Objectives: To assess in a prospective randomized trial two phycogenic bone substitutes—biphasic calcium phosphate (BCP) versus almost pure hydroxyapatite (HA)—for their volume stability and clinical implications after sinus floor elevation (SFE).Materials and Methods: Twenty patients requiring lateral‐window SFE 6 months prior to implant surgery were randomized to a BCP or HA group. As primary outcome, the grafts were analyzed for volume stability, using four cone‐beam computed tomography scans obtained immediately/6/12/24 months after SFE. Secondary outcomes were implant survivval, success, periotest values, oral‐health‐related quality of life (OHIP‐G14), and pain (VAS).Results: Kolmogorov–Smirnov goodness‐of‐fit test revealed normal distribution of samples (p = .200). At 6/12/24 months, the augmented volumes decreased to 96/92/90% (HA) or 99/96/96% (BCP). Volume changes were significantly a factor of time (p < .001; generalized linear model with repeated measures) and reached significantly lower values in HA group (p = .018). Significant intergroup difference in volume losses was notable at 24 months (p = .021; t‐test for independent samples). Periotest values decreased from −3/−4.1 (HA/BCP) after implant placement to −6.3/−4.5 (HA/BCP) after 6 months. OHIP scores diverged at 2 months (HA: 9.5; BCP: 5.2) and largely resolved by 24 months (HA: 1.3; BCP: 1.9). VAS scores were comparable, 2.2 at 1 week after SFE being their highest mean level.Conclusions: After 2 years, both groups experienced no biological or technical complications, demonstrating a consistent healing trajectory without notable symptoms. Although no significant differences were observed in implant stability and survival, BCP demonstrated higher volume stability than HA.

Background/Objectives: The long-term success of dental implants can be influenced by the material properties of abutments and their interaction with peri-implant tissues. This study investigates the impact of three abutment materials—titanium (Ti), zirconium oxide (Zr), and polymethylmethacrylate (PMMA)—on the inflammatory response in peri-implant sulcular fluid (PISF), using active-matrix metalloproteinase-8 (aMMP-8) as a biomarker. Methods: In this prospective, randomized clinical trial, 30 patients were assigned to Ti, Zr, or PMMA abutment groups. PISF samples were collected at predefined intervals over 12 months and analyzed for aMMP-8 levels using enzyme-linked immunosorbent assays (ELISA). Clinical parameters (probing depth, bleeding on probing, and plaque index) and radiographic assessments of bone resorption were also evaluated. Results: Two weeks after implant uncovering, baseline aMMP-8 levels varied significantly among materials, with Zr demonstrating the highest levels. Over time (2, 3, 6 and 12 months after implant uncovering), aMMP-8 levels decreased across all groups, with no significant differences observed at 12 months. Radiographic assessments indicated no statistically significant differences in bone resorption, with clinical parameters remaining comparable across all groups. Conclusions: Initial inflammatory responses to abutment materials may vary; however, all tested materials—Ti, Zr, and PMMA—showed long-term biocompatibility and supported healthy peri-implant tissue integration. These findings indicate that selecting any of the tested abutment materials does not significantly affect long-term peri-implant health.

Introduction: Dental implantology has seen rapid technological advancements, with artificial intelligence (AI) increasingly integrated into diagnostic, planning, and surgical processes. The release of chat‐generative pretrained transformer (ChatGPT) and its subsequent updates, including the deep research function, presents opportunities for AI‐assisted systematic reviews. However, its efficacy compared to traditional manual research has not been researched. Materials and Methods: A systematic review was conducted on May 6, 2025, to evaluate recent innovations in dental implantology and AI. Two parallel searches were performed: one using ChatGPT 4.1’s deep research tool in the PubMed database and another manual PubMed search by two independent reviewers. Both searches used identical keywords and Boolean operators targeting studies from 2020 to 2025. Inclusion criteria were peer‐reviewed studies related to implant design, osseointegration, guided placement, and other predefined outcomes. Results: The manual search identified 124 articles, of which 23 met the inclusion criteria. ChatGPT retrieved 114 articles, selected 13 for inclusion, yet only included 11 in its synthesis. Two cited articles by the AI software were nonexistent, and numerous relevant studies were not retrieved, whereas the remaining articles were correct and found by manual search as well. ChatGPT had high specificity (98%) and low sensitivity (47.8%), with a statistically significant difference compared to manual search and selection. Discussion: AI tools like ChatGPT show promise in literature search, synthesis, and assistance, especially in improving readability and identifying trending topics in science. Nevertheless, the current state of deep research function lacks the reliability required for conducting systematic reviews due to issues such as made‐up references and missed articles. The results highlight the need for human supervision and improved safeguards. Conclusions: ChatGPT’s deep research function can support, but not replace manual systematic search and selection. It offers substantial benefits in writing support and preliminary synthesis due to acceptable accuracy, but limitations in reliability and low sensitivity (47.8%) require cautious use and transparent reporting of any AI involvement in scientific research.

