Marina Garofano

Dr. Marina Garofano

orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 April 2020 in Monaldi Archives for Chest Disease
Verified
Journal Article
Open access
PDF file
MVMichele Vitacca
Michele Vitacca
MLMarta Lazzeri
Marta Lazzeri
EGenrico eugenio guffanti
enrico eugenio guffanti
PFPamela Frigerio
Pamela Frigerio
FDFrancesco D'Abrosca
Francesco D'Abrosca
SISifir
Sifir
There is a need of consensus about the pulmonary rehabilitation (PR) in patients with COVID-19 after discharge from acute care. To facilitate the knowledge of the evidence and its translation into practice, we developed suggestions based on experts’ opinion. A steering committee identified areas and questions sent to experts. Other international experts participated to a RAND Delphi method in reaching consensus and proposing further suggestions. Strong agreement in suggestions was defined when the mean agreement was >7 (1 = no agreement and 9 = maximal agreement). Panelists response rate was >95%. Twenty-three questions from 4 areas: Personnel protection equipment, phenotypes, assessments, interventions, were identified and experts answered with 121 suggestions, 119 of which received high level of concordance. The evidence-based suggestions provide the clinicians with current evidence and clinical experts opinion. This framework can be used to facilitate clinical decision making within the context of the individual patient. Further studies will evaluate the clinical usefulness of these suggestions.

21 March 2021 in Life
Verified
Journal Article
Open access
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MCMariaconsiglia Calabrese
Mariaconsiglia Calabrese
MGMarina Garofano
Marina Garofano
RPRoberta Palumbo
Roberta Palumbo
PPPaola Di Pietro
Paola Di Pietro
Carmine IzzoCarmine Izzo
Carmine Izzo
CVCarmine Vecchione
Carmine Vecchione
Recent scientific literature has investigated the cardiovascular implications of COVID-19. The mechanisms of cardiovascular damage seem to involve the protein angiotensin-converting enzyme 2 (ACE2), to which severe acute respiratory syndrome (SARS) coronavirus-2 (CoV-2) binds to penetrate cells and other mechanisms, most of which are still under study. Cardiovascular sequelae of COVID-19 include heart failure, cardiomyopathy, acute coronary syndrome, arrhythmias, and venous thromboembolism. This article aims to collect scientific evidence by exploiting PubMed, Scopus, and Pedro databases to highlight the cardiovascular complications of COVID-19 and to define the physiotherapy treatment recommended for these patients. Exercise training (ET), an important part of cardiac rehabilitation, is a powerful tool in physiotherapy, capable of inducing significant changes in the cardiovascular system and functional in the recovery of endothelial dysfunction and for the containment of thromboembolic complications. In conclusion, due to the wide variety of possible exercise programs that can be obtained by combining intensity, duration, and speed in various ways, and by adjusting the program based on continuous patient monitoring, exercise training is well suited to the treatment of post-COVID patients with an impaired cardiovascular system of various degrees.

6 May 2025 in Technologies
Verified
Journal Article
Open access
PDF file
MGMarina Garofano
Marina Garofano
RSRosaria Del Sorbo
Rosaria Del Sorbo
MCMariaconsiglia Calabrese
Mariaconsiglia Calabrese
MGMassimo Giordano
Massimo Giordano
MPMaria Pia Di Palo
Maria Pia Di Palo
BABramanti Alessia
Bramanti Alessia
Background: Chronic low back pain (CLBP) is a leading cause of disability, impacting quality of life (QoL), function, and work productivity. Traditional rehabilitation faces challenges in accessibility and adherence. Remote rehabilitation and virtual reality (VR) interventions using motion sensors offer real-time movement tracking, biofeedback, and personalized exercises. This systematic review evaluates their effectiveness in pain reduction, functional improvement, adherence, and QoL. Methods: A systematic search was performed across PubMed, Scopus, Web of Science, and PEDro (2015–2025), including randomized controlled trials, observational, and feasibility studies on adults with CLBP undergoing sensor-based digital rehabilitation. The primary outcomes included pain, functional mobility, and movement biomechanics; secondary outcomes included adherence, QoL, and cost-effectiveness. Eight studies involving 7166 participants were included. Overall, sensor-based remote rehabilitation and VR interventions demonstrated positive effects on pain, function, and adherence. Pain reductions ranged from modest short-term decreases to over 60% in long-term programs (e.g., −68.5% in VAS). Functional improvements included lumbar ROM gains up to +9.9° and better movement control. Adherence was consistently high, with some programs reporting completion rates between 73% and 90%, particularly those incorporating gamification or real-time feedback. Selected studies also showed QoL improvements (e.g., +9.10 points on SF-36) and reductions in work impairment by over 60%. A few trials reported significant decreases in inflammatory markers (e.g., CRP −1.16 mg/L, TNF-α −8.9 pg/mL). Conclusions: Motion sensor-based remote rehabilitation and VR interventions show promising results in pain management, mobility, and adherence for individuals with CLBP. Gamification and biofeedback features enhance engagement, addressing a key challenge of conventional rehabilitation. However, more long-term RCTs and economic evaluations are needed to confirm their effectiveness and cost-efficiency.

