LIRON SINVANI

Dr. LIRON SINVANI

orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 June 2021 in Western Journal of Emergency Medicine
Verified
Journal Article
Open access
PDF file
KLKate van Loveren
Kate van Loveren
ASArnav Singla
Arnav Singla
LSLIRON SINVANI
LIRON SINVANI
CCChristopher Calandrella
Christopher Calandrella
TPThomas Perera
Thomas Perera
TLTimmy Li
Timmy Li
Introduction: Our study aimed to determine 1) the association between time spent in the emergency department (ED) hallway and the development of delirium and 2) the hospital location of delirium development.Methods: This single-center, retrospective chart review included patients 18+ years old admitted to the hospital after presenting, without baseline cognitive impairment, to the ED in 2018. We identified the Delirium group by the following: key words describing delirium; orders for psychotropics, special observation, and restraints; or documented positive Confusion Assessment Method (CAM) screen. The Control group included patients not meeting delirium criteria. We used a multivariable logistic regression model, while adjusting for confounders, to assess the odds of delirium development associated with percentage of ED LOS spent in the hallway.Results: A total of 25,156 patients met inclusion criteria with 1920 (7.6%) meeting delirium criteria. Delirium group vs. Control group patients spent a greater percentage of time in the ED hallway (median 50.5% vs 10.8%, P<0.001); had longer ED LOS (median 11.94 vs 8.12 hours, P<0.001); had more ED room transfers (median 5 vs 4, P<0.001); and had longer hospital LOS (median 5.0 vs 4.6 days, P<0.001). Patients more frequently developed delirium in the ED (77.5%) than on inpatient units (22.5%). The relative odds of a patient developing delirium increased by 3.31 times for each percent increase in ED hallway time (95% confidence interval, 2.85, 3.83).Conclusion: Patients with delirium had more ED hallway exposure, longer ED LOS, and more ED room transfers. Understanding delirium in the ED has substantial implications for improving patient safety.

1 July 2024 in JAMA Internal Medicine
Verified
Journal Article
Closed access
PDF file
AMAlexander Makhnevich
Alexander Makhnevich
APAlexandra Perrin
Alexandra Perrin
DTDristi Talukder
Dristi Talukder
YLYan Liu
Yan Liu
SIStephanie Izard
Stephanie Izard
LSLIRON SINVANI
LIRON SINVANI
Importance: Oropharyngeal dysphagia is common in hospitalized patients with Alzheimer disease and related dementias (ADRD). Although the use of thick liquids in patients with dysphagia has been shown to reduce aspiration on direct visualization, there is no clear evidence that this practice translates into improved clinical outcomes.Objectives: To determine whether a diet of thick liquids compared with thin liquids is associated with improved outcomes in hospitalized patients with ADRD and dysphagia.Design, Setting, and Participants: This cohort study included adults aged 65 years and older with ADRD who were admitted to the medicine service across 11 diverse hospitals in New York between January 1, 2017, and September 20, 2022, with clinical suspicion of dysphagia during hospitalization and survival for at least 24 hours after hospital arrival. Patients were grouped according to whether at least 75% of their hospital diet consisted of a thick liquid diet or a thin liquid diet. Propensity score matching was used to balance covariates across the 2 groups for the following covariates: demographics (eg, age, sex), baseline clinical characteristics (eg, Charlson Comorbidity Index), and acute presentation (eg, respiratory diagnosis, illness severity, delirium).Main Outcomes and Measures: Hospital outcomes included mortality (primary outcome), respiratory complications (eg, pneumonia), intubation, and hospital length of stay (LOS).Results: Of 8916 patients with ADRD and dysphagia included in the propensity score matched analysis, the mean (SD) age was 85.7 (8.0) years and 4829 were female (54.2%). A total of 4458 patients receiving a thick liquid diet were matched with 4458 patients receiving a thin liquid diet. There was no significant difference in hospital mortality between the thick liquids and thin liquids groups (hazard ratio, 0.92; 95% CI, 0.75-1.14]; P = .46). Compared with patients receiving thin liquids, patients receiving thick liquids were less likely to be intubated (odds ratio [OR], 0.66; 95% CI, 0.54-0.80), but they were more likely to have respiratory complications (OR, 1.73; 95% CI, 1.56-1.91).Conclusions and Relevance: This cohort study emphasizes the need for prospective studies that evaluate whether thick liquids are associated with improved clinical outcomes in hospitalized patients with ADRD and dysphagia.

11 August 2018 in Journal of the American Geriatrics Society
Verified
Journal Article
Closed access
PDF file
LSLIRON SINVANI
LIRON SINVANI
JWJessy Warner‐Cohen
Jessy Warner‐Cohen
ASAndrew Strunk
Andrew Strunk
THTravis Halbert
Travis Halbert
RHRuchika Harisingani
Ruchika Harisingani
CKCorey Karlin‐Zysman
Corey Karlin‐Zysman

1 August 2021 in Journal of Pain and Symptom Management
Verified
Journal Article
Closed access
SLSantiago Lopez
Santiago Lopez
KFKayla D. Finuf
Kayla D. Finuf
AMAllison Marziliano
Allison Marziliano
LSLIRON SINVANI
LIRON SINVANI
EBEdith A. Burns
Edith A. Burns

16 August 2021 in Journal of the American Geriatrics Society
Verified
Journal Article
Closed access
PDF file
LSLIRON SINVANI
LIRON SINVANI
CSCynthia Delle Site
Cynthia Delle Site
TLTara Laumenede
Tara Laumenede
VPVidhi Patel
Vidhi Patel
SASuzanne Ardito
Suzanne Ardito
LTLily Thomas
Lily Thomas

11 May 2020 in Journal of the American Geriatrics Society
Verified
Journal Article
Closed access
PDF file
LSLIRON SINVANI
LIRON SINVANI
MGMark Goldin
Mark Goldin
RRRegina Roofeh
Regina Roofeh
NINayla Idriss
Nayla Idriss
AGAriel Goldman
Ariel Goldman
MCMaria Torroella Carney
Maria Torroella Carney