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Purpose: This study examined the prevalence of metabolic syndrome (MetS) in South Korean children and adolescents by gender and age and analyzed gender-specific factors associated with MetS.Methods: This study used data on children aged 10~18 from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2010 to 2015. Analyses included descriptive statistics, the independent t-test, the x2 test, and univariate logistic regression analysis (p<.050).Results: The prevalence of MetS was 4.8% in boys and 3.4% in girls. The prevalence was higher in girls up to the age of 12, but higher in boys who were 13 or older. Abdominal obesity was frequent in girls, whereas low high-density lipoprotein cholesterol (HDL-C) and elevated blood pressure were more common in boys. Higher body mass index, waist-to-height ratio, waist circumference, blood pressure, triglycerides, HDL-C, perceived "fat" body shape, and weight loss efforts were associated with MetS in both genders. Increasing age, having one meal per day, and weight maintenance were associated factors unique to boys. Fasting plasma glucose, familial medical history of low HDL-C, and perceived "thin" body shape were associated factors in girls.Conclusion: Gender and age differences should be considered in the risk assessment and prevention of MetS.
Jihea Choi; Tae Woong Yoon; Min Heui Yu; Dae Ryong Kang; Sarah Choi. Gender and age differences in the prevalence and associated factors of metabolic syndrome among children and adolescents in South Korea. Child Health Nursing Research 2021, 27, 160 -170.
AMA StyleJihea Choi, Tae Woong Yoon, Min Heui Yu, Dae Ryong Kang, Sarah Choi. Gender and age differences in the prevalence and associated factors of metabolic syndrome among children and adolescents in South Korea. Child Health Nursing Research. 2021; 27 (2):160-170.
Chicago/Turabian StyleJihea Choi; Tae Woong Yoon; Min Heui Yu; Dae Ryong Kang; Sarah Choi. 2021. "Gender and age differences in the prevalence and associated factors of metabolic syndrome among children and adolescents in South Korea." Child Health Nursing Research 27, no. 2: 160-170.
Background Socioeconomic status is associated with differences in risk factors of cardiovascular disease and increased risks of cardiovascular disease and mortality. However, it is unclear whether an association exists between cardiovascular disease and income, a common measure of socioeconomic status, among patients with hypertension. Methods and Results This population‐based longitudinal study comprised 479 359 patients aged ≥19 years diagnosed with essential hypertension. Participants were categorized by income and blood pressure levels. Primary end point was all‐cause and cardiovascular mortality and secondary end points were cardiovascular events, a composite of cardiovascular death, myocardial infarction, and stroke. Low income was significantly associated with high all‐cause (hazard ratio [HR], 1.26; 95% CI, 1.23–1.29, lowest versus highest income) and cardiovascular mortality (HR, 1.31; 95% CI, 1.25–1.38) as well as cardiovascular events (HR, 1.07; 95% CI, 1.05–1.10) in patients with hypertension after adjusting for age, sex, systolic blood pressure, body mass index, smoking status, alcohol consumption, physical activity, fasting glucose, total cholesterol, and the use of aspirin or statins. In each blood pressure category, low‐income levels were associated with high all‐cause and cardiovascular mortality and cardiovascular events. The excess risks of all‐cause and cardiovascular mortality and cardiovascular events associated with uncontrolled blood pressure were more prominent in the lowest income group. Conclusions Low income and uncontrolled blood pressure are associated with increased all‐cause and cardiovascular mortality and cardiovascular events in patients with hypertension. These findings suggest that income is an important aspect of social determinants of health that has an impact on cardiovascular outcomes in the care of hypertension.
Jeong‐Hun Shin; Mi‐Hyang Jung; Chang Hee Kwon; Chan Joo Lee; Dae‐Hee Kim; Hack‐Lyoung Kim; Woohyeun Kim; Si‐Hyuck Kang; Ju‐Hee Lee; Hyue Mee Kim; In‐Jeong Cho; Iksung Cho; Jun Hyeok Lee; Dae Ryong Kang; Hae‐Young Lee; Wook‐Jin Chung; Sang‐Hyun Ihm; Kwang Il Kim; Eun Joo Cho; Il‐Suk Sohn; Hyeon‐Chang Kim; Sungha Park; Jinho Shin; Ju Han Kim; Sung Kee Ryu; Seok‐Min Kang; Wook Bum Pyun; Myeong‐Chan Cho; Ki‐Chul Sung. Disparities in Mortality and Cardiovascular Events by Income and Blood Pressure Levels Among Patients With Hypertension in South Korea. Journal of the American Heart Association 2021, 10, e018446 .
AMA StyleJeong‐Hun Shin, Mi‐Hyang Jung, Chang Hee Kwon, Chan Joo Lee, Dae‐Hee Kim, Hack‐Lyoung Kim, Woohyeun Kim, Si‐Hyuck Kang, Ju‐Hee Lee, Hyue Mee Kim, In‐Jeong Cho, Iksung Cho, Jun Hyeok Lee, Dae Ryong Kang, Hae‐Young Lee, Wook‐Jin Chung, Sang‐Hyun Ihm, Kwang Il Kim, Eun Joo Cho, Il‐Suk Sohn, Hyeon‐Chang Kim, Sungha Park, Jinho Shin, Ju Han Kim, Sung Kee Ryu, Seok‐Min Kang, Wook Bum Pyun, Myeong‐Chan Cho, Ki‐Chul Sung. Disparities in Mortality and Cardiovascular Events by Income and Blood Pressure Levels Among Patients With Hypertension in South Korea. Journal of the American Heart Association. 2021; 10 (7):e018446.
Chicago/Turabian StyleJeong‐Hun Shin; Mi‐Hyang Jung; Chang Hee Kwon; Chan Joo Lee; Dae‐Hee Kim; Hack‐Lyoung Kim; Woohyeun Kim; Si‐Hyuck Kang; Ju‐Hee Lee; Hyue Mee Kim; In‐Jeong Cho; Iksung Cho; Jun Hyeok Lee; Dae Ryong Kang; Hae‐Young Lee; Wook‐Jin Chung; Sang‐Hyun Ihm; Kwang Il Kim; Eun Joo Cho; Il‐Suk Sohn; Hyeon‐Chang Kim; Sungha Park; Jinho Shin; Ju Han Kim; Sung Kee Ryu; Seok‐Min Kang; Wook Bum Pyun; Myeong‐Chan Cho; Ki‐Chul Sung. 2021. "Disparities in Mortality and Cardiovascular Events by Income and Blood Pressure Levels Among Patients With Hypertension in South Korea." Journal of the American Heart Association 10, no. 7: e018446.
