Negative emotions can adversely affect the treatment and recovery of breast cancer patients. Post-traumatic stress caused by cancer can increase the negative emotions of patients. This study assess...

Attentional bias to threatening information may play a vital role in the onset and maintenance of obsessive-compulsive disorder (OCD). This study aimed to explore whether adolescents with OCD exhibited attentional bias toward faces that express disgust or fear. Participants were 27 adolescents with a first-time primary diagnosis of OCD and 27 healthy controls. To assess OCD, depression, and anxiety symptoms, all participants completed the Yale–Brown Obsessive Compulsive Scale, the Hamilton Depression Scale, and the Hamilton Anxiety Scale, respectively, followed by the modified dot probe task. Repeated measures ANOVA revealed a main effect of validity type and a significant group × validity type interaction effect. The results of one sample t-tests showed that participants in the OCD group had an attentional bias toward both disgusted and fearful faces. Further analysis indicated that adolescents in the OCD group showed facilitated attention toward the fearful faces and difficulty disengaging from disgusted faces. Adolescents with OCD exhibited facilitated attention toward threat stimuli, and when they allocated attention to threat, they experienced difficulty disengaging from it. Treatment procedures to modify the attentional bias may be effective.

With the expansion of the ageing population, cognitive decline has become an increasingly pressing challenge. 1 As life expectancy increases, its socioeconomic burden is also increasing, highlighting the urgent need for effective interventions. Numerous studies suggest that specific dietary patterns and nutritional interventions may help mitigate cognitive decline associated with ageing.2 Among these, caloric restriction (CR), which aims to extend lifespan through reduced calorie intake, has gained significant research interest in recent years.3 However, the optimal CR regimen remains difficult to define due to the risk of malnutrition and other potential adverse effects. Moreover, maintaining long-term adherence to CR can be difficult for most individuals. Consequently, the use of caloric restriction mimetics (CRMs), compounds that replicate the physiological benefits of CR without requiring stringent dietary modifications, has emerged as a promising and potentially practical alternative. Among these, increasing evidence suggests that CR and intermittent fasting may elevate endogenous levels of spermidine (SPD), a polyamine compound now being investigated as a natural CRM candidate.4

This study examined the associations between posttraumatic stress symptoms (PTSS), anxiety, depression, and negative interpretation bias in breast cancer p