The largest disaster reduction and relocation project was conducted in Shaanxi Province, China, in an effort to reduce the threat of natural disasters and preserve the environment. Although the literature has attempted to assess the economic and ecological impacts of the project quantitatively, there is currently a dearth of research on the connection between resource dependence and adaptive capacity at the rural household levels. Using survey data from southern Shaanxi, China, this study evaluated and quantified natural resource dependence (NRD) and household adaptive capacity (HAC) in the context of disaster resettlement. Simultaneously, we explored the differences in NRD and HAC among various groups and relocation characteristics. An ordinary least squares regression model was used to specifically examine the relationship between them. The results indicated that, first, NRD was significantly and positively related to HAC. Second, the dependence of relocated households on energy, food, and income had a significantly positive correlation with HAC. Third, compared to local, involuntary, and scattered resettlement households, the HAC of relocated households, voluntary relocated households, and centralized resettlement households is substantially lower. The aforementioned findings have significant policy implications for rural China and other developing nations, as they can help reduce natural resource dependence and increase adaptive capacity.