Background It is unclear what office blood pressure (BP) is the optimal treatment target range in patients with hypertension. Methods and Results Using the Korean National Health Insurance Service database, we extracted the data on 479 359 patients with hypertension with available BP measurements and no history of cardiovascular events from 2002 to 2011. The study end point was major cardiovascular events (MACE), a composite of cardiovascular death, myocardial infarction, or stroke. This cohort study evaluated the association of BP levels (<120/<70, 120–129/70–79, 130–139/80–89, 140–149/90–99, and ≥150/≥100 mm Hg) with MACE. During a median follow‐up of 9 years, 55 401 MACE were documented in our cohort. The risk of MACE was the lowest (adjusted hazard ratio [HR], 0.79; 95% CI, 0.76–0.84) at BP level of <120/<70 mm Hg, and was the highest (HR, 1.32; 95% CI, 1.29–1.36) at ≥150/≥100 mm Hg in comparison with 130 to 139/80 to 89 mm Hg. These results were consistent in all age groups and both sexes. Among patients treated with antihypertensive medication (n=237 592, 49.5%), in comparison with a BP level of 130 to 139/80 to 89 mm Hg, the risk of MACE was significantly higher in patients with elevated BP (≥140/≥90 mm Hg), but not significantly lower in patients with BP of <130/<80 mm Hg. Low BP <120/70 mm Hg was associated with increased risk of all‐cause or cardiovascular death in all age groups. Conclusions BP level is significantly correlated with the risk of MACE in all Korean patients with hypertension. However, there were no additional benefits for MACE amongst those treated for hypertension with BP <120/70 mm Hg.
Chang Hee Kwon; Woohyeun Kim; Jeong‐Hun Shin; Chan Joo Lee; Hyeon‐Chang Kim; Si‐Hyuck Kang; Mi‐Hyang Jung; Dae‐Hee Kim; Ju‐Hee Lee; Hack Lyoung Kim; Hyue Mee Kim; In Jeong Cho; Iksung Cho; Dae Ryong Kang; Hae‐Young Lee; Wook‐Jin Chung; Sang‐Hyun Ihm; Kwang Il Kim; Eun Joo Cho; Il‐Suk Sohn; Sungha Park; Jinho Shin; Sung Kee Ryu; Seok‐Min Kang; Myeong‐Chan Cho; Ju Han Kim; Jun Hyeok Lee; Jang‐Young Kim; Wook Bum Pyun; Ki‐Chul Sung. Office Blood Pressure Range and Cardiovascular Events in Patients With Hypertension: A Nationwide Cohort Study in South Korea. Journal of the American Heart Association 2021, 10, e017890 .
AMA StyleChang Hee Kwon, Woohyeun Kim, Jeong‐Hun Shin, Chan Joo Lee, Hyeon‐Chang Kim, Si‐Hyuck Kang, Mi‐Hyang Jung, Dae‐Hee Kim, Ju‐Hee Lee, Hack Lyoung Kim, Hyue Mee Kim, In Jeong Cho, Iksung Cho, Dae Ryong Kang, Hae‐Young Lee, Wook‐Jin Chung, Sang‐Hyun Ihm, Kwang Il Kim, Eun Joo Cho, Il‐Suk Sohn, Sungha Park, Jinho Shin, Sung Kee Ryu, Seok‐Min Kang, Myeong‐Chan Cho, Ju Han Kim, Jun Hyeok Lee, Jang‐Young Kim, Wook Bum Pyun, Ki‐Chul Sung. Office Blood Pressure Range and Cardiovascular Events in Patients With Hypertension: A Nationwide Cohort Study in South Korea. Journal of the American Heart Association. 2021; 10 (7):e017890.
Chicago/Turabian StyleChang Hee Kwon; Woohyeun Kim; Jeong‐Hun Shin; Chan Joo Lee; Hyeon‐Chang Kim; Si‐Hyuck Kang; Mi‐Hyang Jung; Dae‐Hee Kim; Ju‐Hee Lee; Hack Lyoung Kim; Hyue Mee Kim; In Jeong Cho; Iksung Cho; Dae Ryong Kang; Hae‐Young Lee; Wook‐Jin Chung; Sang‐Hyun Ihm; Kwang Il Kim; Eun Joo Cho; Il‐Suk Sohn; Sungha Park; Jinho Shin; Sung Kee Ryu; Seok‐Min Kang; Myeong‐Chan Cho; Ju Han Kim; Jun Hyeok Lee; Jang‐Young Kim; Wook Bum Pyun; Ki‐Chul Sung. 2021. "Office Blood Pressure Range and Cardiovascular Events in Patients With Hypertension: A Nationwide Cohort Study in South Korea." Journal of the American Heart Association 10, no. 7: e017890.
Several studies have indicated that prenatal exposure to ambient air pollution is associated with an increased risk of gestational diabetes mellitus, hypertensive disorder during pregnancy, preterm birth, and stillbirth. However, no previous study has focused on the association between the number of pregnancy complications and exposure to ambient air pollution. To investigate the association between prenatal exposure to ambient air pollutants and the number of pregnancy complications in high-risk pregnancies. We collected data on gestational diabetes mellitus, hypertensive disorder during pregnancy, preterm birth, and stillbirth from the National Health Information Databases, provided by the Korean National Health Insurance Service.R To assess individual-level exposure to air pollutants, a spatial prediction model and area-averaging approach were used. From 2015 to 2018, data of 789,595 high-risk pregnancies were analyzed. The ratio of gestational diabetes mellitus in the country was the highest, followed by preterm birth, hypertensive disorder during pregnancy, and stillbirth. Approximately 71.7% of pregnant women (566,143) presented with one pregnancy complication in identical pregnancies, 27.5% (216,714) presented with two, and 0.9% (6738) presented with three or more. Multiple logistic regression models with adjustments for age, residence, and income variables indicated that the risk of having two or more pregnancy complications was positively associated with the exposure to higher levels of PM10 (odds ratio [OR], 1.11; 95% confidence interval [CI], 1.09–1.12) and PM2.5 (OR, 1.14; 95% CI, 1.12–1.15). The highest quartile presented higher odds of two or more pregnancy complications compared with the lower three quartiles of PM10, PM2.5, CO, NO2, and SO2 exposures (p < 0.001). The results indicate that the risk of pregnancy complications is positively associated with the exposure to the high concentrations of PM10, PM2.5, CO, NO2, and SO2.
Ju Hee Kim; Yoon Young Choi; Soo-In Yoo; Dae Ryong Kang. Association between ambient air pollution and high-risk pregnancy: A 2015–2018 national population-based cohort study in Korea. Environmental Research 2021, 197, 110965 .
