía Española
Verified
Journal Article
Closed access
DADaniel Aparicio-López
Daniel Aparicio-López
LLLourdes Lahuerta-Lorente
Lourdes Lahuerta-Lorente
MGMaría Carmen García-Mur
María Carmen García-Mur
RIReyes Ibáñez-Carreras
Reyes Ibáñez-Carreras
CCCarmen Casamayor-Franco
Carmen Casamayor-Franco

2 October 2023 in Frontiers in Surgery
Verified
Journal Article
Open access
DADaniel Aparicio-López
Daniel Aparicio-López
JAJosé Manuel Asencio-Pascual
José Manuel Asencio-Pascual
GBGerardo Blanco-Fernández
Gerardo Blanco-Fernández
ECEsteban Cugat-Andorrá
Esteban Cugat-Andorrá
MGMiguel Ángel Gómez-Bravo
Miguel Ángel Gómez-Bravo
MSMario Serradilla-Martín
Mario Serradilla-Martín
Background: Surgical hemostasis has become one of the key principles in the advancement of surgery. Hemostatic agents are commonly administered in many surgical specialties, although the lack of consensus on the definition of intraoperative bleeding or of a standardized system for its classification means that often the most suitable agent is not selected. The recommendations of international organizations highlight the need for a bleeding severity scale, validated in clinical studies, that would allow the selection of the best hemostatic agent in each case. The primary objective of this study is to evaluate the VIBe scale (Validated Intraoperative Bleeding Scale) in humans. Secondary objectives are to evaluate the scale's usefulness in liver surgery; to determine the relationship between the extent of bleeding and the hemostatic agent used; and to assess the relationship between the grade of bleeding and postoperative complications.Methods: Prospective multicenter observational study including 259 liver resections that meet the inclusion criteria: patients scheduled for liver surgery at one of 10 medium-high volume Spanish HPB centers using an open or minimally invasive approach (robotic/laparoscopic/hybrid), regardless of diagnosis, ASA score <4, age ≥18, and who provide signed informed consent during the study period (September 2023 until the required sample size has been recruited). The participating researchers will be responsible for collecting the data and for reporting them to the study coordinators.Discussion: This study will allow us to evaluate the VIBe scale for intraoperative bleeding in humans, with a view to its subsequent incorporation in daily clinical practice.Clinical Trial Registration: https://clinicaltrials.gov/ct2/show/NCT05369988?term = serradilla&draw = 2&rank = 3, [NCT0536998].

24 February 2023 in Cirugía Española
Verified
Journal Article
Closed access
DADaniel Aparicio-López
Daniel Aparicio-López
RPRafael Cerdán Pascual
Rafael Cerdán Pascual
SBSonia Cantín Blázquez
Sonia Cantín Blázquez
LPLuis Antonio Ligorred Padilla
Luis Antonio Ligorred Padilla

29 November 2023 in Cirugía Andaluza
Verified
Journal Article
Closed access
DADaniel Aparicio-López
Daniel Aparicio-López
HMHk Kälviäinen Mejía
Hk Kälviäinen Mejía
CRC Gracia Roche
C Gracia Roche
MMMv Duque Mallén
Mv Duque Mallén
ASAC es la Asociación Andaluza de Cirujanos

24 April 2024 in Gastroenterology Insights
Verified
Journal Article
Open access
PDF file
GBGerardo Blanco
Gerardo Blanco
DADaniel Aparicio-López
Daniel Aparicio-López
CVCelia Villodre
Celia Villodre
IJIsabel Jaen-Torrejimeno
Isabel Jaen-Torrejimeno
CLCándido F Alcázar López
Cándido F Alcázar López
José Manuel RamiaJosé Manuel Ramia
José Manuel Ramia
We present a multicenter retrospective study of patients undergoing surgery for duodenal adenocarcinoma, from January 2010 to August 2020, in order to determine the epidemiological characteristics and the oncological results after surgical resection obtained in this rare tumor. Variables: demographics; tumor location; surgical intervention and immediate postoperative period; and post-surgical follow-up information, such as recurrence, overall survival (OS), and disease-free survival (DFS). A total of 32 patients underwent surgery. The median age was 69.74 years (IQR 60.47–79.09) and the male/female distribution was 3:1. The surgeries performed were: pancreaticoduodenectomy (PD) in 16 (50%) patients, segmental resection in 13 (40.6%), and the local excision of the lesion in three (9.4%). The R0 rate was higher in PD (86.7% vs. 42.9%; p = 0.013). The OS and DFS rate at one, three and five years was 95%, 70%, and 60% and 86%, 55%, and 48%, respectively. There was a greater trend towards recurrence in patients who did not undergo PD (53.8% vs. 25%; p = 0.14) and conservative surgery seemed to be associated with more local recurrence than PD (57.1% vs. 33.3%; p = 0.49). PD and limited resection are both valid options in the cases of non-ampullary duodenal adenocarcinoma, although PD presented lower rates of loco-regional recurrence.

25 August 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
DADaniel Aparicio-López
Daniel Aparicio-López
José Manuel RamiaJosé Manuel Ramia
José Manuel Ramia
CVCelia Villodre
Celia Villodre
JRJ.J Rubio-García
J.J Rubio-García
BRBelén Hernandez Roca
Belén Hernandez Roca
Mario Serradilla-MartínMario Serradilla-Martín
Mario Serradilla-Martín
Background/Objectives: Like many other countries, the management of pancreatic cancer in Spain has developed in a fragmented manner. This study analyzes clinical outcomes related to patient volume at different centers after left pancreatectomy (LP). Our goal is to determine whether our practices align with the standards established in the literature and assess whether centralization’s advantages significantly outweigh its disadvantages. Methods: The SPANDISPAN Project (SPANish DIStal PANcreatectomy) is an observational, prospective, multicenter study focused on LP conducted in Spanish Hepato-Pancreato-Biliary (HPB) Surgery Units from 1 February 2022 to 31 January 2023. HPB units were defined as high volume if they performed more than 10 LPs annually. Results: This study included 313 patients who underwent LP at 42 centers across Spain over the course of a year. A total of 40.3% of the procedures were performed in high-volume centers. Significant differences in preoperative variables were only observed in ASA scores, which were higher in the high-volume group. Intraoperatively, minimally invasive surgical techniques were performed more frequently in high-volume centers. Postoperatively, the administration of somatostatin, major complications, and B and C postoperative pancreatic fistula (POPF) were more frequent in low-volume hospitals. Conclusions: The findings revealed that high-volume centers had a higher rate of minimally invasive surgery, lower intraoperative bleeding, fewer complications, and reduced POPFs compared to low-volume centers. However, it is important to note that low-volume centers still demonstrated acceptable outcomes. Thus, the selective referral of more complex laparoscopic procedures could initiate a gradual centralization of surgical practices.