Nazerke Zhanarystan

Dr. Nazerke Zhanarystan


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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7 August 2024 in Medicina
Verified
Journal Article
Open access
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AKAidos Konkayev
Aidos Konkayev
AKAssiya Kadralinova
Assiya Kadralinova
NZNazerke Zhanarystan
Nazerke Zhanarystan
NANurlan Akhatov
Nurlan Akhatov
AKAidos Konkayev
Aidos Konkayev
This article highlights a case of high-dose ferric carboxymaltose (Ferinject®) for the treatment of perioperative iron deficiency anaemia in a 39-year-old patient with dysplastic coxarthrosis. The patient was admitted routinely for a total hip replacement of the left hip joint. She had been suffering from pain, lameness, and restriction of movement in her left hip joint for the past several years. The patient was admitted with initial iron deficiency anaemia of a medium severity (Hgb—96.5 g/L, RBC—3.97 × 1012/L). Laboratory tests were taken to determine the iron deficiency, and transfusion readiness was submitted. The patient received ferric carboxymaltose infusion before surgery. The intraoperative blood loss was—100 mL with an operation duration of 50 min. On the first postoperative day, haemoglobin decreased to 86 g/L. No haemoglobin decrease was observed in the postoperative period, and 92 g/L was the amount of haemoglobin at the time of hospital discharge. The optimal dose for the treatment of perioperative anaemia has not been established; some studies recommend ferric carboxymaltose at a dose of 15 to 20 mg/kg and a maximum of 1000 mg once on the first day after surgery. The uniqueness of this case report is that a high dose of ferric carboxymaltose (1340 mg) during the preoperative period was applied. No side effects such as hypophosphatemia were reported. We believe that, in this clinical case, the patient managed to avoid large intraoperative blood loss and transfusions by using high doses of ferric carboxymaltose.

22 October 2025 in Frontiers in Medicine
Verified
Journal Article
Open access
PDF file
NZNazerke Zhanarystan
Nazerke Zhanarystan
SSShamil Shayakhanov
Shamil Shayakhanov
MKMaiya Konkayeva
Maiya Konkayeva
AKAssiya Kadralinova
Assiya Kadralinova
AKAidos Konkayev
Aidos Konkayev
This article presents a case of orthopedic treatment of a 51-year-old patient with latent iron deficiency anaemia and congenital dysplasia of both hip joints. The patient was admitted with complaints of severe pain and restriction of movement in the right hip joint, impaired joint function, shortening of the right lower limb, and lameness. A year prior, the patient had undergone surgery on the left hip joint to treat the same complaints. During the left hip surgery, the patient required haemotransfusion in the postoperative period to manage severe posthemorrhagic anaemia. In this clinical case, under equal conditions, the patient underwent preoperative preparation and administration of ferric carboxymaltose to compare the efficacy of iron deficiency correction versus no correction. No haemotransfusion was required in the postoperative period. The uniqueness of this clinical case is represented by the fact that the example of one patient showed the importance of preparation for orthopedic intervention and iron deficiency correction to avoid haemotransfusions, which are closely associated with infectious complications. In conclusion, preoperative correction of iron deficiency and treatment of latent anaemia in this clinical case was associated with no need for haemotransfusion in the postoperative period compared to no preoperative preparation. Further studies are needed.