AMA StyleJu Hee Kim, Yoon Young Choi, Soo-In Yoo, Dae Ryong Kang. Association between ambient air pollution and high-risk pregnancy: A 2015–2018 national population-based cohort study in Korea. Environmental Research. 2021; 197 ():110965.
Chicago/Turabian StyleJu Hee Kim; Yoon Young Choi; Soo-In Yoo; Dae Ryong Kang. 2021. "Association between ambient air pollution and high-risk pregnancy: A 2015–2018 national population-based cohort study in Korea." Environmental Research 197, no. : 110965.
Background It is known in some studies that higher the LDL-C, the greater the risk of developing cardiovascular disease. However, studies of the causal effects between LDL-C and hypertension are limited by their observational study design, and genetic epidemiology studies of associations between LDL-C and hypertension are lacking, as are studies using data for Koreans. In this study, we confirmed the causal effect of LDL-C on hypertension using Korean chip data. Method The epidemiology and genotype data were collected from the Korean Genome and Epidemiology Study conducted by the Korea National Institute of Health and covered 20,701 subjects. Single-nucleotide polymorphisms associated with LDL-C were selected (p-value < 5 × 10− 8) from the Global Lipids Genetics Consortium database, and Mendelian randomization analysis (MRA) was performed with counted genetic risk scores and weighted genetic risk scores (WGRSs) for 24 single-nucleotide polymorphisms. Result The assumptions for MRA were statistically confirmed, and WGRSs showed a strong association with LDL-C. Interestingly, while the relationship between LDL-C and hypertension was not statistically significant in the observational study, MRA study demonstrated that the risk of hypertension increased as LDL-C increased in both men and women. Conclusions The results of this study confirmed that the relationship between LDL-C and hypertension is greatly influenced by genetic information.
Tae-Hwa Go; Kyeong Im Kwak; Ji-Yun Jang; Minheui Yu; Hye Sim Kim; Jang Young Kim; Sang Baek Koh; Dae Ryong Kang. Inference of a causal relation between low-density lipoprotein cholesterol and hypertension using mendelian randomization analysis. Clinical Hypertension 2021, 27, 1 -9.
AMA StyleTae-Hwa Go, Kyeong Im Kwak, Ji-Yun Jang, Minheui Yu, Hye Sim Kim, Jang Young Kim, Sang Baek Koh, Dae Ryong Kang. Inference of a causal relation between low-density lipoprotein cholesterol and hypertension using mendelian randomization analysis. Clinical Hypertension. 2021; 27 (1):1-9.
Chicago/Turabian StyleTae-Hwa Go; Kyeong Im Kwak; Ji-Yun Jang; Minheui Yu; Hye Sim Kim; Jang Young Kim; Sang Baek Koh; Dae Ryong Kang. 2021. "Inference of a causal relation between low-density lipoprotein cholesterol and hypertension using mendelian randomization analysis." Clinical Hypertension 27, no. 1: 1-9.
Yoon Young Choi; Hoyeon Jeong; Jun Hyeok Lee; Ki Chul Sung; Jeong-Hun Shin; Hyeon Chang Kim; Jang Young Kim; Dae Ryong Kang. Cardiovascular Disease Prediction Model in Patients with Hypertension Using Deep Learning: Analysis of the National Health Insurance Service Database from Republic of Korea. CardioMetabolic Syndrome Journal 2021, 1, 1 .
AMA StyleYoon Young Choi, Hoyeon Jeong, Jun Hyeok Lee, Ki Chul Sung, Jeong-Hun Shin, Hyeon Chang Kim, Jang Young Kim, Dae Ryong Kang. Cardiovascular Disease Prediction Model in Patients with Hypertension Using Deep Learning: Analysis of the National Health Insurance Service Database from Republic of Korea. CardioMetabolic Syndrome Journal. 2021; 1 ():1.
Chicago/Turabian StyleYoon Young Choi; Hoyeon Jeong; Jun Hyeok Lee; Ki Chul Sung; Jeong-Hun Shin; Hyeon Chang Kim; Jang Young Kim; Dae Ryong Kang. 2021. "Cardiovascular Disease Prediction Model in Patients with Hypertension Using Deep Learning: Analysis of the National Health Insurance Service Database from Republic of Korea." CardioMetabolic Syndrome Journal 1, no. : 1.
Ji Hye Huh; Dae Ryong Kang; Jang Young Kim; Kwang Kon Koh; Taskforce Team of the Metabolic Syndrome Fact Sheet of the Korean Society of Cardiometabolic Syndrome. Metabolic Syndrome Fact Sheet 2021: Executive Report. CardioMetabolic Syndrome Journal 2021, 1, 1 .
AMA StyleJi Hye Huh, Dae Ryong Kang, Jang Young Kim, Kwang Kon Koh, Taskforce Team of the Metabolic Syndrome Fact Sheet of the Korean Society of Cardiometabolic Syndrome. Metabolic Syndrome Fact Sheet 2021: Executive Report. CardioMetabolic Syndrome Journal. 2021; 1 ():1.
Chicago/Turabian StyleJi Hye Huh; Dae Ryong Kang; Jang Young Kim; Kwang Kon Koh; Taskforce Team of the Metabolic Syndrome Fact Sheet of the Korean Society of Cardiometabolic Syndrome. 2021. "Metabolic Syndrome Fact Sheet 2021: Executive Report." CardioMetabolic Syndrome Journal 1, no. : 1.
(1) Background: The health implications associated with the metabolically healthy obese (MHO) phenotype, in particular related to symptoms of depression, are still not clear. the purpose of this study is to check whether depression and metabolic status are relevant by classifying them into four groups in accordance with the MHO diagnostic standard. Other impressions seen were the differences between sexes and the effects of the MHO on the occurrence of depression. (2) Methods: A sample of 3,586,492 adult individuals from the National Health Insurance Database of Korea was classified into four categories by their metabolic status and body mass index: (1) metabolically healthy non-obese (MHN); (2) metabolically healthy obese (MHO); (3) metabolically unhealthy non-obese (MUN); and (4) metabolically unhealthy obese (MUO). Participants were followed for six to eight years for new incidences of depression. The statistical significance of the general characteristics of the four groups, as well as the mean differences in metabolic syndrome risk factors, was assessed with the use of a one-way analysis of variance (ANOVA). (3) Results: The MHN ratio in women was higher than in men (men 39.3%, women 55.2%). In both men and women, depression incidence was the highest among MUO participants (odds ratio (OR) = 1.01 in men; OR = 1.09 in women). It was concluded as well that, among the risk factors of metabolic syndrome, waist circumference was the most related to depression. Among the four groups, the MUO phenotype was the most related to depression. Furthermore, in women participants, MHO is also related to a higher risk of depressive symptoms. These findings indicate that MHO is not a totally benign condition in relation to depression in women. (4) Conclusion: Therefore, reducing metabolic syndrome and obesity patients in Korea will likely reduce the incidence of depression.
