Louis Niessen

Dr. Louis Niessen

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Research Focus & Metrics

Academic Career Length

51Years (1976-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2006 in Cost Effectiveness and Resource Allocation
Verified
Journal Article
Open access
PDF file
RBRob Baltussen
Rob Baltussen
LNLouis Niessen
Louis Niessen
Priority setting of health interventions is often ad-hoc and resources are not used to an optimal extent. Underlying problem is that multiple criteria play a role and decisions are complex. Interventions may be chosen to maximize general population health, to reduce health inequalities of disadvantaged or vulnerable groups, ad/or to respond to life-threatening situations, all with respect to practical and budgetary constraints. This is the type of problem that policy makers are typically bad at solving rationally, unaided. They tend to use heuristic or intuitive approaches to simplify complexity, and in the process, important information is ignored. Next, policy makers may select interventions for only political motives.

1 March 2003 in The Lancet
Verified
Journal Article
Closed access
CMChristopher Jl Murray
Christopher Jl Murray
JLJeremy A Lauer
Jeremy A Lauer
RHRaymond Cw Hutubessy
Raymond Cw Hutubessy
LNLouis Niessen
Louis Niessen
NTNiels Tomijima
Niels Tomijima
DEDavid B Evans
David B Evans

1 March 2002 in Diabetes Care
Verified
Journal Article
Closed access
PDF file
WRW. Ken Redekop
W. Ken Redekop
MKMarc A. Koopmanschap
Marc A. Koopmanschap
RSRonald P. Stolk
Ronald P. Stolk
GRGuy E.H.M. Rutten
Guy E.H.M. Rutten
BWBruce H.R. Wolffenbuttel
Bruce H.R. Wolffenbuttel
LNLouis Niessen
Louis Niessen
OBJECTIVE— To estimate the health-related quality of life (HRQOL) and treatment satisfaction for patients with type 2 diabetes in the Netherlands and to examine which patient characteristics are associated with quality of life and treatment satisfaction. RESEARCH DESIGN AND METHODS—For a sample of 1,348 type 2 diabetes patients, recruited by 29 general practitioners, we collected data regarding HRQOL. This study was performed as part of a larger European study (Cost of Diabetes in Europe - Type 2 [CODE-2]). We used a generic instrument (Euroqol 5D) to measure HRQOL. Treatment satisfaction was assessed using the Diabetes Treatment Satisfaction Questionnaire. RESULTS—Patients without complications had an HRQOL (0.74) only slightly lower than similarly aged persons in the general population. Insulin therapy, obesity, and complications were associated with a lower HRQOL, independent of age and sex. Although higher fasting blood glucose and HbA1c levels were negatively associated with HRQOL, these factors were not significant after adjustment for other factors using multivariate analysis. Overall treatment satisfaction was very high. Younger patients, patients using insulin, and patients with higher HbA1c levels were less satisfied with the treatment than other patients. CONCLUSIONS—Obesity and the presence of complications are important determinants of HRQOL in patients with type 2 diabetes.

1 May 2018 in The Lancet
Verified
Journal Article
Open access
LNLouis Niessen
Louis Niessen
DMDiwakar Mohan
Diwakar Mohan
JAJonathan K Akuoku
Jonathan K Akuoku
AMAndrew J Mirelman
Andrew J Mirelman
SASayem Ahmed
Sayem Ahmed
DPDavid H Peters
David H Peters
Five Sustainable Development Goals (SDGs) set targets that relate to the reduction of health inequalities nationally and worldwide. These targets are poverty reduction, health and wellbeing for all, equitable education, gender equality, and reduction of inequalities within and between countries. The interaction between inequalities and health is complex: better economic and educational outcomes for households enhance health, low socioeconomic status leads to chronic ill health, and non-communicable diseases (NCDs) reduce income status of households. NCDs account for most causes of early death and disability worldwide, so it is alarming that strong scientific evidence suggests an increase in the clustering of non-communicable conditions with low socioeconomic status in low-income and middle-income countries since 2000, as previously seen in high-income settings. These conditions include tobacco use, obesity, hypertension, cancer, and diabetes. Strong evidence from 283 studies overwhelmingly supports a positive association between low-income, low socioeconomic status, or low educational status and NCDs. The associations have been differentiated by sex in only four studies. Health is a key driver in the SDGs, and reduction of health inequalities and NCDs should become key in the promotion of the overall SDG agenda. A sustained reduction of general inequalities in income status, education, and gender within and between countries would enhance worldwide equality in health. To end poverty through elimination of its causes, NCD programmes should be included in the development agenda. National programmes should mitigate social and health shocks to protect the poor from events that worsen their frail socioeconomic condition and health status. Programmes related to universal health coverage of NCDs should specifically target susceptible populations, such as elderly people, who are most at risk. Growing inequalities in access to resources for prevention and treatment need to be addressed through improved international regulations across jurisdictions that eliminate the legal and practical barriers in the implementation of non-communicable disease control.

1 May 2018 in The Lancet
Verified
Journal Article
Closed access
RNRachel Nugent
Rachel Nugent
MBMelanie Y Bertram
Melanie Y Bertram
SJStephen Jan
Stephen Jan
LNLouis Niessen
Louis Niessen
FSFranco Sassi
Franco Sassi
RBRobert Beaglehole
Robert Beaglehole

1 July 1976 in Neuroscience Letters
Verified
Journal Article
Closed access
DHDavid A. Hopkins
David A. Hopkins
LNLouis Niessen
Louis Niessen