Dr. Lei Zhang

1. Personal introduction Zhang Lei, Ph.D., associate professor, and master supervisor, Henan University, is mainly engaged in the screening and pharmacological research of anti-tumor and anti-fat accumulation small molecule drugs. 2. Representative Papers: (1) Zhang Lei, Liu Wen, Liu Fangyan, Wang Qun, Song Mengjiao, Yu Qi, Tang Kun, Teng Tieshan, Wu Dongdong, Wang Xijing, Han Wuqi, and Li Yanzhang. IMCA induces SLC7A11-mediated ferroptosis in colorectal cancer through AMPK/mTOR pathway. Oxidative Medicine and Cellular Lifespan, 2020. (2) Zhang Lei, Wang Qun, Liu Wen, Liu Fangyan, Ji Ailing*, and Li Yanzhang*. Orphan nuclear receptor 4a1: a potential new therapeutic target for metabolic diseases. Journal of Diabetes Research, 2018 (3) Zhang Lei, Liu Wen, Wang Qun, Li Qinpei, Wang Huijuan, Wang Jun, Teng Tieshan, Chen Mingliang, Ji Ailing*, and Li Yanzhang*. New candidate drugs targeting the 4A1 orphan nuclear receptor for the treatment of medullary thyroid carcinoma. Molecules, 2018, (4) Zhang Lei, Wang Feng, Jiang Zhenyou, Cen Yingzhou*, and Zhu Yaokui. Novel pentacyclic triterpenes from Humata tyermanni Moore have inhibitory activity on LPS-induced NO production in RAW264.7 macrophages. Chemical Electronic Journal, 2013, article number 727136: 1-4 (5) Hu Ying, Zhang Lei*, Wen Xiaoqiong, Zeng Xiaojun, Wen Rui, and Cen Yingzhou*. Two Diterpenoids from Nepeta splendens. Asian Journal of Natural Products, 2012, 14(8), 785-788