Yongseok Seo; Seungyeon Lee; Joung-Sook Ahn; Seongho Min; Min-Hyuk Kim; Jang-Young Kim; Dae Ryong Kang; Sangwon Hwang; Phor Vicheka; Jinhee Lee. Association of Metabolically Healthy Obesity and Future Depression: Using National Health Insurance System Data in Korea from 2009–2017. International Journal of Environmental Research and Public Health 2020, 18, 63 .
AMA StyleYongseok Seo, Seungyeon Lee, Joung-Sook Ahn, Seongho Min, Min-Hyuk Kim, Jang-Young Kim, Dae Ryong Kang, Sangwon Hwang, Phor Vicheka, Jinhee Lee. Association of Metabolically Healthy Obesity and Future Depression: Using National Health Insurance System Data in Korea from 2009–2017. International Journal of Environmental Research and Public Health. 2020; 18 (1):63.
Chicago/Turabian StyleYongseok Seo; Seungyeon Lee; Joung-Sook Ahn; Seongho Min; Min-Hyuk Kim; Jang-Young Kim; Dae Ryong Kang; Sangwon Hwang; Phor Vicheka; Jinhee Lee. 2020. "Association of Metabolically Healthy Obesity and Future Depression: Using National Health Insurance System Data in Korea from 2009–2017." International Journal of Environmental Research and Public Health 18, no. 1: 63.
Aims To investigate sex differences in the association of metabolic syndrome (MetS) and/or low-density lipoprotein cholesterol (LDL-C) with the incidence of cardiovascular and cerebrovascular disease (CCVD). Methods and results A total of 4 702 458 individuals, aged between 40 and 70, without a previous diagnosis of CCVD, underwent at least two health screenings between 2009 and 2011. Of them, 4 193 878 individuals (48.6% women) fulfilled the study requirements. The main outcome measured was the incidence of CCVD. By the end of 2017, 68 921 CCVD events occurred. Men in high LDL-C only, MetS only, and both MetS and high LDL-C groups had higher risks of CCVD. Women in MetS only and both MetS and high LDL-C groups, but not those in high LDL-C only group, had higher risks of CCVD than those in the reference group. The effect of the interaction between the presence of MetS and high LDL-C levels on the primary outcome was found among women (P for interaction 0.016) but not among men (P for interaction 0.897). A combination of MetS and LDL-C > 3.4 mmol/L increased the risk of CCVD as compared to MetS or LDL-C > 3.4 mmol/L alone in both men and women. Conclusions Metabolic syndrome confers an increased risk of CCVD irrespective of sexes; LDL-C > 3.4 mmol/L alone has a greater influence on CCVD occurrence in men than in women. Metabolic syndrome and high LDL-C beget a synergistically detrimental impact on the incidence of CCVD in both men and women. Treatment of dyslipidaemia and metabolic syndrome should be tailored according to patient characteristics.
Su Yong Kim; Tae-Hwa Go; Jun Hyeok Lee; Jin Sil Moon; Dae Ryong Kang; Se Jin Bae; Se-Eun Kim; Sang Jun Lee; Dong-Hyuk Cho; Young Jun Park; Young Jin Youn; Jang Young Kim; Sung Gyun Ahn. Differential association of metabolic syndrome and low-density lipoprotein cholesterol with incident cardiovascular disease according to sex among Koreans: a national population-based study. European Journal of Preventive Cardiology 2020, 1 .
AMA StyleSu Yong Kim, Tae-Hwa Go, Jun Hyeok Lee, Jin Sil Moon, Dae Ryong Kang, Se Jin Bae, Se-Eun Kim, Sang Jun Lee, Dong-Hyuk Cho, Young Jun Park, Young Jin Youn, Jang Young Kim, Sung Gyun Ahn. Differential association of metabolic syndrome and low-density lipoprotein cholesterol with incident cardiovascular disease according to sex among Koreans: a national population-based study. European Journal of Preventive Cardiology. 2020; ():1.
Chicago/Turabian StyleSu Yong Kim; Tae-Hwa Go; Jun Hyeok Lee; Jin Sil Moon; Dae Ryong Kang; Se Jin Bae; Se-Eun Kim; Sang Jun Lee; Dong-Hyuk Cho; Young Jun Park; Young Jin Youn; Jang Young Kim; Sung Gyun Ahn. 2020. "Differential association of metabolic syndrome and low-density lipoprotein cholesterol with incident cardiovascular disease according to sex among Koreans: a national population-based study." European Journal of Preventive Cardiology , no. : 1.
Concentrations of toxic chemicals in mothers highly correlate with those in their children; moreover, the levels are higher in children than in mothers. Non-persistent chemicals with a short half-life including phthalate metabolites, bisphenol A (BPA), triclosan (TCS), and parabens are metabolized and excreted through urine. Therefore, we assessed the urine concentrations of phthalate metabolites, BPA, TCS, and parabens; correlated the concentrations with exposure levels; and assessed the within-individual variability of these chemicals in mothers and their infants. We collected 225 and 71 samples from 45 mothers and 36 infants, respectively. For the variability analysis, 189 and 42 samples were collected from nine mothers and their infants, respectively. The median concentrations of phthalate metabolites in the mothers and infants were 0.53–26.2 and 0.81–61.8 μg/L, respectively, and those of BPA, TCS, and parabens were 0.24–76.3 and 2.06–12.5 μg/L, respectively. The concentrations of monoethyl phthalate (MEP), mono-N-butyl phthalate (MnBP), mono-isobutyl phthalate (MiBP), and BPA in the mothers were positively correlated with those in infants (0.45, 0.62, and 0.89, respectively; p < 0.05), whereas toxic chemical concentrations in infants were higher than those in the mothers. With respect to the within-individual intraclass correlation coefficient (ICC), the first morning void (FMV) of the mothers had high ICCs for all chemicals (range: 0.72–0.99), except for BPA, monobenzyl phthalate (MBzP), and monocarboxyoctyl phthalate (MCOP). The ICC values of most chemicals were moderate to high (range: 0.34–0.99) in the first morning void. However, there were different patterns of ICCs in the infants. These findings indicate the importance of mother–infant pair studies and the necessity of research in infants, as they have different exposure sources and pathways from adults.
Ju Hee Kim; Dae Ryong Kang; Jung Min Kwak; Jung Kuk Lee. Concentration and Variability of Urinary Phthalate Metabolites, Bisphenol A, Triclosan, and Parabens in Korean Mother–Infant Pairs. Sustainability 2020, 12, 8516 .
