Martin Grözinger

Dr. Martin Grözinger


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 February 2025 in Diagnostics
Verified
Journal Article
Open access
PDF file
PLPatricia Leutz-Schmidt
Patricia Leutz-Schmidt
VPViktoria Palm
Viktoria Palm
RMRené Michael Mathy
René Michael Mathy
MGMartin Grözinger
Martin Grözinger
HKHans-Ulrich Kauczor
Hans-Ulrich Kauczor
SSSam Sedaghat
Sam Sedaghat
Background/Objectives: Despite the growing popularity of large language models (LLMs), there remains a notable lack of research examining their role in workplace management. This study aimed to address this gap by evaluating the performance of ChatGPT-3.5, ChatGPT-4.0, Gemini, and Gemini Advanced as famous LLMs in responding to workplace management questions specific to radiology. Methods: ChatGPT-3.5 and ChatGPT-4.0 (both OpenAI, San Francisco, CA, USA) and Gemini and Gemini Advanced (both Google Deep Mind, Mountain View, CA, USA) generated answers to 31 pre-selected questions on four different areas of workplace management in radiology: (1) patient management, (2) imaging and radiation management, (3) learning and personal development, and (4) administrative and department management. Two readers independently evaluated the answers provided by the LLM chatbots. Three 4-point scores were used to assess the quality of the responses: (1) overall quality score (OQS), (2) understandabilityscore (US), and (3) implementability score (IS). The mean quality score (MQS) was calculated from these three scores. Results: The overall inter-rater reliability (IRR) was good for Gemini Advanced (IRR 79%), Gemini (IRR 78%), and ChatGPT-3.5 (IRR 65%), and moderate for ChatGPT-4.0 (IRR 54%). The overall MQS averaged 3.36 (SD: 0.64) for ChatGPT-3.5, 3.75 (SD: 0.43) for ChatGPT-4.0, 3.29 (SD: 0.64) for Gemini, and 3.51 (SD: 0.53) for Gemini Advanced. The highest OQS, US, IS, and MQS were achieved by ChatGPT-4.0 in all categories, followed by Gemini Advanced. ChatGPT-4.0 was the most consistently superior performer and outperformed all other chatbots (p < 0.001–0.002). Gemini Advanced performed significantly better than Gemini (p = 0.003) and showed a non-significant trend toward outperforming ChatGPT-3.5 (p = 0.056). ChatGPT-4.0 provided superior answers in most cases compared with the other LLM chatbots. None of the answers provided by the chatbots were rated “insufficient”. Conclusions: All four LLM chatbots performed well on workplace management questions in radiology. ChatGPT-4.0 outperformed ChatGPT-3.5, Gemini, and Gemini Advanced. Our study revealed that LLMs have the potential to improve workplace management in radiology by assisting with various tasks, making these processes more efficient without requiring specialized management skills.

24 August 2023 in Diagnostics
Verified
Journal Article
Open access
PDF file
MSMarie Schierenbeck
Marie Schierenbeck
MGMartin Grözinger
Martin Grözinger
BRBenjamin Benjamin Reichardt
Benjamin Benjamin Reichardt
OJOlav Jansen
Olav Jansen
HKHans-Ulrich Kauczor
Hans-Ulrich Kauczor
SSSam Sedaghat
Sam Sedaghat
Background: Detecting bone marrow edema (BME) as a sign of acute fractures is challenging on conventional computed tomography (CT). This study evaluated the diagnostic performance of a three-material decomposition (TMD) approach for detecting traumatic BME of the extremities on spectral computed tomography (SCT). Methods: This retrospective diagnostic study included 81 bone compartments with and 80 without BME. A TMD application to visualize BME was developed in collaboration with Philips Healthcare. The following bone compartments were included: distal radius, proximal femur, proximal tibia, distal tibia and fibula, and long bone diaphysis. Two blinded radiologists reviewed each case independently in random order for the presence or absence of BME. Results: The interrater reliability was 0.84 (p < 0.001). The different bone compartments showed sensitivities of 86.7% to 93.8%, specificities of 84.2% to 94.1%, positive predictive values of 82.4% to 94.7%, negative predictive values of 87.5% to 93.3%, and area under the curve (AUC) values of 85.7% to 93.1%. The distal radius showed the highest sensitivity and the proximal femur showed the lowest sensitivity, while the proximal femur presented the highest specificity and the distal tibia presented the lowest specificity. Conclusions: Our TMD approach provides high diagnostic performance for detecting BME of the extremities. Therefore, this approach could be used routinely in the emergency setting.

12 April 2023 in British Journal of Radiology
Verified
Journal Article
Open access
Markus WennmannMarkus Wennmann
Markus Wennmann
MGMartin Grözinger
Martin Grözinger
VWVivienn Weru
Vivienn Weru
THThomas Hielscher
Thomas Hielscher
LRLukas Thomas Rotkopf
Lukas Thomas Rotkopf
Stefan DelormeStefan Delorme
Stefan Delorme
Objective: To investigate the reproducibility of size measurements of focal bone marrow lesions (FL) in MRI in patients with monoclonal plasma cell disorders under variation of patient positioning and observer. Methods: A data set from a prospective test–retest study was used, in which 37 patients with a total of 140 FL had undergone 2 MRI scans with identical parameters after patient repositioning. Two readers measured long and short axis diameter on the initial scan in T 1 weighted, T 2 weighted short tau inversion recovery and diffusion-weighted imaging sequences. The first reader additionally measured FL on the retest-scan. The Bland–Altman method was used to assess limits of agreement (LoA), and the frequencies of absolute size changes were calculated. Results: In the simple test–retest experiment with one identical reader, a deviation of ≥1 mm / ≥2 mm / ≥3 mm for the long axis diameter in T 1 weighted images was observed in 66% / 25% / 8% of cases. When comparing measurements of one reader on the first scan to the measurement of the other reader on the retest scan, a change of ≥1 mm / ≥3 mm / ≥5 mm for the long axis diameter in T 1 weighted images was observed in 78% / 21% / 5% of cases. Conclusion: Small deviations in FL size are common and probably due to variation in patient positioning or inter-rater variability alone, without any actual biological change of the FL. Knowledge of the uncertainty associated with size measurements of FLs is critical for radiologists and oncologists when interpreting changes in FL size in clinical practice and in clinical trials. Advances in knowledge: According to the MY-RADs criteria, size measurements of focal lesions in MRI are now of relevance for response assessment in patients with monoclonal plasma cell disorders. Size changes of 1 or 2 mm are frequently observed due to uncertainty of the measurement only, while the actual focal lesion has not undergone any biological change. Size changes of at least 6 mm or more in T 1 weighted or T 2 weighted short tau inversion recovery sequences occur in only 5% or less of cases when the focal lesion has not undergone any biological change.