Sean Maudsley-Barton

Dr. Sean Maudsley-Barton

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Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 February 2020 in PLOS ONE
Verified
Journal Article
Open access
PDF file
SMSean Maudsley-Barton
Sean Maudsley-Barton
MYMoi Hoon Yap
Moi Hoon Yap
ABAnthony Bukowski
Anthony Bukowski
RMRichard Mills
Richard Mills
JMJamie McPhee
Jamie McPhee
Posturography provides quantitative, objective measurements of human balance and postural control for research and clinical use. However, it usually requires access to specialist equipment to measure ground reaction forces, which are not widely available in practice, due to their size or cost. In this study, we propose an alternative approach to posturography. It uses the skeletal output of an inexpensive Kinect depth camera to localise the Centre of Mass (CoM) of an upright individual. We demonstrate a pipeline which is able to measure postural sway directly from CoM trajectories, obtained from tracking the relative position of three key joints. In addition, we present the results of a pilot study that compares this method of measuring postural sway to the output of a NeuroCom SMART Balance Master. 15 healthy individuals (age: 42.3 ± 20.4 yrs, height: 172 ± 11 cm, weight: 75.1 ± 14.2 kg, male = 11), completed 25 Sensory Organisation Test (SOT) on a NeuroCom SMART Balance Master. Simultaneously, the sessions were recorded using custom software developed for this study (CoM path recorder). Postural sway was calculated from the output of both methods and the level of agreement determined, using Bland-Altman plots. Good agreement was found for eyes open tasks with a firm support, the agreement decreased as the SOT tasks became more challenging. The reasons for this discrepancy may lie in the different approaches that each method takes to calculate CoM. This discrepancy warrants further study with a larger cohort, including fall-prone individuals, cross-referenced with a marker-based system. However, this pilot study lays the foundation for the development of a portable device, which could be used to assess postural control, more cost-effectively than existing equipment.

16 July 2024 in Sensors
Verified
Journal Article
Open access
PDF file
SMSean Maudsley-Barton
Sean Maudsley-Barton
MYMoi Hoon Yap
Moi Hoon Yap
Falls are a major issue for those over the age of 65 years worldwide. Objective assessment of fall risk is rare in clinical practice. The most common methods of assessment are time-consuming observational tests (clinical tests). Computer-aided diagnosis could be a great help. A popular clinical test for fall risk is the five times sit-to-stand. The time taken to complete the test is the most commonly used metric to identify the most at-risk patients. However, tracking the movement of skeletal joints can provide much richer insights. We use markerless motion capture, allied with a representational model, to identify those at risk of falls. Our method uses an LSTM autoencoder to derive a distance measure. Using this measure, we introduce a new scoring system, allowing individuals with differing falls risks to be placed on a continuous scale. Evaluating our method on the KINECAL dataset, we achieved an accuracy of 0.84 in identifying those at elevated falls risk. In addition to identifying potential fallers, our method could find applications in rehabilitation. This aligns with the goals of the KINECAL Dataset. KINECAL contains the recordings of 90 individuals undertaking 11 movements used in clinical assessments. KINECAL is labelled to disambiguate age-related decline and falls risk.

1 October 2017
Verified
Conference Paper
Closed access
SMSean Maudsley-Barton
Sean Maudsley-Barton
JMJamie McPhee
Jamie McPhee
ABAnthony Bukowski
Anthony Bukowski
DLDaniel Leightley
Daniel Leightley
MYMoi Hoon Yap
Moi Hoon Yap
The analysis of human motion as a clinical tool can bring many benefits such as the early detection of disease and the monitoring of recovery, so in turn helping people to lead independent lives. However, it is currently under used. Developments in depth cameras, such as Kinect, have opened up the use of motion analysis in settings such as GP surgeries, care homes and private homes. To provide an insight into the use of Kinect in the healthcare domain, we present a review of the current state of the art. We then propose a method that can represent human motions from time-series data of arbitrary length, as a single vector. Finally, we demonstrate the utility of this method by extracting a set of clinically significant features and using them to detect the age related changes in the motions of a set of 54 individuals, with a high degree of certainty (F1-score between 0.9-1.0). Indicating its potential application in the detection of a range of age-related motion impairments.

