OLYMPIA PAPAKONSTANTINOU

Prof. OLYMPIA PAPAKONSTANTINOU

orcid

Research Focus & Metrics

Academic Career Length

33Years (1994-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 January 2015 in Insights into Imaging
Verified
Journal Article
Open access
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Dimitrios FilippiadisDimitrios Filippiadis
Dimitrios Filippiadis
AMArgyro Mazioti
Argyro Mazioti
SAS. Argentos
S. Argentos
GAG. Anselmetti
G. Anselmetti
OLYMPIA PAPAKONSTANTINOUOLYMPIA PAPAKONSTANTINOU
OLYMPIA PAPAKONSTANTINOU
Alexis  KelekisAlexis Kelekis
Alexis Kelekis
Excessive lordosis is a common finding and may produce mechanical pressure that causes repetitive strains of the interspinous ligament with subsequent degeneration and collapse. Baastrup’s disease (kissing spine syndrome) is a term referring to close approximation of adjacent spinous processes due to degenerative changes of the spine. Baastrup’s disease usually affects the lumbar spine, with L4-L5 being the most commonly affected level. There is higher occurrence at ages over 70 and no gender predilection. Symptoms include back pain with midline distribution that worsens during extension, is relieved during flexion and is exaggerated upon finger pressure at the level of interest. Diagnosis rests on clinical examination and imaging studies. The hallmark of imaging findings is the close approximation and contact of adjacent spinous processes, with all the subsequent findings including oedema, cystic lesions, sclerosis, flattening and enlargement of the articulating surfaces, bursitis and occasionally epidural cysts or midline epidural fibrotic masses. Proposed therapies include conservative treatment, percutaneous infiltrations or surgical therapies such as excision of the bursa or osteotomy. The purpose of this study is to illustrate the spectrum of imaging findings in Baastrup’s disease and to emphasise upon including the syndrome in the list of potential causes of low-back pain. Teaching Points • Baastrup’s disease refers to close approximation of adjacent spinous processes. • Diagnosis of Baastrup’s disease is verified with clinical examination and imaging studies. • Contact of adjacent spinous processes results in oedema, sclerosis, flattening and enlargement. • Proposed therapies include conservative treatment, percutaneous infiltrations or surgical therapies.

4 July 2025 in Diagnostics
Verified
Journal Article
Open access
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PPPlaton S. Papageorgiou
Platon S. Papageorgiou
Rafail C. ChristodoulouRafail C. Christodoulou
Rafail C. Christodoulou
PKPanagiotis Korfiatis
Panagiotis Korfiatis
DPDimitra Papagelopoulos
Dimitra Papagelopoulos
OLYMPIA PAPAKONSTANTINOUOLYMPIA PAPAKONSTANTINOU
OLYMPIA PAPAKONSTANTINOU
PPPanayiotis J. Papagelopoulos
Panayiotis J. Papagelopoulos
Artificial Intelligence (AI) has emerged as a transformative force in orthopedic oncology, offering significant advances in the diagnosis, classification, and prediction of treatment response for primary malignant bone tumors (PBT). Through machine learning and deep learning techniques, AI leverages computational algorithms and large datasets to enhance medical imaging interpretation and support clinical decision-making. The integration of radiomics with AI enables the extraction of quantitative features from medical images, allowing for precise tumor characterization and the development of personalized therapeutic strategies. Notably, convolutional neural networks have demonstrated exceptional capabilities in pattern recognition, significantly improving tumor detection, segmentation, and differentiation. This narrative review synthesizes the evolving applications of AI in PBTs, focusing on early tumor detection, imaging analysis, therapy response prediction, and histological classification. AI-driven radiomics and predictive models have yielded promising results in assessing chemotherapy efficacy, optimizing preoperative imaging, and predicting treatment outcomes, thereby advancing the field of precision medicine. Innovative segmentation techniques and multimodal imaging models have further enhanced healthcare efficiency by reducing physician workload and improving diagnostic accuracy. Despite these advancements, challenges remain. The rarity of PBTs limits the availability of robust, high-quality datasets for model development and validation, while the lack of standardized imaging protocols complicates reproducibility. Ethical considerations, including data privacy and the interpretability of complex AI algorithms, also warrant careful attention. Future research should prioritize multicenter collaborations, external validation of AI models, and the integration of explainable AI systems into clinical practice. Addressing these challenges will unlock AI’s full potential to revolutionize PBT management, ultimately improving patient outcomes and advancing personalized care.

