Chin Long Poo

Mr. Chin Long Poo

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 December 2022 in Phytomedicine
Verified
Journal Article
Closed access
KOKai Xin Ooi
Kai Xin Ooi
CPChin Long Poo
Chin Long Poo
MSMenaga Subramaniam
Menaga Subramaniam
GCGeoffrey Cordell
Geoffrey Cordell
YLYang Mooi Lim
Yang Mooi Lim

1 July 2021 in Journal of Pain and Symptom Management
Verified
Journal Article
Closed access
CPChin Long Poo
Chin Long Poo
HDHemaniswarri Dewi Dewadas
Hemaniswarri Dewi Dewadas
FNFoong Leng Ng
Foong Leng Ng
CFChai Nien Foo
Chai Nien Foo
YLYang Mooi Lim
Yang Mooi Lim

Verified
Journal Article
Open access
PDF file
CPChin Long Poo
Chin Long Poo
MLMei Siu Lau
Mei Siu Lau
NNNur Liana Md Nasir
Nur Liana Md Nasir
NZNIK AINA SYAZANA NIK ZAINUDDIN
NIK AINA SYAZANA NIK ZAINUDDIN
MRMohd Rahimi Ashraf Abd Rahman
Mohd Rahimi Ashraf Abd Rahman
HMHUSSIN MUHAMMAD
HUSSIN MUHAMMAD
Liver diseases cause millions of deaths globally. Current treatments are often limited in effectiveness and availability, driving the search for alternatives. Herbal preparations offer potential hepatoprotective properties. Disrupted gut microbiota is linked to liver disorders. This scoping review aims to explore the effects of herbal preparations on hepatoprotective mechanisms, particularly in the context of non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and hepatic steatosis, with a focus on gut microbiota modulation. A systematic search was performed using predetermined keywords in four electronic databases (PubMed, Scopus, EMBASE, and Web of Science). A total of 55 studies were included for descriptive analysis, covering study characteristics such as disease model, dietary model, animal model, intervention details, comparators, and study outcomes. The findings of this review suggest that the hepatoprotective effects of herbal preparations are closely related to their interactions with the gut microbiota. The hepatoprotective mechanisms of herbal preparations are shown through their effects on the gut microbiota composition, intestinal barrier, and microbial metabolites, which resulted in decreased serum levels of liver enzymes and lipids, improved liver pathology, inhibition of hepatic fatty acid accumulation, suppression of inflammation and oxidative stress, reduced insulin resistance, and altered bile acid metabolism.