We retrieve ionization rates in the atmosphere caused by energetic electron precipitation from balloon observations in the polar atmosphere and compare them against ionization rates recommended for the Phase 6 of the Coupled Model Intercomparison Project. In our retrieval procedure, we consider the precipitating electrons with energies from about tens of keV to 5 MeV. Our simulations with 1‐D radiative‐convective model with interactive neutral and ion chemistry show that the difference of the Phase 6 of the Coupled Model Intercomparison Project and balloon‐based ionization rate can lead to underestimation of the NO_x enhancement by more than 100% and ozone loss up to 25% in the mesosphere. The atmospheric response is different below 50 km due to considering highly energetic electrons, but it is not important because the absolute values of atmospheric impact is tiny. Ionization rates obtained from the balloon observations reveal a high variability.

Phenothiazine and its derivatives have a number of properties that contribute to their wider practical use in the production of biologically active substances, drugs, dyes, etc. Therefore, the synthesis and study of new compounds is of great relevance. The aim of this work was to investigate the antioxidant activity of a number of new phenothiazine derivatives. The patterns of electroreduction of oxygen and its radicals in the presence of phenothiazine derivatives in aqueous ethanol media were studied by voltammetry. The influence of various factors on antioxidant activity was considered by the methods of experiment planning. The optimal conditions for the manifestation of the antioxidant activity of phenothiazine derivatives have been found, which seems to be relevant since it opens up new possibilities for their further use as complex preparations with antioxidant activity, including in psychiatric practice.

Introduction : A blood test can provide important information about the functional state of the antioxidant system. Malfunction of this system increases the concentration of free radicals and can cause oxidative stress. A difficulty in assessing oxidative stress is the lack of a universal method...

A new model of the family of CRAC models, CRAC:EPII (Cosmic Ray Atmospheric Cascade: Electron Precipitation Induced Ionization), is presented. The model calculates atmospheric ionization induced by precipitating electrons and uses the formalism of ionization yield functions. The CRAC:EPII model is based on a full Monte Carlo simulation of electron propagation and interaction with the air molecules. It explicitly considers various physical processes, namely, pair production, Compton scattering, generation of bremsstrahlung high‐energy photons, photoionization, annihilation of positrons, and multiple scattering. The simulations were performed using GEANT 4 simulation tool PLANETOCOSMICS with NRLMSISE 00 atmospheric model. The CRAC:EPII model is applicable to the entire atmosphere. The results from the simulations are given as look‐up table representing the ionization yield function. The table allows one to compute ionization due to precipitating electrons for a given altitude and location considering a given electron spectrum. Application of the model for computation of ion production during electron precipitation events using spectra from balloon‐borne measurements is presented.