Cycles of wetting and drying can change the microstructure of vegetable fibers through a mechanism known as hornification, which modifies the polymeric structure of the fiber-cells resulting in a higher dimensional stability. In the present work the influence of hornification on the sisal fiber-matrix bond adhesion as well as in the sisal fiber dimensional stability and mechanical behaviour under direct tension was evaluated. Furthermore, cementitious composites reinforced with randomly dispersed hornified sisal fibers were developed and characterized under bending loads. The results show that the tensile strength and strain at failure of the hornified sisal fibers were increased by about 5% and 39%, respectively, whereas the modulus of elasticity was reduced by 9%. The fibers also presented higher dimensional stability with the hornification process. The fiber-matrix bonding was improved and the pull-out resistance of the fibers submitted to ten cycles of wetting and drying was increased by about 40% to 50%. The higher fiber-matrix bond strength contributed to an increase in the ductility and post-cracking behaviour of the composite. The fracture process was characterized by the formation of multiple cracks with the hornified sisal fibers presenting a higher ability to bridge and arrest the cracks.