Hisham S Khalil

Dr. Hisham S Khalil


Research Focus & Metrics

Academic Career Length

30Years (1997-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 July 2006 in Cochrane Database of Systematic Reviews
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Hisham S KhalilHisham S Khalil
Hisham S Khalil
DNDesmond A. Nunez
Desmond A. Nunez

23 June 2014 in The Journal of Laryngology & Otology
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Journal Article
Closed access
YMY B Mahalingappa
Y B Mahalingappa
Hisham S KhalilHisham S Khalil
Hisham S Khalil
Objective: We wanted to identify the presentation, diagnostic work-up and treatment outcomes of patients with sinonasal malignancy at Derriford Hospital, Plymouth, UK and compare these with the European Position Paper on Endoscopic Management of Tumours of the Nose, Paranasal Sinuses and Skull Base.Materials and methods: This was a retrospective audit of all patients diagnosed with sinonasal malignancy over a five-year period. The clinical records and picture archiving and communications system data of the patients were reviewed.Results: Thirty patients with sinonasal malignancy were identified out of 570 head and neck cancer patients. The nasal cavity was the most common site for presentation, followed by the maxillary sinuses. Fifty per cent of patients had a squamous cell carcinoma and 27 per cent had a malignant melanoma. Half of the patients presented at stage IV of the cancer and 20 per cent at stage III. Thirty-seven per cent of patients underwent surgical management and only 20 per cent of the total patient group underwent endoscopic surgery. The mortality in our series was 30 per cent over the studied period.Conclusion: Late-stage presentation of sinonasal malignancy has resulted in increased patient mortality in our case series. Also, we found a high incidence of malignant melanoma with high recurrence and survival rates.

1 April 1997 in Clinical Otolaryngology
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Journal Article
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IAI. Auf
I. Auf
JOJ.E. Osborne
J.E. Osborne
CSC. Sparkes
C. Sparkes
Hisham S KhalilHisham S Khalil
Hisham S Khalil

23 March 2011 in European Archives of Oto-Rhino-Laryngology
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Journal Article
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NCN. Clifton
N. Clifton
CKC. Klingmann
C. Klingmann
Hisham S KhalilHisham S Khalil
Hisham S Khalil

7 May 2011 in BMC Ear, Nose and Throat Disorders
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Hisham S KhalilHisham S Khalil
Hisham S Khalil
AEAhmed Z Eweiss
Ahmed Z Eweiss
NCNicholas Clifton
Nicholas Clifton
Functional endoscopic sinus surgery (FESS) is now a well-established strategy for the treatment of chronic rhinosinusitis which has not responded to medical treatment. There is a wide variation in the practice of FESS by various surgeons within the UK and in other countries.

4 September 2003 in BMC Ear, Nose and Throat Disorders
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Journal Article
Open access
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Hisham S KhalilHisham S Khalil
Hisham S Khalil
PWPaul C Windle-Taylor
Paul C Windle-Taylor
Canal wall down and canal wall up mastoidectomy represent two surgical approaches to middle ear cleft pathology. Very few studies have examined the effects of these procedures both on the patients' well being and on the resources needed to maintain that state. In this study the authors report the outpatient attendance pattern of canal wall down mastoidectomy patients This is a retrospective case-note review of 101 patients who underwent a CWD mastoidectomy at Derriford Hospital, Plymouth, UK. All surgery was performed by the senior author (PCW-T) between 1985 and 1997. The main outcome measures were the frequency of outpatients' visits, clinical problems at visit and the percentage of discharged patients. The studied patients made a total of 1341 outpatient visits between November 1985 and December 1998 with an average of 13.3 visits per patient (median of 11 visits). Almost two thirds of the group still attend for regular follow up. The greatest number of visits occurred in the first 24 months after surgery. The commonest reasons for outpatient visits were the removal of the clinical features of chronic cavity inflammation. Residual/recurrent cholesteatoma, residual perforations and structural cavity problems were infrequent. CWD mastoidectomy carries an intrinsic morbidity resulting in a long term attendance in the outpatients.