1 September 2012 in Magnetic Resonance Imaging
Verified
Journal Article
Closed access
OLYMPIA PAPAKONSTANTINOUOLYMPIA PAPAKONSTANTINOU
OLYMPIA PAPAKONSTANTINOU
KFKostantina Foufa
Kostantina Foufa
OBOdysseas Benekos
Odysseas Benekos
EAEfthymia Alexopoulou
Efthymia Alexopoulou
MMMaria Mademli
Maria Mademli
NKNikolaos L. Kelekis
Nikolaos L. Kelekis

30 January 2019 in Seminars in Musculoskeletal Radiology
Verified
Journal Article
Closed access
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AIAmanda Isaac
Amanda Isaac
DDDanoob Dalili
Danoob Dalili
INIris-Melanie Noebauer-Huhmann
Iris-Melanie Noebauer-Huhmann
OLYMPIA PAPAKONSTANTINOUOLYMPIA PAPAKONSTANTINOU
OLYMPIA PAPAKONSTANTINOU
Most musculoskeletal tumors are hyperintense on T2-weighted images. However, some T2-weighted hypointense tumors and tumor-like lesions are encountered in everyday clinical practice. We explore the spectrum of such T2 hypointense tumors and tumor mimickers that can arise from (1) the bones, presenting as diffuse processes or focal lesions; (2) the joints including diffuse or focal synovial disorders, loose bodies, or substance depositions; and (3) soft tissues, comprising T2 hypointense tumors and tumor mimickers (those that contain abundant fibrous tissue, mineralization, or hemosiderin deposits). Appropriate magnetic resonance imaging sequence selection is required to identify and characterize these lesions confidently when imaging musculoskeletal tumors.

30 September 2021 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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TOTarimobo Michael Otobo
Tarimobo Michael Otobo
NHNele Herregods
Nele Herregods
JJJacob Lester Jaremko
Jacob Lester Jaremko
Iwona Sudoł-SzopińskaIwona Sudoł-Szopińska
Iwona Sudoł-Szopińska
WMWalter Maksymowych
Walter Maksymowych
ADAndrea S. Doria
Andrea S. Doria
This study reports the reliability of the juvenile idiopathic arthritis magnetic resonance imaging scoring system (JAMRIS-SIJ). The study comprised of eight raters—two rheumatologists and six radiologists—and 30 coronal T1 and Short-Tau Inversion Recovery (STIR) MRI scans of patients with enthesitis-related juvenile spondylarthritis. The median age of patients was 15 years with a mean disease duration of 5 years and 22 (73.3%) of the sample were boys. The inter-rater agreement of scores for each of the JAMRIS-SIJ items was calculated using a two-way random effect, absolute agreement, and single rater intraclass correlation coefficient (ICC 2.1). The ICC was interpreted together with kurtosis, since the ICC is also affected by the distribution of scores in the sample. The eight-rater, single measure inter-rater ICC (and kurtosis) values for JAMRIS-SIJ inflammation and damage components were the following: bone marrow edema (BME), 0.76 (1.2); joint space inflammation, 0.60 (1.8); capsulitis, 0.58 (9.2); enthesitis, 0.20 (0.1); ankylosis, 0.89 (35); sclerosis, 0.53 (4.6); erosion, 0.50 (6.5); fat lesion, 0.40 (21); backfill, 0.38 (38). The inter-rater reliability for BME and ankylosis scores was good and met the a priori set ICC threshold, whereas for the other items it was variable and below the selected threshold. Future directives should focus on refinement of the scores, definitions, and methods of interpretation prior to validation of the JAMRIS-SIJ through the assessment of its measurement properties.

1 January 1994 in Abdominal Radiology
Verified
Journal Article
Closed access
PDF file
NGN. C. Gourtsoyiannis
N. C. Gourtsoyiannis
OLYMPIA PAPAKONSTANTINOUOLYMPIA PAPAKONSTANTINOU
OLYMPIA PAPAKONSTANTINOU
DBD. Bays
D. Bays
MMM. Malamas
M. Malamas