In this study, we demonstrate both theoretically and experimentally second harmonic generation (SHG) of a twisted vector vortex optical field (TVVOF) using a nonlinear type-II phase-matched β-BaB₂O₄ (BBO) crystal. Our study introduces a novel method to manipulate SHG by independently modulating the two orthogonal polarization components of a TVVOF. This flexibility in controlling SHG can be achieved through accurate experimental adjustments of the polarization components. Furthermore, we reveal that the SHG can be dynamically tuned by varying the angle between the polarization direction of the optical field and the principal axis of the BBO crystal via rotation. These findings provide a new approach for the flexible manipulation of SHG in structured vector optical fields, which have potential applications in optical communication, quantum optics, and photonic device engineering.