Dr. Chaim M. Roifman currently serves as Director of the Clinical Fellowship Training Program, the Division of Immunology and Allergy, and Director of the Immunology Service Laboratory, the Division of Immunology and Allergy, Canadian Centre for Primary Immunodeficiency, Hospital for Sick Children, Toronto, ON, Canada. Dr. Roifman has been a paediatrician and scientist at SickKids for over 35 years. He has made ground-breaking discoveries in understanding the molecular and genetic basis of inherited immune defects, including deficiencies in Zap70, CD25, CD3d, and Roifman syndrome. Dr. Roifman pioneered the use of matched unrelated transplants for patients without a suitable donor in the family and advanced therapies for patients affected by these life-threatening diseases. He continues to mentor the next generation of trainees with his bench-to-bedside approach to patient care. He is a member of the Order of Canada (2019) and was awarded the Exceptional Mentor Award by the Israeli Association of Allergy and Clinical Immunology (2018). Dr. Roifman’s translational research program focuses on unravelling the underlying causes of primary immunodeficiency.