The piRNA pathway is essential for female fertility in golden hamsters and likely humans, but not in mice. However, the role of individual PIWIs in mammalian reproduction remains poorly understood outside of mice. Here, we describe the expression profiles, subcellular localization, and knockout-associated reproductive defects for all four PIWIs in golden hamsters. In female golden hamsters, PIWIL1 and PIWIL3 are highly expressed throughout oogenesis and early embryogenesis, while knockout of PIWIL1 leads to sterility, and PIWIL3 deficiency results in subfertility with lagging zygotic development. PIWIL1 can partially compensate for TE silencing in PIWIL3 knockout females, but not vice versa. PIWIL1 and PIWIL4 are the predominant PIWIs expressed in adult and postnatal testes, respectively, while PIWIL2 is present at both stages. Loss of any PIWI expressed in testes leads to sterility and severe but distinct spermatogenesis disorders. These findings illustrate the non-redundant regulatory functions of PIWI-piRNAs in gametogenesis and early embryogenesis in golden hamsters, facilitating study of their role in human fertility.

General relativity establishes the equality between matter-energy density and the Riemann curvature of spacetime. Therefore, light or matter will be bent or trapped when passing near the massive celestial objects, and Newton’s second law fails to explain it. The gravitational effect is not only extensively studied in astronomy but also attracts a great deal of interest in the field of optics. People have mimicked black holes, Einstein’s ring, and other fascinating effects in diverse optical systems. Here, with a gradient index lens, in the geometrical optics regime, we mimic the Schwarzschild precession in the orbit of the star S2 near the Galactic Center massive black hole, which was recently first detected by European Southern Observatory. We also find other series of gradient index lenses that can be used to mimic the possible Reissner–Nordström metric of Einstein’s field equation and dark matter particle motion. Light rays in such gradient lenses will be closed in some cases, while in other cases it would be trapped by the center or keep dancing around the center. Our work presents an efficient toy model to help investigate some complex celestial behaviors, which may require long period detection by using high-precision astronomical tools. The induced gradient lenses enlightened by the gravitational effect also enrich the family of absolute optical instruments for their selective closed trajectories.

In this work, we proposed a black phosphorus (BP) achiral metasurface and theoretically study the chiroptical response arising from extrinsic 2D-chirality in the mid-infrared regime. The achiral metasurface is composed of a monolayer BP sheet sandwiched by a silver ring array and dielectric spacer stacking on a silver substrate. The giant circular conversion dichroism (CCD) of the achiral metasurface is allowed at oblique incidence for the cooperative interaction of BP anisotropic surface plasmon modes and localized surface plasmons in metal rings, and the integrated BP can dynamically modulate the chiroptical response by controlling the doping concentration of BP. Furthermore, we found that a multiband phenomenon for CCD response occurs when tuning the thickness of the spacer. The proposed hybrid achiral metasurface provides more flexible opportunities to realize active polarization modulator, biosensor and chiral detection.

In this paper, we make an analogy of the interior Schwarzschild metric from transformation optics (we call the method transformation cosmology). It is shown that a simple refractive index profile is sufficient to capture the behavior of the metric to bend light. There is a critical value of the ratio of the radius of the massive star to the Schwarzschild radius, which is exactly related to the condition of collapsing into a black hole. We demonstrate the light bending effect for three cases from numerical simulations as well. Especially, we find that a point source at the photon sphere will form an image inside the star approximately, and the equivalent lens is like Maxwell’s fish-eye lens. This work will help us to explore the phenomena of massive stars with laboratory optical tools.

Super-focusing light using metamaterials and metasurfaces is of paramount importance in several applications, from integrated optics to microwave engineering and sensing. However, there are still some difficulties to realize broadband achromatic aberration highly efficient super-focusing from the far field to far field or quasi far field. In this Letter, based on conformal transformation optics, we propose a generalized conformal Luneburg lens (GCLL), which provides a new, to the best of our knowledge, strategy for quasi-far-field super-focusing with broadband (0.9–1.3 THz) achromatic aberration and high efficiency (above 60%). A relatively high numerical aperture (NA of 0.63) and sub-diffraction-limited resolution (FWHM of 0.45λ) are also obtained. The sample of the GCLL was designed using gradient metamaterials. The numerical simulation results verify that the focusing effects of the designed samples are consistent with the performance of the ideal GCLL.

We demonstrate an isotropic device called 540-degree deflecting lens, which has symmetric refractive index and can deflect parallel beam by 540 degrees. The expression of its gradient refractive index is obtained and generalized. We discover it’s an optical absolute instrument with self-imaging characteristic. Using conformal mapping, we deduce its general version in one-dimensional space. We also introduce a combined lens called the generalized inside-out 540-degree deflecting lens similar to the inside-out Eaton lens. Ray tracing and wave simulations are used to demonstrate their characteristics. Our study expands the family of absolute instruments and provides new ideas to design optical systems.