10 September 2024
Verified
Conference Paper
Open access
MSMkululi Sikosana
Mkululi Sikosana
Oluwaseun AjaoOluwaseun Ajao
Oluwaseun Ajao
SMSean Maudsley-Barton
Sean Maudsley-Barton
This study evaluates the effectiveness of machine learning (ML) and deep learning (DL) models in detecting COVID-19-related misinformation on online social networks (OSNs), aiming to develop more effective tools for countering the spread of health misinformation during the pan-demic. The study trained and tested various ML classifiers (Naive Bayes, SVM, Random Forest, etc.), DL models (CNN, LSTM, hybrid CNN+LSTM), and pretrained language models (DistilBERT, RoBERTa) on the "COVID19-FNIR DATASET." These models were evaluated for accuracy, F1 score, recall, precision, and ROC, and used preprocessing techniques like stemming and lemmatization. The results showed SVM performed well, achieving a 94.41% F1-score. DL models with Word2Vec embeddings exceeded 98% in all performance metrics (accuracy, F1 score, recall, precision & ROC). The CNN+LSTM hybrid models also exceeded 98% across performance metrics, outperforming pretrained models like DistilBERT and RoBERTa. Our study concludes that DL and hybrid DL models are more effective than conventional ML algorithms for detecting COVID-19 misinformation on OSNs. The findings highlight the importance of advanced neural network approaches and large-scale pretraining in misinformation detection. Future research should optimize these models for various misinformation types and adapt to changing OSNs, aiding in combating health misinformation.

18 September 2023 in Scientific Data
Verified
Journal Article
Open access
PDF file
SMSean Maudsley-Barton
Sean Maudsley-Barton
MYMoi Hoon Yap
Moi Hoon Yap
The field of human action recognition has made great strides in recent years, much helped by the availability of a wide variety of datasets that use Kinect to record human movement. Conversely, progress towards the use of Kinect in clinical practice has been hampered by the lack of appropriate data. In particular, datasets that contain clinically significant movements and appropriate metadata. This paper proposes a dataset to address this issue, namely KINECAL. It contains the recordings of 90 individuals carrying out 11 movements, commonly used in the clinical assessment of balance. The dataset contains relevant metadata, including clinical labelling, falls history labelling and postural sway metrics. KINECAL should be of interest to researchers interested in the clinical use of motion capture and motion analysis.

22 May 2026 in Fluids and Barriers of the CNS
Verified
Journal Article
Open access
PDF file
RMRichard Mills
Richard Mills
TLTobias Langheinrich
Tobias Langheinrich
LULiis Uiga
Liis Uiga
KDKatherine A. J. Daniels
Katherine A. J. Daniels
SMSean Maudsley-Barton
Sean Maudsley-Barton
MTMats Tullberg
Mats Tullberg
Background: Idiopathic Normal Pressure Hydrocephalus (iNPH) is a leading cause of reversible gait disturbance in older adults, yet diagnosis and treatment selection remain limited by low-sensitivity clinical assessments. Conventional tests such as the 10-metre walk and Timed Up-and-Go capture overall performance but overlook the multidimensional, joint-level alterations that characterise iNPH gait. This study aimed to deliver the first comprehensive, three-dimensional (3D) biomechanical characterisation of iNPH gait to inform more objective diagnostic frameworks. Methods: Twenty-three participants with clinically diagnosed iNPH and eighteen age-matched healthy controls underwent baseline gait analysis (iNPH: pre tap test) consisting of overground walking using a 3D optoelectronic motion capture system with integrated force plates. Spatiotemporal parameters were compared using independent-samples t -tests, while continuous kinematic (i.e., joint angle) waveforms for the pelvis, hip, knee, and ankle were analysed using one-dimensional statistical parametric mapping (SPM). A binary logistic regression model was developed to classify participants as iNPH or healthy control. Results: Compared with controls, individuals with iNPH demonstrated markedly slower gait speed (–60%), shorter stride length (–52%), and greater stride width (+ 64%), each with large effect sizes (1.5–3.3; p < .001). SPM revealed multi-joint, phase-specific impairments in sagittal and frontal plane kinematics, including reduced pelvic obliquity, diminished hip flexion/extension and abduction, attenuated knee flexion during swing, and blunted ankle plantarflexion at push-off ( p < .05). These findings indicate impaired supraspinal coordination consistent with frontal-subcortical motor network dysfunction. Further, the statistical modelling achieved excellent discrimination between patients with iNPH and healthy controls. Due to short-stepped iNPH gait causing multiple consecutive steps on a single force plate, kinetics (i.e., ground reaction forces; joint moments) could not be analysed. Conclusions: This study suggests the first detailed biomechanical signatures of gait in iNPH, identifying spatiotemporal and joint-specific alterations that together define a central coordination deficit. Beyond confirming known gait slowing, these results delineate kinematic markers with translational potential as digital biomarkers for diagnosis and postoperative monitoring. By advancing gait analysis from simple bedside tests to detailed quantification, 3D motion capture offers a rigorous, reproducible framework that may improve diagnostic sensitivity in patients with iNPH. However, larger future studies should include clinically more heterogeneous cohorts and incorporate relevant disease mimics (e.g., Parkinson’s disease, progressive supranuclear palsy) to determine differentiation capabilities of the predictive modelling.