AMA StyleJu Hee Kim, Dae Ryong Kang, Jung Min Kwak, Jung Kuk Lee. Concentration and Variability of Urinary Phthalate Metabolites, Bisphenol A, Triclosan, and Parabens in Korean Mother–Infant Pairs. Sustainability. 2020; 12 (20):8516.
Chicago/Turabian StyleJu Hee Kim; Dae Ryong Kang; Jung Min Kwak; Jung Kuk Lee. 2020. "Concentration and Variability of Urinary Phthalate Metabolites, Bisphenol A, Triclosan, and Parabens in Korean Mother–Infant Pairs." Sustainability 12, no. 20: 8516.
Aim We investigated the associations between hemoglobin glycation index (HGI) and incident chronic kidney disease (CKD) in treatment-naïve subjects with prediabetes or diabetes. We conducted a prospective cohort study comprising 2,187 subjects with prediabetes or diabetes. HGI was calculated as the difference between the measured and predicted values of HbA1c using the linear relationship between HbA1c level and fasting plasma glucose levels. Incident CKD was considered if eGFR decreased to < 60 mL/min/1.73 m2 and by > 25% from the baseline value during follow up. The hazard ratios (HRs) for incident CKD were calculated using Cox proportional hazards regression models. The overall prevalence of CKD was 15.3% (n=335) during the 10-year follow-up period. The prevalence of CKD increased significantly from the low to the high HGI groups. In the multivariate analysis, the highest HGI group showed the highest adjusted HR for incident CKD (HR, 1.57; 95% confidence interval, 1.06–2.34), and this remained significant even after adjusting for the HbA1c level. High HGI was associated with an increased risk of incident CKD among treatment-naïve subjects with prediabetes or diabetes, suggesting that HGI may be used to predict CKD in these patients regardless of HbA1c levels.
Wonjin Kim; Taehwa Go; Dae Ryong Kang; Eun Jig Lee; Ji Hye Huh. Hemoglobin glycation index is associated with incident chronic kidney disease in subjects with impaired glucose metabolism: A 10-year longitudinal cohort study. Journal of Diabetes and its Complications 2020, 35, 107760 .
AMA StyleWonjin Kim, Taehwa Go, Dae Ryong Kang, Eun Jig Lee, Ji Hye Huh. Hemoglobin glycation index is associated with incident chronic kidney disease in subjects with impaired glucose metabolism: A 10-year longitudinal cohort study. Journal of Diabetes and its Complications. 2020; 35 (1):107760.
Chicago/Turabian StyleWonjin Kim; Taehwa Go; Dae Ryong Kang; Eun Jig Lee; Ji Hye Huh. 2020. "Hemoglobin glycation index is associated with incident chronic kidney disease in subjects with impaired glucose metabolism: A 10-year longitudinal cohort study." Journal of Diabetes and its Complications 35, no. 1: 107760.
Background: The aim of this study was to evaluate the safety and efficacy of a flowable hemostatic matrix, and their effects for postoperative pancreatic fistula (POPF) after pancreatectomy. Methods: This was a randomized, clinical, single-center, single-blind (participant), non-inferiority, phase IV, and parallel-group trial. The primary endpoint was the incidence of POPF. The secondary endpoints were risk factors for POPF, drain removal days, incidence of complication, 90-day mortality, and length of hospital stay. Results: This study evaluated a total of 53 patients, of whom 26 patients were in the intervention group (flowable hemostatic matrix) and 27 patients were in the control group (thrombin-coated collagen patch). POPF was more common in the control group than in the intervention group (59.3% vs. 30.8%, p = 0.037). Among participants who underwent distal pancreatectomy, POPF (33.3% vs. 92.3%, p = 0.004), and clinically relevant POPF (8.3% vs. 46.2%, p = 0.027) was more common in the control group. A multivariate logistic regression model identified flowable hemostatic matrix use as an independent negative risk factor for POPF, especially in cases of distal pancreatectomy (DP) (odds ratio 17.379, 95% confidential interval 1.453–207.870, p = 0.024). Conclusion: Flowable hemostatic matrix application is a simple, feasible, and effective method of preventing POPF after pancreatectomy, especially for patients with DP. Non-inferiority was demonstrated in the efficacy of preventing POPF in the intervention group compared to the control group.
Yejong Park; Jae Hyung Ko; Dae Ryong Kang; Jun Hyeok Lee; Dae Wook Hwang; Jae Hoon Lee; Woohyung Lee; Jaewoo Kwon; Si-Nae Park; Ki-Byung Song; Song Cheol Kim. Effect of Flowable Thrombin-Containing Collagen-Based Hemostatic Matrix for Preventing Pancreatic Fistula after Pancreatectomy: A Randomized Clinical Trial. Journal of Clinical Medicine 2020, 9, 3085 .
AMA StyleYejong Park, Jae Hyung Ko, Dae Ryong Kang, Jun Hyeok Lee, Dae Wook Hwang, Jae Hoon Lee, Woohyung Lee, Jaewoo Kwon, Si-Nae Park, Ki-Byung Song, Song Cheol Kim. Effect of Flowable Thrombin-Containing Collagen-Based Hemostatic Matrix for Preventing Pancreatic Fistula after Pancreatectomy: A Randomized Clinical Trial. Journal of Clinical Medicine. 2020; 9 (10):3085.
Chicago/Turabian StyleYejong Park; Jae Hyung Ko; Dae Ryong Kang; Jun Hyeok Lee; Dae Wook Hwang; Jae Hoon Lee; Woohyung Lee; Jaewoo Kwon; Si-Nae Park; Ki-Byung Song; Song Cheol Kim. 2020. "Effect of Flowable Thrombin-Containing Collagen-Based Hemostatic Matrix for Preventing Pancreatic Fistula after Pancreatectomy: A Randomized Clinical Trial." Journal of Clinical Medicine 9, no. 10: 3085.
