Digital Twin (DT) technology in healthcare is relatively new and faces several challenges, e.g., real-time data processing, secure system integration, and robust cybersecurity. Despite the growing demand for real-time monitoring frameworks, further improvements remain possible. In this study, an architecture has been introduced that utilises cloud computing to create a DT ecosystem. A group of 20 participants has been monitored continuously using high-speed technology to track key physiological parameters, i.e., diabetes risk factors, heart rate (HR), oxygen saturation (SpO2) levels, and body temperature (BT). To strengthen the study and enhance diversity, the dataset was supplemented with 1177 anonymized medical records from the publicly available MIMIC-III Public Health Dataset. The DT model functions as a tool, storing both real-time sensor data and historical records, to effectively identify health risks and anomalies. An MLP model was combined with XGBoost, resulting in a 25% reduction in training time and a 33% reduction in testing time. The model demonstrated reliability with an accuracy of 98.9% and achieved real-time accuracy of 95.4%, alongside an F1 score of 0.984. Meticulous attention has been paid to cybersecurity measures, ensuring system integrity through end-to-end encryption and compliance with health data regulations. The incorporation of DT and AI within the healthcare sector is seen as having the potential to overcome existing limitations in monitoring systems, while workloads are relieved and data-driven diagnostics and decision-making processes are improved, e.g., through enhanced real-time patient monitoring and predictive analysis.

Task offloading frameworks play a crucial role in modern healthcare by optimizing resource utilization, reducing computational burdens, and enabling real-time medical decision-making. However, existing Digital Twin (DT)-based healthcare models suffer from high latency, inefficient resource allocation, cybersecurity vulnerabilities, and computational limitations when processing large-scale patient data. These constraints pose significant risks in time-sensitive applications such as ICU monitoring, robotic-assisted surgeries, and telemedicine. To address these limitations, this paper introduces a Quantum-Enhanced DT-IoT framework, integrating Artificial Intelligence (AI), Quantum Computing (QC), DT, and the Internet of Things (IoT) for real-time, secure, and efficient healthcare task offloading. The proposed system introduces two key optimization algorithms: (1) DTH-ATB-MAPPO, which dynamically adjusts task scheduling and resource distribution, and (2) AQDT-IoT, which enhances computational efficiency and cybersecurity compliance in 6 G-enabled IoT networks. By leveraging Approximate Amplitude Encoding (AAE) and Grover’s search, the framework enhances task offloading efficiency, enabling faster decision-making and optimized resource distribution across 6 G-enabled IoT networks. Empirical evaluations show that quantum preprocessing improved Task Offloading Success Rate (TOSR) by 32% and reduced the Error Rate (ER) by 80%, significantly outperforming traditional DT-based healthcare models. These enhancements enable. Additionally, theoretical analysis demonstrates computational speed enhancements, adaptive cybersecurity mechanisms, and improved system scalability, positioning this framework as a viable candidate for future cloud-based quantum healthcare infrastructures, even in resource-constrained hospital environments.

The development of Digital Twin (DT) systems for healthcare introduces new opportunities and challenges, particularly in the areas of real-time processing and predictive analytics. This research presents a hybrid cloud-edge architecture designed to improve the efficiency and responsiveness of remote healthcare monitoring. By integrating edge computing with cloud resources, the system facilitates real-time data transfer and decision-making based on live patient met-rics. A hybrid machine learning model, combining Multi-Layer Perceptron (MLP) and XGBoost, was applied to predict key health indicators, such as heart rate, blood oxygen saturation, body temperature, and diabetes mellitus. Far-edge and near-edge devices were deployed to handle data processing at various stages, reducing latency and improving overall system performance. The results demonstrate significant improvements, with a 40% reduction in latency, a 15% increase in efficiency, and 30% improvement in throughput compared to non-DT systems. The hybrid AI model exhibited robust performance, with cross-validation accuracy reaching 97.48% and real-time accuracy measured at 95.45%. Additionally, it reduced testing time by 58.4%, highlighting its efficiency for real-time healthcare applications. This framework enhances the scalability, efficiency, and reliability of remote healthcare systems, offering a practical solution for real-time patient monitoring in healthcare applications.

Digital Twin (DT) technology in healthcare is relatively new and faces several challenges, e.g., real-time data processing, secure system integration, and robust cybersecurity. Despite the growing demand for real-time monitoring frameworks, further improvements remain possible. In this study, an architecture has been introduced that utilises cloud computing to create a DT ecosystem. A group of 20 participants has been monitored continuously using high-speed technology to track key physiological parameters, i.e., diabetes risk factors, heart rate (HR), oxygen saturation (SpO2) levels, and body temperature (BT). The DT model functions as a tool, storing both real-time sensor data and historical records, to effectively identify health risks and anomalies. An MLP model was combined with XGBoost, resulting in a 25% reduction in training time and a 33% reduction in testing time. The model demonstrated reliability with an accuracy of 98.9% and achieved real-time accuracy of 95.4%, alongside an F1 score of 0.984. Meticulous attention has been paid to cybersecurity measures, ensuring system integrity through end-to-end encryption and compliance with health data regulations. The incorporation of DT and AI within the healthcare sector is seen as having the potential to overcome existing limitations in monitoring systems, while workloads are relieved and data-driven diagnostics and decision-making processes are improved, e.g., through enhanced real-time patient monitoring and predictive analysis