Students often find it difficult to understand phenomena of everyday life that occur in the natural world, such as the phenomenon of expansion and contraction of liquids, in which there are many misinterpretations. To address this difficulty, this paper suggests another perspective on the didactic approach based on Mixed Reality, the attunement of the two worlds, the virtual and the real, and examines its effectiveness in teaching the phenomenon of fluid expansion. The main pillar of the educational process is teachers and the practices they use in the teaching process. For this reason, the sample of this survey consisted of 54 University students and prospective elementary education teachers. The mixed research approach was followed to collect the data. Through a Mixed Reality environment, using HoloLens 2, students followed a well-structured scenario and worksheets and observations to investigate the phenomenon of expansion/contraction of different fluids. The results demonstrate that through the interaction and direct feedback of the Mixed Reality environment, students gained a deeper understanding of the phenomenon. At the same time, the device was characterized as a particularly useful educational tool that should be accessible to all students for a better familiarization with complex scientific data.