The association between blood pressure (BP) defined by the 2017 American College of Cardiology/American Heart Association Hypertension Clinical Practice Guidelines with cardiovascular disease (CVD) and chronic kidney disease in patients with diabetes mellitus remains unclear. This study used the National Health Insurance Database of Korea that has health information of 8 922 940 persons who were screened from 2009 to 2014. We determined the BP status of 490 352 diabetes mellitus: level 1 (systolic <120 mm Hg and diastolic <80 mm Hg), level 2 (systolic 120–129 mm Hg and diastolic <80 mm Hg), level 3 (systolic 130–139 mm Hg or diastolic 80–89 mm Hg), and level 4 (systolic ≥140 mm Hg or diastolic ≥90 mm Hg). Over a mean follow-up of 5 years, 6508 CVD events (1.3%), 14 318 cases of chronic kidney disease development (2.9%), 9094 cerebrovascular events (2.0%), and 1150 CVD mortalities (0.2%) occurred. Compared with people with BP levels 1, the adjusted hazard ratios for CVD in people with BP levels 2, 3, and 4 were 1.07 (95% CI, 0.98–1.16), 1.12 (95% CI, 1.04–1.20), and 1.17 (95% CI, 1.08–1.26), respectively. There were also increased risks of chronic kidney disease (1.18 [95% CI, 1.12–1.24] and 1.22 [95% CI, 1.15–1.29]), cerebrovascular disease (1.21 [95% CI, 1.14–1.29] and 1.52 [95% CI, 1.42–1.63]), and CVD mortality (1.31 [95% CI, 1.09–1.56] and 1.91 [95% CI, 1.58–2.32]) among subjects with BP levels 3 and 4 compared with those with BP level 1. These findings provide evidence supporting the 2017 American College of Cardiology/American Heart Association Hypertension Clinical Practice Guidelines for BP targets in diabetes mellitus patients.
Yong Tae Kim; Hyung Joon Chung; Bo Ram Park; Yeon Yong Kim; Jun Hyeok Lee; Dae Ryong Kang; Jang-Young Kim; Mi Young Lee. Risk of Cardiovascular Disease and Chronic Kidney Disease According to 2017 Blood Pressure Categories in Diabetes Mellitus. Hypertension 2020, 76, 766 -775.
AMA StyleYong Tae Kim, Hyung Joon Chung, Bo Ram Park, Yeon Yong Kim, Jun Hyeok Lee, Dae Ryong Kang, Jang-Young Kim, Mi Young Lee. Risk of Cardiovascular Disease and Chronic Kidney Disease According to 2017 Blood Pressure Categories in Diabetes Mellitus. Hypertension. 2020; 76 (3):766-775.
Chicago/Turabian StyleYong Tae Kim; Hyung Joon Chung; Bo Ram Park; Yeon Yong Kim; Jun Hyeok Lee; Dae Ryong Kang; Jang-Young Kim; Mi Young Lee. 2020. "Risk of Cardiovascular Disease and Chronic Kidney Disease According to 2017 Blood Pressure Categories in Diabetes Mellitus." Hypertension 76, no. 3: 766-775.
We evaluated clinical and nutritional outcomes according to multidisciplinary team involvement in nutrition support in a regional trauma intensive care unit (TICU). We retrospectively compared the outcomes for 339 patients admitted to the TICU for >5 days depending on nutrition support team (NST) involvement (n=176) and non-NST involvement (n=163). The mean age and injury severity score (ISS) were 57.3±16.7 years and 18.6±9.7, respectively. Fifty-three patients (15.6%) had shock on admission and 182 (53.7%) underwent surgery during TICU admission. Some patients were admitted to neurosurgery (46%), general surgery (35.4%), and other (18.6%) departments. There were significant differences in the ISS, Acute Physiology and Chronic Health Evaluation (APACHE) II score, shock on TICU admission, and initial laboratory results. After propensity score matching, the total delivered/required caloric ratio and total delivered/required protein ratio were significantly higher in the NST group than in the non-NST group (calorie: 80.4% vs. 66.7%, P=0.007; protein: 93.1% vs. 68.3%, P<0.001). The NST group had an adequate protein supply more frequently than the non-NST group (protein: 48.0% vs. 25.8%, P=0.002). There was no significant difference in survival, even after adjustment for risk factors using Cox proportional hazard analysis. The results of our study suggest that multidisciplinary team involvement in nutrition support in TICU patients may improve nutritional, but not clinical, outcomes.
Eunsuk Oh; Hongjin Shim; Hyon Ju Yon; Jin Sil Moon; Dae Ryong Kang; Ji Young Jang. Effectiveness of a multidisciplinary team for nutrition support in a trauma intensive care unit. Acute and Critical Care 2020, 35, 142 -148.
AMA StyleEunsuk Oh, Hongjin Shim, Hyon Ju Yon, Jin Sil Moon, Dae Ryong Kang, Ji Young Jang. Effectiveness of a multidisciplinary team for nutrition support in a trauma intensive care unit. Acute and Critical Care. 2020; 35 (3):142-148.
Chicago/Turabian StyleEunsuk Oh; Hongjin Shim; Hyon Ju Yon; Jin Sil Moon; Dae Ryong Kang; Ji Young Jang. 2020. "Effectiveness of a multidisciplinary team for nutrition support in a trauma intensive care unit." Acute and Critical Care 35, no. 3: 142-148.
Estimating the lung cancer disease burden can provide evidence for public health practitioners, researchers, and policymakers. This study uses claim data from lung cancer patients for 2006–2015 from the Korean National Health Insurance Service to estimate the lung cancer burdens attributable to residential radon in Korea using disability-adjusted life years (DALY) and patients' annual economic burden with societal perspectives using the cost-of-illness (COI) method. The number of patients increased during our study period (from 35,866 to 59,168). The disease burden and that attributable to residential radon, respectively, increased from 517.57 to 695.74 and 64.62 (95%; CIs 61.33–67.69) to 86.99 (95%; CIs 82.7–91.1) DALYs per 100,000 patients. The percentage of years lost due to disability among the DALY doubled from 8% to 17%. The cost for all the patients was US$2.33 billion, with US$292 (95%; CIs 278–306) million attributable to residential radon. During the last decade, the lung cancer disease burden increased by 1.34 times, with a doubled percentage of non-fatal burden and average annual growth rate of 9.5% of the total cost. Hence, the burden and cost of lung cancer in Korean provinces have been steadily increasing. The findings could be used as input data for future cost-effectiveness analysis of policies regarding radon reduction.
Juhwan Noh; Heeseon Jang; Jaelim Cho; Dae Ryong Kang; Tae Hyun Kim; Dong Chun Shin; Changsoo Kim. Estimating the disease burden of lung cancer attributable to residential radon exposure in Korea during 2006–2015: A socio-economic approach. Science of The Total Environment 2020, 749, 141573 .
AMA StyleJuhwan Noh, Heeseon Jang, Jaelim Cho, Dae Ryong Kang, Tae Hyun Kim, Dong Chun Shin, Changsoo Kim. Estimating the disease burden of lung cancer attributable to residential radon exposure in Korea during 2006–2015: A socio-economic approach. Science of The Total Environment. 2020; 749 ():141573.
Chicago/Turabian StyleJuhwan Noh; Heeseon Jang; Jaelim Cho; Dae Ryong Kang; Tae Hyun Kim; Dong Chun Shin; Changsoo Kim. 2020. "Estimating the disease burden of lung cancer attributable to residential radon exposure in Korea during 2006–2015: A socio-economic approach." Science of The Total Environment 749, no. : 141573.
