Background: Tissue engineering represents a promising field in regenerative medicine, with bioresorbable polymers such as polycaprolactone (PCL) playing a crucial role as scaffolds. These scaffolds support the growth and repair of tissues by mimicking the extracellular matrix. Objective: This study aimed to assess the in vivo performance of three-dimensional PCL scaffolds by evaluating their effects on bone repair in rat calvaria and the tissue reaction in subcutaneous implant sites, as well as their impact on major organs such as the kidneys, lungs, and liver. Methods: Three-dimensional scaffolds made of PCL were implanted in the subcutaneous tissue of rats’ backs and calvaria. Histological analyses were conducted to observe the bone repair process in calvaria and the tissue response in subcutaneous implant sites. Additionally, the kidneys, lungs, and livers of the animals were examined for any adverse tissue alterations. Results: The histological analysis of the bone repair in calvaria revealed newly formed bone growing towards the center of the defects. In subcutaneous tissues, a thin fibrous capsule with collagenous fibers enveloping the implant was observed in all animals, indicating a positive tissue response. Importantly, no harmful alterations or signs of inflammation, hyperplasia, metaplasia, dysplasia, or hemorrhage were detected in the kidneys, lungs, and liver. Conclusions: The findings demonstrate that PCL scaffolds produced through additive manufacturing are biocompatible, non-cytotoxic, and bioresorbable, promoting osteoconduction without adverse effects on major organs. Hence, PCL is confirmed as a suitable biomaterial for further studies in tissue engineering and regenerative medicine.

Dental replantation is the first treatment option after dental avulsion. However, avulsed teeth often develop root resorption or ankylosis after replantation caused by the absence of the vital periodontal ligament on the root surface and inadequate tooth storage for the first 60 minutes. Trauma patients may have associated a history of malocclusion requiring treatment. When dealing with young patients, one option is the decoronation technique, where the tooth is sectioned at the level of the neck (the crown is removed and the root is left in the sockets) with the aim of supporting the bone, avoiding bone grafting in the future for the placement of dental implants. Thus, this study aims to review the literature on the subject and report a clinical case involving dental avulsion and decoronation and orthodontic and prosthetic treatment. DOI:https://doi.org/10.56238/sevened2023.005-016

Introduction: Non-carious cervical lesions (NCCL) is a very common dental pathology frequently demanding resin composite restoration. Objective: This in vitro study had the objective to test the effect of altered dentin substrate by erosion and erosion/abrasion comparing it to sound dentin on the microtensile bond strength (µTBS) of All-Bond Universal (ABU) and Scotchbond Universal (SBU). Materials and methods: Seventy-two teeth were randomly divided in twelve experimental groups according to the adhesive system – ABU and SBU; approaching – self-etch (SE) and Etch-and-rinse (ER); and dentin condition – sound (S), eroded (E) and eroded/abraded (EA) dentin. The teeth/restorations were reduced to sticks and the µTBS was performed after 24 hours and 12 months of storage in water at 37°C. Results: Fractured specimens were analyzed under stereomicroscope to determine the failure patterns in adhesive/mixed or cohesive. µTBS data was analyzed through three-way ANOVA and Tukey’s test (α=5%). It was demonstrated that the adhesive system and the substrate influenced on the results (p=0.00), but aging did not (p=0.81). Regardless of time, SBU SE performed higher values of bond strength on E than the EA and S. Conclusion: EA dentin simulating NCCL did not impair the bond strength and presented similar behavior to sound dentin. DOI:https://doi.org/10.56238/sevened2023.005-018

The loss of the vertical occlusion dimension (OLD) is the result of a major occlusal imbalance, where, in addition to the loss of dental elements, the responsible factor may be parafunctions, such as bruxism. The reestablishment of the vertical dimension of occlusion is very important for the preparation of prosthetic works since its non-establishment can cause damage. The objective of this study was to conduct a narrative review of the literature to clarify the clinical repercussions caused by the alteration of the vertical dimension of occlusion. Studies on the subject were searched electronically through the Medline database, via PUBMED, without restricting the language of the publications and the limit of publication dates. The search strategy was developed using a combination of keywords and general terms related to the vertical dimension of occlusion and dental prosthesis. A total of 31 references were included in this review. According to the reviewed articles, we can infer that if the vertical dimension of occlusion is not correctly reestablished, remaining increased or decreased, damage may occur in the teeth, muscles, TMJ, swallowing, phonation, auditory system, and even in the patient's posture, affecting their balance, so its reestablishment is of paramount importance for the success of oral rehabilitation. DOI:https://doi.org/10.56238/sevened2023.005-020 A perda da dimensão vertical de oclusão (DVO) é resultado de um grande desequilíbrio oclusal, onde além da perda dos elementos dentários o fator responsável pode ser as parafunções, como o bruxismo. O restabelecimento da dimensão vertical de oclusão é muito importante para a confecção de trabalhos protéticos, pois o seu não reestabelecimento pode gerar danos. O objetivo deste estudo foi realizar uma revisão narrativa da literatura afim de esclarecer quais as repercussões clínicas causadas pela alteração da dimensão vertical de oclusão. Foram realizadas buscas de estudos sobre o tema eletronicamente através da base de dados Medline, via PUBMED, sem restringir o idioma das publicações e o limite de datas de publicação. A estratégia de busca foi elaborada utilizando uma combinação de palavras-chave e termos gerais relacionados à dimensão vertical de oclusão e prótese dentária. Nesta revisão foram incluídas 31 referências. De acordo com os artigos revisados podemos inferir que se a dimensão vertical de oclusão não for restabelecida corretamente, permanecendo aumentada ou diminuída, poderá ocorrer danos nos dentes, músculos, ATM, deglutição, fonação, sistema auditivo, e até mesmo na postura do paciente, acometendo o seu equilíbrio, portanto o seu restabelecimento é de suma importância para o sucesso das reabilitações orais. DOI:https://doi.org/10.56238/sevened2023.005-020

Tongue necrosis is a rare injury that often occurs, especially after trauma. This article reports the case of a 39-year-old patient who experienced partial tongue necrosis due to trauma. The patient underwent medical and prophylactic treatment with favorable results, avoiding the need for glossectomy. DOI: https://doi.org/10.56238/sevened2023.005-017

Background: The article addresses the impact of total temporomandibular joint replacement (TMJR) on oral health-related quality of life (OHRQoL) in patients with advanced temporomandibular joint (TMJ) disorder. TMJ disorder encompasses a variety of conditions causing pain and dysfunction in the jaw, peripheral nerves, and TMJ. TMJR is considered a last resort in the surgical treatment of advanced joint disorders when conservative treatments fail. Methods: The study followed 10 patients undergoing TMJR and assessed their oral health-related quality of life using the OHIP-14 (Oral Health Impact Profile-14) questionnaire at different postoperative time points. Results: The results showed a significant improvement in physical pain, psychological discomfort, and physical disability after six months, with a restoration of oral health-related quality of life after twelve months. Conclusions: The research concluded that TMJR treatment can significantly improve oral health-related quality of life in patients with advanced TMJ disorder. However, further studies are needed to analyze the long-term effectiveness of treatment and compare different surgical approaches.