Prof. Lefkothea Papadopoulou

Lefkothea C. Papadopoulou is a Professor of Pharmacology in the School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, Macedonia, Greece. She completed her degree in Pharmacy from the School of Pharmacy, A.U.Th in 1980 and got her Ph.D. in Pharmacology at the same university in 1991, while she served as a Post-doctoral Research Fellow for two years (1996-1997) in Professor Eric Schon's Lab, under the supervision of the Department of Neurology of the College of Physicians and Surgeons, Columbia University in the City of New York. Her main interests include molecular mechanisms of action of antineoplastic agents, mitochondrial genetics and neurodegenerative disorders, Protein Transduction Domain (PTD) Technology, TAT-mediated protein transduction into mammalian cells as well as PTD-IVT-mRNA therapeutics as an alternative therapeutic approach for metabolic/monogenetic disorders, Immunotherapy - Cancer CAR-T/NK cell therapy as well Cellular Bioenergetics. Her research group recently designed a new delivery platform for any potentially therapeutic IVT-mRNA in combination with the Protein Transduction Domain (PTD) Technology, via a novel, patented conjugation reaction (Greek patent: ΔΕ1010063; International PCT/GR2020/000059, International publication number: WO 2021/094792 A1 / 20.05.2021), entitled “Method for the development of a delivery platform to produce deliverable PTD-IVT-mRNA therapeutics.”