Introduction: Non-Daily Smoking (NDS), which is increasingly prevalent worldwide, has not yet attracted as much attention as has daily smoking in Asia. The aims of this study were to identify trends in the prevalence of NDS and to compare characteristics by age, gender, and mental health indicators such as depression, suicidality, and alcohol consumption in South Korea. Methods: We included 33,806 adults (aged ≥ 19 years) who participated in the Korean National Health and Nutrition Examination Survey (KNHNES) from 2010 to 2015. The dataset includes self-reported medical history and questionnaires that explore depression, suicidality, and alcohol use, which are known to be highly related to smoking. We divided the respondents into four groups according to smoking status: Never Smoking (NS, N = 20,270); Past Smoking (PS = 6835); Daily Smoking (DS = 5927), who reported smoking every day; and Non-Daily Smoking (NDS = 774), who reported that they sometimes smoke. Results: Increased NDS prevalence is observed in most age groups in both male and female adults despite the prevalence of total smoking and daily smoking gradually decreasing. Depression and suicidality were significantly more prevalent in the NDS than the NS group (Depression Odds ratio, OR = 1.72, 95% Confidence interval, CI = 1.31–2.26; Suicidality OR = 3.14, 95% CI = 1.40–7.02). NDS is also associated with a higher frequency of binge drinking and alcohol use disorder than NS (OR = 4.17, 95% CI = 3.49–4.99). Conclusions: This study suggests that more concern is warranted for NDS given the increasing prevalence and characteristics of poor mental health in NDS respondents.
Yunna Kwan; Hye Sim Kim; Dae Ryong Kang; And Tae Hui Kim. Trend in the Prevalence of Non-Daily Smoking and Their Relationship with Mental Health Using the Korea Health and Nutrition Examination Survey. International Journal of Environmental Research and Public Health 2020, 17, 3396 .
AMA StyleYunna Kwan, Hye Sim Kim, Dae Ryong Kang, And Tae Hui Kim. Trend in the Prevalence of Non-Daily Smoking and Their Relationship with Mental Health Using the Korea Health and Nutrition Examination Survey. International Journal of Environmental Research and Public Health. 2020; 17 (10):3396.
Chicago/Turabian StyleYunna Kwan; Hye Sim Kim; Dae Ryong Kang; And Tae Hui Kim. 2020. "Trend in the Prevalence of Non-Daily Smoking and Their Relationship with Mental Health Using the Korea Health and Nutrition Examination Survey." International Journal of Environmental Research and Public Health 17, no. 10: 3396.
Residential radon exposure and cigarette smoking are the two most important risk factors for lung cancer. The combined effects thereof were evaluated in a multi-center matched case-control study in South Korea. A total of 1038 participants were included, comprising 519 non-small cell lung cancer cases and 519 age- and sex- matched community-based controls. Residential radon levels were measured for all participants. Multivariate logistic regression was used to calculate odds ratios (OR) for lung cancer according to radon exposure (high ≥ 100 Bq/m3 vs. low < 100 Bq/m3), smoking status, and combinations of the two after adjusting for age, sex, indoor hours, and other housing information. The median age of the participants was 64 years, and 51.3% were women. The adjusted ORs (95% confidence intervals [CIs]) for high radon and cigarette smoking were 1.56 (1.03–2.37) and 2.53 (1.60–3.99), respectively. When stratified according to combinations of radon exposure and smoking status, the adjusted ORs (95% CIs) for lung cancer in high-radon non-smokers, low-radon smokers, and high-radon smokers were 1.40 (0.81–2.43), 2.42 (1.49–3.92), and 4.27 (2.14–8.52), respectively, with reference to low-radon non-smokers. Both residential radon and cigarette smoking were associated with increased odds for lung cancer, and the difference in ORs according to radon exposure was much greater in smokers than in non-smokers.
Eung Joo Park; Hokyou Lee; Hyeon Chang Kim; Seung Soo Sheen; Sang Baek Koh; Ki Soo Park; Nam Han Cho; Cheol-Min Lee; Dae Ryong Kang. Residential Radon Exposure and Cigarette Smoking in Association with Lung Cancer: A Matched Case-Control Study in Korea. International Journal of Environmental Research and Public Health 2020, 17, 2946 .
AMA StyleEung Joo Park, Hokyou Lee, Hyeon Chang Kim, Seung Soo Sheen, Sang Baek Koh, Ki Soo Park, Nam Han Cho, Cheol-Min Lee, Dae Ryong Kang. Residential Radon Exposure and Cigarette Smoking in Association with Lung Cancer: A Matched Case-Control Study in Korea. International Journal of Environmental Research and Public Health. 2020; 17 (8):2946.
Chicago/Turabian StyleEung Joo Park; Hokyou Lee; Hyeon Chang Kim; Seung Soo Sheen; Sang Baek Koh; Ki Soo Park; Nam Han Cho; Cheol-Min Lee; Dae Ryong Kang. 2020. "Residential Radon Exposure and Cigarette Smoking in Association with Lung Cancer: A Matched Case-Control Study in Korea." International Journal of Environmental Research and Public Health 17, no. 8: 2946.
Atypical chest pain and diabetic autonomic neuropathy attract less clinical attention, leading to underdiagnosis and delayed treatment. To evaluate the long-term clinical impact of atypical chest pain and diabetes mellitus (DM), we categorized 11,159 patients with acute myocardial infarction (AMI) from the Korea AMI-National Institutes of Health between November 2011 and December 2015 into four groups (atypical DM, atypical non-DM, typical DM, and typical non-DM). The primary endpoint was defined as patient-oriented composite endpoint (POCE) at 2 years including all-cause death, any myocardial infarction (MI), and any revascularization. Patients with atypical chest pain showed higher 2-year mortality than those with typical chest pain in both DM (29.5% vs. 11.4%, p < 0.0001) and non-DM (20.4% vs. 6.3%, p < 0.0001) groups. The atypical DM group had the highest risks of POCE (hazard ratio (HR) 1.76, 95% confidence interval (CI) 1.48–2.10), all-cause death (HR 2.23, 95% CI 1.80–2.76) and any MI (HR 2.34, 95% CI 1.51–3.64) in the adjusted model. In conclusion, atypical chest pain was significantly associated with mortality in patients with AMI. Among four groups, the atypical DM group showed the worst clinical outcomes at 2 years. Application of rapid rule in/out AMI protocols would be beneficial to improve clinical outcomes.
