Discharging of untreated municipal solid wastes (MSWs) onto land is very widespread in developing countries. The compounds contained in MSW cause a harmful effect to human and environment. Hence, an assessment of the extent of their local impact is of great interest to figure out the pollution they cause. Therefore, this study aimed at evaluating the effects of discharge of solid wastes on soil quality within the landfill of Ain-El-Hammam municipality (Algeria). To achieve this, different soil physicochemical parameters were considered: granulometry, electrical conductivity, pH, organic matter content, and heavy metal concentration. The results indicated the influence of the MSW on the physicochemical characteristics of the soil by enhancing the organic matter content of soil (4.53%) and increasing heavy metal content (Cu, Zn, Cd, Pb, Ni, and Cr), which is a clear indication of the level of pollution they are generating.

Mining of organophosphorous (OPs)-degrading bacterial enzymes in collections of known bacterial strains and in natural biotopes are important research fields that lead to the isolation of novel OP-degrading enzymes. Then, implementation of strategies and methods of protein engineering and nanobiotechnology allow large-scale production of enzymes, displaying improved catalytic properties for medical uses and protection of the environment. For medical applications, the enzyme formulations must be stable in the bloodstream and upon storage and not susceptible to induce iatrogenic effects. This, in particular, includes the nanoencapsulation of bioscavengers of bacterial origin. In the application field of bioremediation, these enzymes play a crucial role in environmental cleanup by initiating the degradation of OPs, such as pesticides, in contaminated environments. In microbial cell configuration, these enzymes can break down chemical bonds of OPs and usually convert them into less toxic metabolites through a biotransformation process or contribute to their complete mineralization. In their purified state, they exhibit higher pollutant degradation efficiencies and the ability to operate under different environmental conditions. Thus, this review provides a clear overview of the current knowledge about applications of OP-reacting enzymes. It presents research works focusing on the use of these enzymes in various bioremediation strategies to mitigate environmental pollution and in medicine as alternative therapeutic means against OP poisoning.