In this paper, a LabVIEW-based online monitoring and safety evaluation system for UAVs is designed to address the deficiencies in UAV flight state parameter monitoring and safety evaluation. The system consists of a lower unit for UAV recording and an upper unit on the ground. The lower unit collects and detects flight data and connects to the upper unit through a wireless digital transmission module via a serial port. The upper unit receives the data and carries out the monitoring and safety situation evaluation of the UAV. The lower unit of the system adopts multi-sensors to collect UAV navigation information in real time to achieve flight detection, while the upper unit adopts LabVIEW to design the UAV online monitoring and safety situation prediction system, enabling monitoring and safety situation prediction during UAV navigation. The test results show that the system can detect and comprehensively display the navigation information of the UAV in real time, and realize the safety evaluation and warning function of the UAV.