Jun-Won Lee; Jin Sil Moon; Dae Ryong Kang; Sang Jun Lee; Jung-Woo Son; Young Jin Youn; Sung Gyun Ahn; Min-Soo Ahn; Jang-Young Kim; Byung-Su Yoo; Seung-Hwan Lee; Ju Han Kim; Myung Ho Jeong; Jong-Seon Park; Shung Chull Chae; Seung Ho Hur; Myeng-Chan Cho; Seung Woon Rha; Kwang Soo Cha; Jei Keon Chae; Dong-Ju Choi; In Whan Seong; Seok Kyu Oh; Jin Yong Hwang; Junghan Yoon; Myung Ho Jung. Clinical Impact of Atypical Chest Pain and Diabetes Mellitus in Patients with Acute Myocardial Infarction from Prospective KAMIR-NIH Registry. Journal of Clinical Medicine 2020, 9, 505 .
AMA StyleJun-Won Lee, Jin Sil Moon, Dae Ryong Kang, Sang Jun Lee, Jung-Woo Son, Young Jin Youn, Sung Gyun Ahn, Min-Soo Ahn, Jang-Young Kim, Byung-Su Yoo, Seung-Hwan Lee, Ju Han Kim, Myung Ho Jeong, Jong-Seon Park, Shung Chull Chae, Seung Ho Hur, Myeng-Chan Cho, Seung Woon Rha, Kwang Soo Cha, Jei Keon Chae, Dong-Ju Choi, In Whan Seong, Seok Kyu Oh, Jin Yong Hwang, Junghan Yoon, Myung Ho Jung. Clinical Impact of Atypical Chest Pain and Diabetes Mellitus in Patients with Acute Myocardial Infarction from Prospective KAMIR-NIH Registry. Journal of Clinical Medicine. 2020; 9 (2):505.
Chicago/Turabian StyleJun-Won Lee; Jin Sil Moon; Dae Ryong Kang; Sang Jun Lee; Jung-Woo Son; Young Jin Youn; Sung Gyun Ahn; Min-Soo Ahn; Jang-Young Kim; Byung-Su Yoo; Seung-Hwan Lee; Ju Han Kim; Myung Ho Jeong; Jong-Seon Park; Shung Chull Chae; Seung Ho Hur; Myeng-Chan Cho; Seung Woon Rha; Kwang Soo Cha; Jei Keon Chae; Dong-Ju Choi; In Whan Seong; Seok Kyu Oh; Jin Yong Hwang; Junghan Yoon; Myung Ho Jung. 2020. "Clinical Impact of Atypical Chest Pain and Diabetes Mellitus in Patients with Acute Myocardial Infarction from Prospective KAMIR-NIH Registry." Journal of Clinical Medicine 9, no. 2: 505.
Tae-Hwa Go; Dae Ryong Kang. Basic Concepts of a Mendelian Randomization Approach. Cardiovascular Prevention and Pharmacotherapy 2020, 2, 24 .
AMA StyleTae-Hwa Go, Dae Ryong Kang. Basic Concepts of a Mendelian Randomization Approach. Cardiovascular Prevention and Pharmacotherapy. 2020; 2 (1):24.
Chicago/Turabian StyleTae-Hwa Go; Dae Ryong Kang. 2020. "Basic Concepts of a Mendelian Randomization Approach." Cardiovascular Prevention and Pharmacotherapy 2, no. 1: 24.
β-blockers (BBs) are considered primary therapy in stable heart failure (HF) with reduced ejection fraction (HFrEF) without atrial fibrillation (AF); evidence-based benefits of BB on outcome have been documented. However, BBs have not been shown to improve mortality or reduce hospital admissions in HF patients with AF. This study assessed the relationship between BBs at discharge and relevant clinical outcomes in acute heart failure (AHF) patients with AF. From the Korean Acute Heart Failure Registry, 936 HFrEF and 639 HF patients with preserved ejection fraction (HFpEF) and AF were selected. Propensity score (PS) matching accounted for BB selection bias when assessing associations. BB-untreated patients in the overall cohort of HFrEF and HFpEF had greater deteriorated clinical and laboratory characteristics. In the 670 PS-matched cohort of HFrEF patients, incidences of all clinical events at 60 days and 1 year were not different according to use of BBs. In the 470 PS-matched cohort of HFpEF, rehospitalization and composite outcome at 6 months and 1 year more frequently occurred in non-users of BBs. After adjusting for covariates in the multivariable Cox model of matched cohorts, BB was not associated with clinical outcomes at 60 days and 1 year in HFrEF with AF patients. In HFpEF patients with AF, BB use was associated with reduced 6-month (hazard ratio [HR], 0.38; 95% confidence interval [CI], 0.20-0.74) and 1-year rehospitalization (HR, 0.53; 95% CI, 0.34-0.82). In the HFrEF with AF PS-matched cohort, the use of BBs at discharge was not associated with clinical outcome. However, in HFpEF with AF, the use of BB was associated with reduced rehospitalization during the 6-month and 1-year follow up.
Min-Soo Ahn; Byung-Su Yoo; Jung-Woo Son; Min Heui Yu; Dae Ryong Kang; Hae-Young Lee; Eun-Seok Jeon; Jae-Joong Kim; Shung Chull Chae; Sang Hong Baek; Seok-Min Kang; Dong-Ju Choi; Kye Hun Kim; Myeong-Chan Cho; Seong Yoon Kim. Beta-blocker Therapy at Discharge in Patients with Acute Heart Failure and Atrial Fibrillation. Journal of Korean Medical Science 2020, 35, e278 .
AMA StyleMin-Soo Ahn, Byung-Su Yoo, Jung-Woo Son, Min Heui Yu, Dae Ryong Kang, Hae-Young Lee, Eun-Seok Jeon, Jae-Joong Kim, Shung Chull Chae, Sang Hong Baek, Seok-Min Kang, Dong-Ju Choi, Kye Hun Kim, Myeong-Chan Cho, Seong Yoon Kim. Beta-blocker Therapy at Discharge in Patients with Acute Heart Failure and Atrial Fibrillation. Journal of Korean Medical Science. 2020; 35 (33):e278.
Chicago/Turabian StyleMin-Soo Ahn; Byung-Su Yoo; Jung-Woo Son; Min Heui Yu; Dae Ryong Kang; Hae-Young Lee; Eun-Seok Jeon; Jae-Joong Kim; Shung Chull Chae; Sang Hong Baek; Seok-Min Kang; Dong-Ju Choi; Kye Hun Kim; Myeong-Chan Cho; Seong Yoon Kim. 2020. "Beta-blocker Therapy at Discharge in Patients with Acute Heart Failure and Atrial Fibrillation." Journal of Korean Medical Science 35, no. 33: e278.