26 June 2024 in Healthcare
Verified
Journal Article
Open access
PDF file
MPMaria Pagano
Maria Pagano
FCFrancesco Corallo
Francesco Corallo
AAANNA ANSELMO
ANNA ANSELMO
FGFabio Mauro Giambò
Fabio Mauro Giambò
GMGiuseppe Micali
Giuseppe Micali
ICIrene Cappadona
Irene Cappadona
Heart failure (HF) is a growing epidemic, affecting millions of people worldwide, and is a major cause of mortality, morbidity, and impaired quality of life. Traditional cardiac rehabilitation is a valuable approach to the physical and quality-of-life recovery of patients with cardiovascular disease. The innovative approach of remote monitoring through telemedicine offers a solution based on modern technologies, enabling continuous collection of health data outside the hospital environment. Remote monitoring devices present challenges that could adversely affect patient adherence, resulting in the risk of dropout. By applying a cognitive-behavioral model, we aim to identify the antecedents of dropout behavior among patients adhering to traditional cardiac rehabilitation programs and remote monitoring in order to improve the latter. Our study was conducted from October 2023 to January 2024. In the first stage, we used data from literature consultation. Subsequently, data were collected from the direct experience of 49 health workers related to both remote monitoring and traditional treatment, recruited from the authors’ workplace. Results indicate that patients with cardiovascular disease tend to abandon remote monitoring programs more frequently than traditional cardiac rehabilitation therapies. It is critical to design approaches that take these barriers into account to improve adherence and patient satisfaction. This analysis identified specific antecedents to address, helping to improve current monitoring models. This is crucial to promote care continuity and to achieve self-management by patients in the future.

10 July 2024 in Healthcare
Verified
Journal Article
Open access
PDF file
GMGiuseppe Micali
Giuseppe Micali
FCFrancesco Corallo
Francesco Corallo
MPMaria Pagano
Maria Pagano
FGFabio Mauro Giambò
Fabio Mauro Giambò
ADAntonio Duca
Antonio Duca
ICIrene Cappadona
Irene Cappadona
Cardiovascular and neurological diseases are a major cause of mortality and morbidity worldwide. Such diseases require careful monitoring to effectively manage their progression. Artificial intelligence (AI) offers valuable tools for this purpose through its ability to analyse data and identify predictive patterns. This review evaluated the application of AI in cardiac and neurological diseases for their clinical impact on the general population. We reviewed studies on the application of AI in the neurological and cardiological fields. Our search was performed on the PubMed, Web of Science, Embase and Cochrane library databases. Of the initial 5862 studies, 23 studies met the inclusion criteria. The studies showed that the most commonly used algorithms in these clinical fields are Random Forest and Artificial Neural Network, followed by logistic regression and Support-Vector Machines. In addition, an ECG-AI algorithm based on convolutional neural networks has been developed and has been widely used in several studies for the detection of atrial fibrillation with good accuracy. AI has great potential to support physicians in interpretation, diagnosis, risk assessment and disease management.

2 August 2024 in Healthcare
Verified
Journal Article
Open access
PDF file
MGMarina Garofano
Marina Garofano
CVCarmine Vecchione
Carmine Vecchione
MCMariaconsiglia Calabrese
Mariaconsiglia Calabrese
MRMaria Rosaria Rusciano
Maria Rosaria Rusciano
Valeria ViscoValeria Visco
Valeria Visco
BABramanti Alessia
Bramanti Alessia
Background: Cardiovascular diseases (CVDs) are associated with very high rates of re-hospitalization and mortality worldwide, so the complexity of these pathologies requires frequent access to hospital facilities. The guidelines also emphasize the importance of cardiac rehabilitation (CR) programs, which have demonstrated a favorable effect on outcomes, and cardiac telerehabilitation (CTR) could represent an innovative healthcare delivery model. The aim of our review is to study how technologies used in rehabilitation have changed over time and also to understand what types of rehabilitation programs have been used in telerehabilitation. Methods: We searched randomized controlled trials (RCTs) in three electronic databases, PubMed, Web of Science, and Scopus, from January 2015 to January 2024, using relevant keywords. Initially, 502 articles were found, and 79 duplicates were identified and eliminated with EndNote. Results: In total, 16 RCTs fulfilled the pre-defined criteria, which were analyzed in our systematic review. The results showed that after CTR, there was a significant improvement in main outcome measures, as well as in relation to technological advances. Conclusions: Moreover, compared to center-based rehabilitation, CTR can offer further advantages, with better cost-effectiveness, the breakdown of geographical barriers, and the improvement of access to treatment for the female population, which is traditionally more socially committed.