Jens Hooge

Mr. Jens Hooge

orcid

Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 July 2024 in Diagnostics
Verified
Journal Article
Open access
PDF file
POPedro Osorio
Pedro Osorio
GJGuillermo Jimenez-Perez
Guillermo Jimenez-Perez
JMJavier Montalt-Tordera
Javier Montalt-Tordera
JHJens Hooge
Jens Hooge
GDGuillem Duran-Ballester
Guillem Duran-Ballester
SMSadegh Mohammadi
Sadegh Mohammadi
Artificial Intelligence (AI)-based image analysis has immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially powerful solution is to augment training data with synthetic data. Latent diffusion models, which can generate high-quality, diverse synthetic images, are promising. However, the most common implementations rely on detailed textual descriptions, which are not generally available in this domain. This work proposes a method that constructs structured textual prompts from automatically extracted image features. We experiment with the PCam dataset, composed of tissue patches only loosely annotated as healthy or cancerous. We show that including image-derived features in the prompt, as opposed to only healthy and cancerous labels, improves the Fréchet Inception Distance (FID) by 88.6. We also show that pathologists find it challenging to detect synthetic images, with a median sensitivity/specificity of 0.55/0.55. Finally, we show that synthetic data effectively train AI models.

17 July 2025
Verified
Book Chapter
Closed access
PDF file
GJGuillermo Jimenez-Perez
Guillermo Jimenez-Perez
POPedro Osorio
Pedro Osorio
JCJosef Cersovsky
Josef Cersovsky
JMJavier Montalt-Tordera
Javier Montalt-Tordera
JHJens Hooge
Jens Hooge
SMSadegh Mohammadi
Sadegh Mohammadi