DNA is an intelligent data storage medium due to its stability and high density. It has been used by nature for over 3.5 billion years. Compared with traditional methods, DNA offers better compression and physical density. DNA can retain information for thousands of years. However, challenges exist in scalability, standardization, metadata gathering, biocybersecurity, and specialized tools. Addressing these challenges is crucial for widespread implementation. Collaboration among experts, as well as keeping the future in mind, is needed to unlock the full potential of DNA data storage, which promises low energy costs, high-density storage, and long-term stability.
3 August 2016 in International Journal of Chemistry
Emulsions are thermodynamically unstable systems where droplet size is one of the main factors that affect its physical stability and consequently their quality. In this context, this work analyses the incorporation of a high shear homogenization step in the manufacturing process of an emulsion with the objective of maintaining its physical stability. In order to demonstrate the effects of this homogenization in the manufacturing process, the emulsion characterization was carried out by microscopy, rheology, laser diffraction and analytical photo-centrifugation techniques. The effect of high shear homogenization into the emulsion physical results was dependent on the speed applied to the homogenizer pump, with an effective 3600 rpm speed. There was no evidence of change on pH attributes and emulsion density, although there was a change in volumetric relationship between the droplet family presented in each sample, reducing the population of larger droplets to form a third family of intermediate droplets and increasing the volumetric proportion of the population of smaller droplets. This profile change in the droplet size distribution contributed to increased viscosity and emulsion without the presence of separation after it was submitted to the stress condition of temperature and agitation.
1 April 2020 in European Journal of Pharmaceutical Sciences