Objectives: This prospective observational study aimed to evaluate the clinical outcomes and impact of different treatment protocols - immediate loading using a round gold bar retained overdenture on two implants, submucosal healing, and transmucosal healing - on circumferential marginal bone levels around dental implants. Materials and methods: 20 patients requiring six implants in the edentulous lower jaw were included. Within each patient, 2 implants were assigned to submucosal healing, transmucosal healing, or immediate loading protocols. Marginal bone loss (MBL) was evaluated using 3D scanning at implant placement and after 4 months while raising a full-thickness flap. Periotest values (PTVs), the oral health impact profile (OHIP-14) and regular clinical evaluations were conducted for up to 2 years. Results: The submucosal group exhibited the least mean vertical MBL (-0.22 mm), significantly lower than the immediate (-0.39 mm) and transmucosal (-0.36 mm) groups (P = .001). Peri-implant bone surface area reduction was lowest in the submucosal group (-0.87 mm²) compared to the transmucosal (-4.58 mm²) and immediate (-6.66 mm²) protocols (P = .002). One submucosal healed implant and two immediately loaded implants were lost. Immediate loading provided high patient comfort and demonstrated successful outcomes both in terms of clinical data (PTVs, MBL) and patient-reported outcome measures (OHIP-14, VAS). Conclusions: Submucosal and transmucosal healing protocols resulted in better marginal bone preservation compared to immediate loading. Although immediate loading enhanced patient comfort, it was associated with higher marginal bone loss. Clinical relevance: This study highlights the potential advantages of submucosal healing for marginal bone preservation and supports the use of three-dimensional scanning for precise bone loss evaluation, guiding clinical decision-making in implantology. Trial registration: ClinicalTrials.gov Identifier: NCT06408506.

Background: Occupational factors and the type of instrument played may influence physical and psychological health, affecting oral health-related quality of life (OHRQoL). This study assessed the prevalence of orofacial pain, sleep bruxism, stress, and OHRQoL among woodwind musicians (oboe, flute, clarinet, bassoon) in German professional orchestras, compared to cellists. Methods: A standard online questionnaire was sent to all 129 German professional orchestras. Orofacial pain, stress, and sleep-related issues in the past 30 days were evaluated. The German version of the Oral Health Impact Profile-14 (OHIP-14) assessed OHRQoL. Logistic and linear regression analyses were performed (statistical significance p < 0.05). Results: A total of 243 musicians were included. Orofacial pain was reported by 35.8%, sleep bruxism by 63.0%, and stress by 88.9% of the participant. Orofacial pain was significantly associated with female gender (p = 0.027; odds ratio [OR] = 2.09, 95% confidence interval [CI]: 1.09–4.02), frequent sleep bruxism (p = 0.013; OR = 2.65, 95%-CI: 1.23–5.69), frequent stress (p = 0.002; OR = 3.19, 95%-CI: 1.53–6.63), and difficulties initiating sleep after evening shifts (p = 0.003; OR = 2.90, 95%-CI: 1.45–5.80), but not with the instrument played. OHIP-14 scores did not differ significantly between instrument groups (p = 0.629), but correlated with orofacial pain (p < 0.001), sleep bruxism (p < 0.001), stress (p = 0.002), and sleep difficulties (p = 0.040). Conclusions: Orofacial pain and sleep bruxism are common among professional musicians, with stress-related factors playing a more significant role than the instrument played. Trial registration: ClinicalTrials.gov, NCT06618898, 27.09.2024.