Miriam Kjörk Granström

Dr. Miriam Kjörk Granström


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2024 in Veterinary Sciences
Verified
Journal Article
Open access
PDF file
ABAnnika Bergström
Annika Bergström
MGMiriam Kjörk Granström
Miriam Kjörk Granström
LRLars Roepstorff
Lars Roepstorff
MAMohammad Jaber Alipour
Mohammad Jaber Alipour
KPKjerstin Pettersson
Kjerstin Pettersson
ILIngrid Ljungvall
Ingrid Ljungvall
(1) Background: The aim of the current pilot study was to describe the long-term effects of a single intra-articular injection of autologous stromal vascular fraction (SVF) with platelet-rich plasma (PRP) in dogs with confirmed elbow OA, using orthopedic lameness scoring and kinetic and kinematic gait analysis. For comparison of normal long-term variation of gait over time, a group of healthy control dogs (CDs) was also evaluated. (2) Methods: A prospective longitudinal clinical pilot study investigating 19 client-owned dogs with elbow OA (OADs) treated with SVF and PRP and eight CDs not receiving treatment. The OAD and CD groups were evaluated before and after 6 and at least 12 months following treatment with SVF and PRP (OAD group) and twice with a six-month interval (CD group), respectively, through orthopedic examinations, goniometry, and kinetic and kinematic analyses (seven variables). (3) Results: The OAD had an increase in fore–hind peak force symmetry ≥12 months after treatment (p < 0.05), but no other objective variables changed over time. Orthopedic consensus scores had improved at ≥six months follow-up evaluation (p < 0.05). None of the investigated gait variables had changed at ≥six months follow-up evaluation in the CD group. (4) Conclusions: The current study could not confirm a significant benefit from SVF and PRP treatment in OADs, but future studies should be conducted in order to fully evaluate the potential of the treatment. The improvement seen in fore–hindlimb symmetry may represent an improvement in gait or an incidental finding.

20 June 2024 in Acta Veterinaria Scandinavica
Verified
Journal Article
Open access
PDF file
MGMiriam Kjörk Granström
Miriam Kjörk Granström
LRLars Roepstorff
Lars Roepstorff
KPKjerstin Pettersson
Kjerstin Pettersson
ILIngrid Ljungvall
Ingrid Ljungvall
MDMaria Dimopoulou
Maria Dimopoulou
ABAnnika Bergström
Annika Bergström
Background: Kinetic and kinematic gait analysis is increasingly practised as a part of lameness evaluation in dogs. The aim of this study was to examine the normal short- and long-term variation in forelimb gait in sound control dogs (CD) at a walk using seven selected variables of objective kinetic and kinematic gait analyses. Also, to compare the findings in CD to a group of forelimb lame dogs with elbow osteoarthritis (OAD). An additional aim was to test a kinetic based graphic method for lameness detection; symmetry squares (SS). A prospective longitudinal study was carried out on client owned CD and OAD. Clinical and orthopaedic evaluations were performed to ensure soundness and detect and grade lameness. Seven kinetic and kinematic variables and SS were tested for lameness evaluation. The CD were divided into two subgroups, CD1 and CD2, and examined twice: CD1 with two months interval and CD2 with 3–4 h interval. The OAD group was evaluated once and compared to the CD groups’ first examination. Results: Thirteen CD and 19 OAD were included. For CD1 and CD2, there were no significant differences in any examined variable between examination occasions. Total peak force/impulse symmetry and fore-hind peak force/impulse symmetry differed significantly between OAD and CD. Symmetry squares had a 74% agreement to subjective orthopaedic evaluations. Conclusions: In CD, no difference in the examined variables was seen between examination occasions. Four out of seven objective variables differed significantly between CD and OAD. The graphic SS method might have diagnostic potential for lameness detection, making it possible to detect a shift from lame to non-lame limbs. Potentially, this might be especially helpful in bilaterally lame dogs, which often represent a clinical challenge in lameness evaluation.

9 January 2024 in Research Square
Verified
Preprint
Open access
PDF file
MGMiriam Kjörk Granström
Miriam Kjörk Granström
LRLars Roepstorff
Lars Roepstorff
KPKjerstin Pettersson
Kjerstin Pettersson
ILIngrid Ljungvall
Ingrid Ljungvall
MDMaria Dimopoulou
Maria Dimopoulou
ABAnnika Bergström
Annika Bergström
Background Kinetic and kinematic gait analysis is increasingly practised as a part of lameness evaluation in dogs. The aim of this study was to examine the normal short- and long-term variation in front limb gait in sound control dogs (CD) at a walk using seven selected variables of objective kinetic and kinematic gait analyses. Also, to compare the findings in CD to a group of front limb lame dogs with elbow osteoarthritis (OAD). An additional aim was to test a kinetic based graphic method for lameness detection; symmetry squares (SS). Study design: Prospective longitudinal study of client owned CD and OAD. Clinical and orthopaedic evaluations were performed to ensure soundness and detect and grade lameness. Seven kinetic and kinematic variables and SS were tested for lameness evaluation. The CD were divided into two subgroups, CD1 and CD2, and examined twice: CD1 with two months interval and CD2 with 3-4 hours interval. The OAD group was evaluated once and compared to the CD groups’ first examination. Results Thirteen CD and 19 OAD were included. For CD1 and CD2, there were no significant differences in any examined variable between examination occasions. Total peak force/impulse symmetry and fore-hind peak force/impulse symmetry differed significantly between OAD and CD. Symmetry squares had a 74% agreement to subjective orthopaedic evaluations. Conclusions: In CD, no difference in the examined variables was seen between examination occasions. Four out of seven objective variables differed significantly between CD and OAD. The graphic SS method might have diagnostic potential for lameness detection.

9 January 2024 in Research Square
Verified
Preprint
Open access
PDF file
ABAnnika Bergström
Annika Bergström
MGMiriam Kjörk Granström
Miriam Kjörk Granström
LRLars Roepstorff
Lars Roepstorff
MAMohammad Jaber Alipour
Mohammad Jaber Alipour
KPKjerstin Pettersson
Kjerstin Pettersson
ILIngrid Ljungvall
Ingrid Ljungvall
Background Autologous stromal vascular fraction (SVF) with platelet rich plasma (PRP) may be used to treat osteoarthritis (OA) in dogs, but there is a lack of evidence regarding long time follow up after treatment. The aim of the current study was to examine long-term effects of a single intra-articular injection of SVF and PRP in dogs with confirmed elbow OA using orthopaedic lameness scoring and kinetic and kinematic gait analysis. For comparison of normal long-term variation of gait over time, a group of healthy control dogs (CD) was also evaluated. Study design: Prospective longitudinal clinical study of 19 client owned dogs with elbow OA (OAD) treated with SVF and PRP and 8 CD not receiving treatment. Orthopaedic examinations, goniometry and seven kinetic and kinematic variables were evaluated before and six- and 12-months following treatment with SVF and PRP in the OAD group and twice with six months interval in the CD group. Orthopaedic examination variables (lameness, pain, range of motion) were scored and conflated to one out of three grades (normal, mildly or moderate/severely affected). Results: The OAD had an increase in fore-hind peak force symmetry 12 months after treatment (p< 0.05), but no other objective variables changed over time. Orthopaedic scores improved at six month follow up (p<0.05). None of the investigated gait variables had changed at six month follow up in the CD group. Conclusions: The current study did not show a clear benefit from SVF and PRP treatment in dogs with elbow OA.