Objective: This study aimed to evaluate the efficacy of MRI-based Apparent Diffusion Coefficient (ADC) measurements in detecting axillary lymph node metastasis in breast cancer patients. By comparing preoperative MRI findings with intraoperative sentinel lymph node biopsy (SLNB) and postoperative pathological results, we sought to explore the potential of ADC values as a non-invasive alternative to axillary interventions. Methods: A total of 104 female patients diagnosed with breast cancer between 2019 and 2021 were included in this prospective study. ADC values of axillary lymph nodes, tumors, and muscle tissues were measured using a 3T MRI system. The correlation between these measurements and pathological outcomes was analyzed. Statistical analyses, including t-tests, ANOVA, and ROC curve analysis, were employed to assess the diagnostic performance of ADC values. Results: The results indicated that, while the mean ADC values of metastatic lymph nodes were lower than those of benign nodes, the sensitivity and specificity of MRI-based ADC measurements were inferior to the expected standards. The tumor ADC value and the tumor-to-lymph node ADC ratio were found to be more reliable indicators of metastasis than the lymph node ADC value alone. The diagnostic power of the tumor ADC value was significant, with a sensitivity of 75% and a specificity of 73%. Conclusions: MRI-based ADC measurements, particularly the tumor ADC value and the tumor-to-lymph node ADC ratio, show promise as potential non-invasive markers for axillary lymph node metastasis in breast cancer patients. However, the current results suggest that ADC measurements cannot yet replace SLNB in clinical practice.
Background and Objectives: The selection of an appropriate anesthesia method is a critical factor in the surgical treatment of proctological diseases, significantly impacting patient outcomes and comfort. Pudendal nerve block (PNB) and spinal anesthesia (SA) are commonly employed in these surgeries, yet the optimal choice between the two remains debated. This study aims to compare the efficacy and safety of PNB and SA in patients undergoing surgical treatment for various proctological conditions, with a focus on postoperative pain management, functional outcomes, and complication rates. Materials and Methods: A prospective observational study was conducted on 590 patients who underwent proctological surgery under either PNB (n = 435) or SA (n = 155). Pain levels were assessed using the Visual Analog Scale (VAS), while functional outcomes were measured using the World Health Organization Disability Assessment Schedule (WHODAS 2.0). Statistical analysis was performed to compare the outcomes between the two groups. Results: Patients in the PNB group reported significantly lower postoperative VAS scores compared to those in the SA group, particularly in hemorrhoidectomy and laser hemorrhoidoplasty procedures. The PNB group also demonstrated superior functional outcomes, with lower postoperative WHODAS 2.0 scores and a reduced incidence of urinary retention compared to the SA group. Furthermore, the duration of surgery and hospital stay were significantly shorter for patients in the PNB group. Conclusions: The findings suggest that PNB may offer advantages over SA in proctological surgeries, particularly in terms of pain management, functional recovery, and reduced complication rates. PNB should be considered a viable alternative to SA, particularly in cases where rapid recovery and minimizing complications are priorities. Exceptions to this include specific proctological surgeries, such as those for malignant tumors in the region, complex anal fistulas, proctological conditions arising from inflammatory bowel diseases, and patients on immunosuppressive therapy. Further research is needed to confirm these results and optimize anesthesia selection in this context.
12 August 2025 in International Journal of Surgical Pathology
Idiopathic granulomatous mastitis (IGM) is a chronic inflammatory breast disease. Patients typically present with a painful or painless mass and signs of inflammation. While IGM is already rare in women, only a few male patients have been reported in the literature. In this article we present the case report of a 63-year-old male patient with IGM, which clinically and radiologically mimicked male breast cancer. Radiological findings in the patient were nonspecific. Definitive diagnosis was made by histopathological evaluation. Surgical excision was performed as a treatment modality. No recurrence or residual lesion was detected in postoperative follow-up.
Background and Objectives: Ventral hernias (VH) pose significant challenges for surgeons due to the risk of recurrence, complexities in aligning abdominal muscles, and selecting the most suitable layer for mesh augmentation. This study aims to evaluate the effectiveness of utilizing the anterior rectus fascia as a turnover flap in conjunction with onlay mesh reinforcement, a procedure known as the modified Chevrel technique (MCT). Materials and Methods: We conducted a retrospective analysis of patients who were operated on using MCT for abdominal hernias between January 2013 and December 2019. Data were extracted from our hospital’s electronic database. Recurrence rates, as well as the rates of surgical site occurrences (SSO), surgical site infections (SSI), and surgical site occurrences requiring procedural intervention (SSOPI), were analyzed based on patients’ comorbidities and demographic characteristics. Results: The median follow-up period was 42.9 months (range: 14–96), and the recurrence rate was 4% (n = 3). Among the recurrent cases, three patients had chronic obstructive pulmonary disease, representing a statistically significant association (p = 0.02). Although all patients with recurrence were obese, this association did not reach statistical significance (p > 0.05). The mean hospitalization duration was 17.6 days (range: 6–29). SSO, SSI, and SSOPI rates were 39 (52%), 12 (16%), and 32 (42%), respectively. Conclusions: Managing VH remains a surgical challenge, emphasizing the importance of achieving effective abdominal closure for both functional and cosmetic outcomes. MCT presents a relatively simple approach compared to techniques like transversus abdominis release (TAR) and anterior component separation (ACS), with acceptable rates of SSO, SSOPI, SSI, and recurrence.
30 April 2024 in Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi
The aim of this study is to retrospectively analyze the cases who underwent upper and lower gastrointestinal system endoscopic evaluation between 2021-2022 in the endoscopy unit, which was established for the first time in a second level hospital, and to emphasize the importance of endoscopy units in district hospitals located far from central hospitals. The study comes to the fore in terms of dealing with the data of a district hospital where an endoscopy unit was established for the first time. The data of 440 patients who underwent endoscopic evaluation were analyzed. The study included 320 patients who underwent upper gastrointestinal tract and 120 who underwent lower gastrointestinal tract endoscopic examination. The endoscopic and pathological diagnoses given to patients were examined based on the data obtained, and descriptive statistics were performed. The cases undergoing upper gastrointestinal endoscopic examination had a mean age of 53.93±16.14 years, and those undergoing lower gastrointestinal tract endoscopic examination had a mean age of 53.71±15.86. Of cases undergoing upper gastrointestinal tract endoscopic examination, 70.3% had antral gastritis (n=225), 34.8% had ulcers (n=111), 10.3% had hiatus hernia (n=28), 9.1% had esophagitis (n=29), and 9.1% had duodenitis (n=29). Among the cases endoscopically diagnosed with cancer, 0.9% were localized in the distal esophagus (n=3) and 0.6% in the antrum (n=3). Of cases undergoing lower gastrointestinal tract endoscopic examination, 20% were diagnosed with polyp (n=24), 10% with diverticulum (n=12), 3.3% with hemorrhoidal disease (n=4), and 5% with cancer (n=6). As a result, the data obtained from the study emphasize the importance of endoscopy units in district hospitals located far from central hospitals.
Incisional hernia is the most common long-term complication following abdominal surgery, resulting in considerable morbidity and the need for reoperation.